Determining Stereochemical Relationships:
Comparing Acyclic Structures Using the R and S Method
You have selected to use the R and S Method for determining the stereochemical relationships between molecules drawn in different acyclic three-dimensional representations. Using this method requires four steps:
Step 1: Determine that the molecules have the same molecular formula and connectivity.
For example, compare the molecules below.
Do these molecules have the same molecular formula and connectivity?
The above two molecules do have the same molecular formula (C5
O) and the same connectivity.
Find the stereocenter(s) on each molecule.
Again consider the above pair of molecules and find the stereocenter(s) on each.
to check your answer and continue on.
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