26.2 Amino Acids, the Henderson-Hasselbalch Equation, and Isoelectric Points
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Denaturation of Protein by Strong AcidJohn W. Moore, Jerrold J. Jacobsen, Gary Trammell, Kristin Johnson "Strong acid denatures egg white proteins.This video contains voiceover:""The tertiary structure of egg white proteins is held together by hydrogen bonding and hydrophobic interactions. Adding strong acid to the protein disrupts the intermolecular forces, and the tertiary structure is lost. The loss in protein structure is called denaturation. The proteins precipitate, forming a white solid."""
The Monosodium Glutamate Story: The Commercial Production of MSG and Other Amino AcidsAddison Ault Examples of the industrial synthesis of pure amino acids are presented. The emphasis is on the synthesis of (S)-glutamic acid and, to a lesser extent, (S)-lysine and (R,S)-methionine. These amino acids account for about 90% of the total world production of amino acids. Ault, Addison. J. Chem. Educ.2004, 81, 347.
Amino Acids |
Biotechnology |
Chirality / Optical Activity |
Consumer Chemistry |
Enzymes |
Natural Products |
Stereochemistry |
Synthesis |
Food Science
The pH at the First Equivalence Point in the Titration of a Diprotic AcidAddison Ault I read with interest the paper entitled Easy Derivation of pH (pKa1 + pKa2)/2 Using Autoprotolysis of HA: Doubtful Value of the Supposedly More Rigorous Equation. I believe the validity of this simple result can be seen even more easily than this paper indicates. Ault, Addison. J. Chem. Educ.2003, 80, 1382.
Acids / Bases |
Equilibrium |
pH |
Titration / Volumetric Analysis
Do pH in Your HeadAddison Ault Every aqueous solution has a pH. Two factors determine this pH: the acidic or basic strength of the solute, and its concentration. When you use pKa values to express acidic and basic strength you can easily estimate the approximate pH of many aqueous solutions of acids, bases, and their salts and their buffers. Ault, Addison. J. Chem. Educ.1999, 76, 936.
Amphiprotic SpeciesEd Vitz, John W. Moore A section of ChemPrime, the Chemical Educations Digital Library's free General Chemistry textbook.
Acids / Bases |
Amino Acids
ChemPaths 104 W Feb 2John W. Moore Today in Chem 104:
* Lecture: Biochemistry: Proteins
* Reading: Biomolecules Tutorials
o Proteins 1 (including debriefing)
o Proteins 2 (including debriefing)
o Quiz due TODAY, 11:55 PM)
* Homework #3 due by 11:55pm F Feb 4.
Proteins / Peptides |
Amino Acids
Organic Nitrogen CompoundsEd Vitz, John W. Moore A section of ChemPrime, the Chemical Educations Digital Library's free General Chemistry textbook.