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For the textbook, chapter, and section you specified we found
5 Videos
2 Assessment Questions
7 Journal Articles
4 Other Resources
Videos: First 3 results
Chiral and Achiral Objects  
A snail shell, pencil, glove, hand, and molecular models are shown with their mirror reflections.
Chirality / Optical Activity
Polarized Light and Organic Molecules: Everyday Objects  
The liquid crystal display of a calculator and several plastic objects are examined between polarizing filters.
Chirality / Optical Activity
Polarized Light and Organic Molecules  
Polarizing filters and the rotation of polarized light by chiral compounds are demonstrated and a polarimeter is shown. Several everyday objects are examined between polarizing filters.
Chirality / Optical Activity
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Assessment Questions: 2 results
Organic : IDChiralAtoms (20 Variations)
Identify the chiral carbon atom(s), if any, in the following structure. The carbon atoms have been numbered for easier identification.



Alkanes / Cycloalkanes |
Chirality / Optical Activity
Stereochemistry (21 Variations)
A collection of 21 assessment questions about Stereochemistry
Stereochemistry |
Conformational Analysis |
Chirality / Optical Activity |
Alkanes / Cycloalkanes |
Alkenes |
Alcohols |
Enantiomers |
Diastereomers |
Carbohydrates |
Carboxylic Acids |
Nomenclature / Units / Symbols |
Esters
Journal Articles: First 3 results.
Pedagogies:
Chemical Aspects of General Anesthesia: Part I. From Ether to Halothane  Robert Brunsvold and Daryl L. Ostercamp
Summarizes general anesthesia from 1846 to 1956. Events leading up to the adoption of a "balanced" approach, where a sequence of individual compounds is used rather than a single agent, are described.
Brunsvold, Robert; Ostercamp, Daryl L. J. Chem. Educ. 2006, 83, 1821.
Acids / Bases |
Bioorganic Chemistry |
Chirality / Optical Activity |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Synthesis
Enantiomeric Resolution of (±)-Mandelic Acid by (1R,2S)-(–)-Ephedrine. An Organic Chemistry Laboratory Experiment Illustrating Stereoisomerism  Marsha R. Baar and Andrea L. Cerrone-Szakal
There has been an increasing need, particularly in the pharmaceutical industry, to prepare chiral substances in single-isomer form. A chiral technique that makes an excellent introductory organic chemistry experiment is enantiomeric resolution. The classical resolution of ()-mandelic acid using the chiral amine, (1R,2S)-()-ephedrine, was adapted for use in introductory organic chemistry lab curricula.
Baar, Marsha R.; Cerrone-Szakal, Andrea L. J. Chem. Educ. 2005, 82, 1040.
Acids / Bases |
Chirality / Optical Activity |
Separation Science |
Stereochemistry |
Diastereomers |
Enantiomers
Introducing Stereochemistry to Non-science Majors  Hannia Luján-Upton
Two exercises to introduce concepts associated with stereochemistry such as "sameness", superimposability, chirality, enantiomers, optical activity, polarimetry, and racemic mixtures; one compares chirality in hands with the achiral nature of two textbooks, the other involves a murder mystery.
Luján-Upton, Hannia. J. Chem. Educ. 2001, 78, 475.
Chirality / Optical Activity |
Stereochemistry |
Nonmajor Courses |
Molecular Properties / Structure
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Other Resources: First 3 results
Properties of Alkanes  Ed Vitz, John W. Moore
A section of ChemPrime, the Chemical Educations Digital Library's free General Chemistry textbook.
Chirality / Optical Activity
Collection of Chiral Drug, Pesticide, and Fragrance Molecular Models  William F. Coleman
The article by Mannschreck, Kiessewetter, and von Angerer on the differential interactions between enantiomers and biological receptors (1) is the source for this month's Featured Molecules. Included in the molecule collection are all of the molecules described in the paper. In many instances we have included structures of multiple optical isomers of the same molecule so that students can not only see the forms that are active, but those that are less active, inactive, or act in an undesirable manner. These molecules will serve as good practice in determining optical configurations, and will also introduce additional forms of isomerism that students may be less familiar with than they are with R and S. Since multiple enantiomers and diastereomers are provided, students may use these molecules, together with an appropriate computational package, to verify that enantiomers have the same energy while diastereomers do not. The tuberculosis drug ethambutol provides an interesting case as both nitrogen atoms are also chiral as well as the two chiral carbon atoms. A calculation on a given structure will include the effect of that nitrogen chirality, although nitrogen inversion is expected to be quite rapid in this molecule. The conformations for the ethambutol molecules that are included here consider all four chiral atoms and are of the form (CNNC). A reasonable computational exercise would be to find the transition state for nitrogen inversion and the barrier height for that process. The supplemental material that is included with the featured article (1) includes a number of molecules that we will add to the collection as time permits. The result, including enantiomers and diastereomers, will be well over 200 additional molecules. A notice will appear in the JCE Featured Molecules column when this new set of molecules is available in JCE Online.
Chirality / Optical Activity |
Biosignaling
Stereochemistry Tutorial  Nicola Burrmann
Master the concepts organic stereochemistry with this interactive tutorial. It includes definitions, different three dimensional representations, assigning priorities to stereocenters, and determining the stereochemical relationship between molecules. Each section is followed by a question set that tests knowledge and understanding.
Stereochemistry |
Chirality / Optical Activity
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