Click on the title of a resource to view it. To save screen space, only the first 3 resources are shown. You can display more resources by scrolling down and clicking on “View all xx results”.
For the textbook, chapter, and section you specified we found
Denaturation of Protein by Strong AcidJohn W. Moore, Jerrold J. Jacobsen, Gary Trammell, Kristin Johnson "Strong acid denatures egg white proteins.This video contains voiceover:""The tertiary structure of egg white proteins is held together by hydrogen bonding and hydrophobic interactions. Adding strong acid to the protein disrupts the intermolecular forces, and the tertiary structure is lost. The loss in protein structure is called denaturation. The proteins precipitate, forming a white solid."""
Extraction of Acid with Base Water and diethyl ether are shaken in a separatory funnel with a small amount of red indophenol. The non-ionic indophenol remains in the ether layer, coloring it red. Addition of sodium hydroxide converts the indophenol to its blue ionic acid anion which is extracted into the water layer turning it blue.
Reactions : AcidBaseRxns (20 Variations) In order to answer the following questions, write the net ionic equation for the reaction between equal volumes of 0.10 M solutions of the following acid and base:
KOH(aq) + HBr(aq)
What are the reaction products? Does the reaction yield an acidic, basic, or neutral aqueous solution?
A Web-Based Interactive Module to Teach Acid–Base Principles of Drug ActionMaria A. Hernandez and Jolanta Czerwinska Describes interactive compressed video teleconferencing as the distance learning format for an entry-level doctor of pharmacy program. Hernandez, Maria A.; Czerwinska, Jolanta. J. Chem. Educ.2008, 85, 1704.
Acids / Bases |
Drugs / Pharmaceuticals
Real-World Topics: Medicinal ChemistryArrietta Clauss Instructors often look for real-world topics that interest students when designing labs and preparing lectures. The chemistry associated with drugs is a fertile area, and the archives of the Journal can be a resource for interesting drug-related activities to enhance student learning. Clauss, Arrietta. J. Chem. Educ.2008, 85, 1657.
Enrichment / Review Materials |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Applications of Chemistry
Investigating the Stability of Benzoyl Peroxide in Over-the-Counter Acne MedicationsMarina Canepa Kittredge, Kevin W. Kittredge, Melissa S. Sokol, Arlyne M. Sarquis, and Laura M. Sennet Students use peroxide strips to investigate the stability of the benzoyl peroxide found in an over-the-counter acne medication when added to various solutions of water, ethanol, polyethylene glycol, and isopropyl myristate. Canepa Kittredge, Marina; Kittredge, Kevin W.; Sokol, Melissa S.; Sarquis, Arlyne M.; Sennet, Laura M. J. Chem. Educ.2008, 85, 1655.
Molecular Models of Real and Mock Illicit Drugs from a Forensic Chemistry ActivityWilliam F. Coleman The Featured Molecules for this month come from the paper by Shawn Hasan, Deborah Bromfield-Lee, Maria T. Oliver-Hoyo, and Jose A. Cintron-Maldonado (1). The authors describe a forensic chemistry exercise in which model compounds are used to simulate the behavior of various drugs in a series of chemical tests. Structures of a number of the chemicals used in the experiment, and several of the drugs they are serving as proxy for, have been added to the molecule collection. Other substances used in the experiment are already part of the collection, including caffeine and aspirin. One structure that may be both intriguing and confusing to students is that of chlorpromazine (Thorazine, Figure 1). A majority of students might well expect the ring portion of the molecule to show a planar structure. This is not what is found from calculations at the HF/6311++G(d,p) level in both the gas phase and in water. Instead, the three rings are in a V-like formation with a deformation of approximately 50 degrees from planarity. Tracking down the source of this non-planarity would be a useful computational exercise. Does it arise from the presence of the alkyl chain (steric effect), from the chloro group (electronic effect), or from electronic effects involving the elements of the heterocyclic ring? As a starting point to addressing these questions, students could be introduced to the use of model compounds in computation. One such compound would be the parent ring system phenothiazine (Figure 2). That molecule contains neither a chloro substituent nor an extended alkyl group. Is it also found to be non-planar? Is the deformation angle the same, larger, or smaller than in chlorpromazine? Does the addition of chloro group to phenothiazene change the angle significantly? What about the addition of an alkyl group? If the model compound is forced to be planar are all of the vibrational frequencies real (positive)? If not, what type of deformation is suggested by the imaginary (negative) vibration?
Drugs / Pharmaceuticals |
Forensic Chemistry
Acids (GCMP)David M. Whisnant Acids: this is a resource in the collection "General Chemistry Multimedia Problems". We will observe the reaction of sodium bicarbonate with three acid solutions. General Chemistry Multimedia Problems ask students questions about experiments they see presented using videos and images. The questions asked apply concepts from different parts of an introductory course, encouraging students to decompartmentalize the material.
Acids / Bases
Acids and Salts (GCMP)David M. Whisnant Acids and Salts: this is a resource in the collection "General Chemistry Multimedia Problems". This problem will explore a few properties of common acids and their salts. General Chemistry Multimedia Problems ask students questions about experiments they see presented using videos and images. The questions asked apply concepts from different parts of an introductory course, encouraging students to decompartmentalize the material.
