A Chemist Looks at Nitrogen Monoxide Gas and Biological Signaling
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HIV-1 Protease: An Enzyme at Work This is "HIV-1 Protease: An Enzyme at Work", from a video tape published by the Journal of Chemical Education - Software as Special Issue 13
Real-World Topics: Medicinal ChemistryArrietta Clauss Instructors often look for real-world topics that interest students when designing labs and preparing lectures. The chemistry associated with drugs is a fertile area, and the archives of the Journal can be a resource for interesting drug-related activities to enhance student learning. Clauss, Arrietta. J. Chem. Educ.2008, 85, 1657.
Enrichment / Review Materials |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Applications of Chemistry
Receptor Surface Models in the Classroom: Introducing Molecular Modeling to Students in a 3-D WorldWerner J. Geldenhuys, Michael Hayes, Cornelis J. Van der Schyf, David D. Allen, and Sarel F. Malan Proposes a novel method for teaching drug interactions with a receptor, enzyme, or any other macromolecule or protein using plastic molecular models and aluminum foil. Geldenhuys, Werner J.; Hayes, Michael; Van der Schyf, Cornelis J.; Allen, David D.; Malan, Sarel F. J. Chem. Educ.2007, 84, 979.
Bioorganic Chemistry |
Drugs / Pharmaceuticals |
Laboratory Computing / Interfacing |
Medicinal Chemistry |
Molecular Modeling |
Enzymes
Molecular Handshake: Recognition through Weak Noncovalent InteractionsParvathi S. Murthy This article traces the development of our thinking about molecular recognition through noncovalent interactions, highlights their salient features, and suggests ways for comprehensive education on this important concept. Murthy, Parvathi S. J. Chem. Educ.2006, 83, 1010.
Nitric Oxide-Releasing CompoundsWilliam F. Coleman, Randall J. Wildman The five WebWare Molecules for December derive from the article Nitrogen-Based Diazeniumdiolates: Versatile Nitric Oxide-Releasing Compounds for Biomedical Research and Potential Clinical Applications by Joseph E. Saavedra and Larry K. Keefer.
Medicinal Chemistry
Prophine and ProtoporphyrinWilliam F. Coleman, Randall J. Wildman The WebWare molecules this month are from the article "Photochemotherapy: Light-Dependent Therapies in Medicine" by Edward P. Zovinka and Danielle R. Suneri. The first is a simple porphine, illustrating the ubiquitous four-nitrogen macrocycle, while the second is the protoporphyrin found in heme systems.
Medicinal Chemistry |
Photochemistry
Elements That Disintegrate Volume 03, issue 32 of a series of leaflets covering subjects of interest to students of elementary chemistry distributed in 1929 - 1932.