| Journal Articles: 82 results |
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Real-World Topics: Medicinal Chemistry Arrietta Clauss
Instructors often look for real-world topics that interest students when designing labs and preparing lectures. The chemistry associated with drugs is a fertile area, and the archives of the Journal can be a resource for interesting drug-related activities to enhance student learning.
Clauss, Arrietta. J. Chem. Educ. 2008, 85, 1657.
Enrichment / Review Materials |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Applications of Chemistry
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Receptor Surface Models in the Classroom: Introducing Molecular Modeling to Students in a 3-D World Werner J. Geldenhuys, Michael Hayes, Cornelis J. Van der Schyf, David D. Allen, and Sarel F. Malan
Proposes a novel method for teaching drug interactions with a receptor, enzyme, or any other macromolecule or protein using plastic molecular models and aluminum foil.
Geldenhuys, Werner J.; Hayes, Michael; Van der Schyf, Cornelis J.; Allen, David D.; Malan, Sarel F. J. Chem. Educ. 2007, 84, 979.
Bioorganic Chemistry |
Drugs / Pharmaceuticals |
Laboratory Computing / Interfacing |
Medicinal Chemistry |
Molecular Modeling |
Enzymes
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Molecular Handshake: Recognition through Weak Noncovalent Interactions Parvathi S. Murthy
This article traces the development of our thinking about molecular recognition through noncovalent interactions, highlights their salient features, and suggests ways for comprehensive education on this important concept.
Murthy, Parvathi S. J. Chem. Educ. 2006, 83, 1010.
Applications of Chemistry |
Biosignaling |
Membranes |
Molecular Recognition |
Noncovalent Interactions |
Chromatography |
Molecular Properties / Structure |
Polymerization |
Reactions
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Complexometric Titration of Aluminum and Magnesium Ions in Commercial Antacids. An Experiment for General and Analytical Chemistry Laboratories Shui-Ping Yang and Ruei-Ying Tsai
A novel experiment for determining the total and individual aluminum and magnesium ion content in commercial antacids is described. This experiment is developed with three independent protocols based on complexometric direct and back titrations containing the concepts and usages of blocking, masking, buffer controls and metallic indicators.
Yang, Shui-Ping; Tsai, Ruei-Ying. J. Chem. Educ. 2006, 83, 906.
Aqueous Solution Chemistry |
Chemometrics |
Consumer Chemistry |
Medicinal Chemistry |
Quantitative Analysis |
Titration / Volumetric Analysis |
UV-Vis Spectroscopy
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The Discovery and Development of Cisplatin Rebecca A. Alderden, Matthew D. Hall, and Trevor W. Hambley
Cisplatin is currently one of the most widely used anticancer drugs in the world. The unlikely events surrounding the discovery of its anticancer activity, subsequent introduction into the clinic, and the continuing research into platinum compounds is the subject of this review.
Alderden, Rebecca A.; Hall, Matthew D.; Hambley, Trevor W. J. Chem. Educ. 2006, 83, 728.
Bioinorganic Chemistry |
Coordination Compounds |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Metallic Bonding |
Oxidation State |
Synthesis
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Calcium Phosphates and Human Beings Sergey V. Dorozhkin
This article describes the general importance of calcium phosphates for human beings. The basic information on the structure and chemical properties of the biologically relevant calcium phosphates is summarized.
Dorozhkin, Sergey V. J. Chem. Educ. 2006, 83, 713.
Applications of Chemistry |
Bioinorganic Chemistry |
Biotechnology |
Materials Science |
Medicinal Chemistry |
Natural Products
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Stoichiometry of Calcium Medicines Gabriel Pinto
Calcium supplements provide an excellent context in which to review most of the core content of general chemistry, namely, stoichiometry, concentration units, hydration of salts, inorganic and organic salts, physiological importance of elements, resonance in ions, geometry of polyatomic ions, and isomerism.
Pinto, Gabriel. J. Chem. Educ. 2005, 82, 1509.
Stoichiometry |
Applications of Chemistry |
Drugs / Pharmaceuticals |
Medicinal Chemistry
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Based on a True Story: Using Movies as Source Material for General Chemistry Reports Mark A. Griep and Marjorie L. Mikasen
Presents a list of one dozen, highly rated movies in which the focus is either a scientist's chemical research or the societal impact of some chemical compound. The method by which two of these movies were used as source material for a written report in a general chemistry course is described.
Griep, Mark A.; Mikasen, Marjorie L. J. Chem. Educ. 2005, 82, 1501.
Medicinal Chemistry |
Women in Chemistry |
Applications of Chemistry |
Drugs / Pharmaceuticals |
Industrial Chemistry |
Nonmajor Courses |
Nuclear / Radiochemistry
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A Supramolecular Approach to Medicinal Chemistry: Medicine Beyond the Molecule David K. Smith
This article emphasizes a conceptual view of medicinal chemistry, which has important implications for the future, as the supramolecular approach to medicinal-chemistry products outlined here is rapidly allowing nanotechnology to converge with medicine. In particular, this article discusses recent developments including the rational design of drugs such as Relenza and Tamiflu, the mode of action of vancomycin, and the mechanism by which bacteria develop resistance, drug delivery using cyclodextrins, and the importance of supramolecular chemistry in understanding protein aggregation diseases such as Alzheimer's and CreutzfieldJacob.
Smith, David K. J. Chem. Educ. 2005, 82, 393.
Drugs / Pharmaceuticals |
Noncovalent Interactions |
Medicinal Chemistry |
Nanotechnology |
Proteins / Peptides
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Using Clinical Cases To Teach General Chemistry Brahmadeo Dewprashad, Charles Kosky, Geraldine S. Vaz, and Charlotte L. Martin
This article describes how a fact-based clinical case was effectively used to motivate and enrich the classroom experience and review many of the concepts covered in general chemistry. The case involves an elderly patient who was brought to the emergency room. The results of his physical examination and laboratory analysis of his blood are presented. The students, in peer-led groups, work through the chemical principles involved in the doctor's diagnosis and treatment options for the patient. The article describes the case study, instructors' observations, and students' perception of the activity.
Dewprashad, Brahmadeo; Kosky, Charles; Vaz, Geraldine S.; Martin, Charlotte L. J. Chem. Educ. 2004, 81, 1471.
Acids / Bases |
Drugs / Pharmaceuticals |
Equilibrium |
Kinetics |
Medicinal Chemistry
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Carbon Dioxide Flooding: A Classroom Case Study Derived from Surgical Practice Robert C. Kerber
The surgical opening in open-heart surgery is often flooded with carbon dioxide gas to avoid air embolisms when the heart is closed and restarted. This practice can be used in chemistry courses to illustrate concepts of gas density, solubility, and acidbase equilibria, including buffering.
Kerber, Robert C. . J. Chem. Educ. 2003, 80, 1437.
Acids / Bases |
Aqueous Solution Chemistry |
Gases |
Medicinal Chemistry |
Nonmajor Courses |
Applications of Chemistry
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An NMR-Smell Module for the First-Semester General Chemistry Laboratory Erich S. Uffelman, Elizabeth H. Cox, J. Brown Goehring, Tyler S. Lorig, and C. Michele Davis
The series of experiments involves an exploration of organic stereochemistry via hands-on model building, several chemosensory smell tests, and hands-on use of 13C NMR, thus serving as a powerful interdisciplinary lab involving chemistry, physics, and neuroscience. Similarities and differences between NMR and MRI methods are emphasized.
Uffelman, Erich S.; Cox, Elizabeth H.; Goehring, J. Brown; Lorig, Tyler S.; Davis, C. Michele. J. Chem. Educ. 2003, 80, 1368.
NMR Spectroscopy |
Stereochemistry |
Molecular Modeling |
Medicinal Chemistry
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Molecules, Miracles and Medicine
by Andrew Lasslo Peggy Geiger
Brief histories of morphine, procaine, aspirin, barbital, sulfanilamide, penicillin, valium, and cortisone.
Geiger, Peggy. J. Chem. Educ. 2002, 79, 805.
Drugs / Pharmaceuticals |
Medicinal Chemistry
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Drugs and the Human Body: With Implications for Society, 6th Edition
by Ken Liska David J. A. Schedler
Facts about drug sources, history, action in the body, side effects, interactions, tolerance, abuse potential, dosage, dependency, delivery systems, and alternatives to drug use.
Schedler, David J. A. J. Chem. Educ. 2002, 79, 805.
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Applications of Chemistry
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Modeling the Drug Discovery Process: The Isolation and Biological Testing of Eugenol from Clove Oil William H. Miles and Patricia M. Smiley
Experiment that illustrates the principles of modern drug discovery.
Miles, William H.; Smiley, Patricia M. J. Chem. Educ. 2002, 79, 90.
Acids / Bases |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Natural Products |
Separation Science |
Applications of Chemistry
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Blood-Chemistry Tutorials: Teaching Biological Applications of General Chemistry Material Rachel E. Casiday, Dewey Holten, Richard Krathen, and Regina F. Frey
Four, Web-based tutorials that deal with chemical processes in the blood and provide an integrated biological context for a variety of chemical concepts.
Casiday, Rachel E.; Holten, Dewey; Krathen, Richard; Frey, Regina F. J. Chem. Educ. 2001, 78, 1210.
Applications of Chemistry |
Medicinal Chemistry |
Proteins / Peptides |
Acids / Bases |
Equilibrium |
Molecular Properties / Structure
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Combinatorial Synthesis and Discovery of an Antibiotic Compound. An Experiment Suitable for High School and Undergraduate Laboratories Scott E. Wolkenberg and Andrew I. Su
An experiment designed to introduce students to combinatorial chemistry as applied to drug discovery.
Wolkenberg, Scott E.; Su, Andrew I. J. Chem. Educ. 2001, 78, 784.
Aqueous Solution Chemistry |
Bioorganic Chemistry |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Synthesis |
Combinatorial Chemistry |
Applications of Chemistry
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Two Faces of Alkaloids Jirí Dostál
The article discusses and compares the salts and free bases of six well-known alkaloids: nicotine, morphine, cocaine, sanguinarine, allocryptopine, and magnoflorine. Relevance for the biological and medical uses of these compounds is emphasized.
Dostál, Jirí. J. Chem. Educ. 2000, 77, 993.
Acids / Bases |
Bioorganic Chemistry |
Drugs / Pharmaceuticals |
Natural Products |
Aromatic Compounds |
Medicinal Chemistry
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Discovery and Early Uses of Iodine Louis Rosenfeld
Therapeutic use of iodine, particularly in prevention and treatment of goiter.
Rosenfeld, Louis. J. Chem. Educ. 2000, 77, 984.
Medicinal Chemistry |
Descriptive Chemistry |
Applications of Chemistry
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Synthesis of the Sweetener Dulcin from the Analgesic Tylenol Brian D. Williams, Birute Williams, and Louise Rodino
A sequence suitable for the synthesis of the sweetener dulcin from the analgesic acetaminophen. The analgesic phenacetin is isolated during the synthesis as an intermediate and consequently the experiment can be adopted as a multistep synthesis or as either of two single-period transformations.
Williams, Brian D.; Williams, Birute; Rodino, Louise. J. Chem. Educ. 2000, 77, 357.
Synthesis |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Aromatic Compounds
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Microwave Irradiation Reactions: Synthesis of Analgesic Drugs Gholam A. Mirafzal and Jolene M Summer
Over-the-counter analgesics such as aspirin, acetanilide, phenacetin, and acetaminophen are conveniently prepared in a microwave at 30% power for five minutes. Recrystallization from appropriate solvents results in solid products in good to excellent yields.
Mirafzal, Gholam A.; Summer, Jolene M. J. Chem. Educ. 2000, 77, 356.
Drugs / Pharmaceuticals |
Synthesis |
Medicinal Chemistry |
Aromatic Compounds |
Amines / Ammonium Compounds |
Esters
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Experiments with Aspirin Londa L. Borer and Edward Barry
Experiments include (i) synthesis, purification, and characterization of aspirin by mp and TLC, (ii) percentage composition of a commercial aspirin tablet by titration, (iii) kinetics of the hydrolysis of aspirin to salicylic acid under various conditions, (iv) synthesis and characterization of copper(II) aspirinate and copper(II) salicylate, and (v) reaction of copper(II) aspirinate in aqueous solution.
Borer, Londa L.; Barry, Edward. J. Chem. Educ. 2000, 77, 354.
Synthesis |
Kinetics |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Aromatic Compounds
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A Brine Shrimp Bioassay for Measuring Toxicity and Remediation of Chemicals Marya Lieberman
A bioassay using brine shrimp was adapted to measure the toxicity of household chemicals. One project is described in which students collect dose-response curves for seven commercial flea-killing products. Next, groups of students researched the insecticidal ingredients of the flea products. On the basis of the structures of the active ingredients, they chose remediation methods to make the flea product less toxic to brine shrimp; procedures included copper-catalyzed hydrolysis, adsorption onto activated charcoal, bleach treatment, and photodegradation.
Lieberman, Marya. J. Chem. Educ. 1999, 76, 1689.
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Nonmajor Courses |
Toxicology
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Henry's Law and Noisy Knuckles Doris R. Kimbrough
Presented here is the application of Henry's law to the noise associated with "cracking" knuckles. Gases dissolved in the synovial fluid in joints rapidly come out of solution as the joint is stretched and pressure is decreased. This "cavitation" produces a characteristic noise.
Kimbrough, Doris R. J. Chem. Educ. 1999, 76, 1509.
Gases |
Solutions / Solvents |
Applications of Chemistry |
Medicinal Chemistry
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The Chemical Adventures of Sherlock Holmes: The Death Puzzle at 221B Baker Street Thomas R. Rybolt and Thomas G. Waddell
A chemical mystery featuring Sherlock Holmes and Dr. Watson.
Rybolt, Thomas R.; Waddell, Thomas G. J. Chem. Educ. 1999, 76, 489.
Enrichment / Review Materials |
Aqueous Solution Chemistry |
Medicinal Chemistry |
Qualitative Analysis
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Enzyme-Linked Antibodies: A Laboratory Introduction to the ELISA Gretchen L. Anderson and Leo A. McNellis
A fast and economical laboratory exercise is presented that qualitatively demonstrates the power of enzyme-linked antibodies to detect a specific antigen. Although ELISAs are commonly used in disease diagnosis in clinical settings, this application uses biotin, covalently attached to albumin, to take advantage of readily available reagents and avoids problems associated with potentially pathogenic antigens.
Anderson, Gretchen L.; McNellis, Leo A. J. Chem. Educ. 1998, 75, 1275.
Enzymes |
Nonmajor Courses |
Medicinal Chemistry
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Production, Extraction, and Qualitative Testing of Penicillin: A Biochemistry Experiment for Health Science Chemistry Courses Richard E. Stevens and Kara C. Billingsley
This laboratory procedure guides students through the growth of a submerged Penicillium chrysogenum culture. Subsequent steps include extraction of the penicillin by adsorption onto activated charcoal, extraction with acetone, and qualitative testing of the drug on a bacterial culture. The laboratory procedure is designed for freshman-level health science chemistry courses.
Stevens, Richard E.; Billingsley, Kara C. J. Chem. Educ. 1998, 75, 1264.
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Nonmajor Courses
|
Synthesis of Aspirin: A General Chemistry Experiment John A. Olmsted III
An experiment is described that is suitable for the early portion of the laboratory in a general chemistry course and integrates organic examples. It is the two-step synthesis of aspirin starting from oil of wintergreen. The mechanism for this synthesis provides examples of three major classes of chemical reactions: hydrolysis, condensation, and proton transfer.
Olmsted, John A., III. J. Chem. Educ. 1998, 75, 1261.
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Mechanisms of Reactions |
Aromatic Compounds |
Carboxylic Acids |
Aldehydes / Ketones
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The Art and Science of Organic and Natural Products Synthesis K. C. Nicolaou, E. J. Sorensen, and N. Winssinger
In this article, the history of the art and science of organic and natural products synthesis is briefly reviewed and the state of the art is discussed. The impact of this discipline on biology and medicine is amply demonstrated with examples, and projections for future developments in the field are made.
Nicolaou, K. C.; Sorensen, E. J.; Winssinger, N. J. Chem. Educ. 1998, 75, 1225.
Natural Products |
Synthesis |
Medicinal Chemistry |
Applications of Chemistry |
Drugs / Pharmaceuticals
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Vanillin (the author replies) Hocking, Martin
Additional information regarding salicylic acid.
Hocking, Martin J. Chem. Educ. 1998, 75, 1203.
Aldehydes / Ketones |
Applications of Chemistry |
Medicinal Chemistry |
Molecular Properties / Structure
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Vanillin Calloway, Dean
Incorrect structural formula for methyl salicylate.
Calloway, Dean J. Chem. Educ. 1998, 75, 1203.
Medicinal Chemistry |
Applications of Chemistry |
Aldehydes / Ketones |
Molecular Properties / Structure
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Letters
Incorrect structural formula for methyl salicylate.
J. Chem. Educ. 1998, 75, 1203.
Medicinal Chemistry |
Applications of Chemistry |
Aldehydes / Ketones |
Molecular Properties / Structure
|
Fundamentals of General, Organic and Biological Chemistry, 2nd ed. by John McMurry and Mary E. Castellion Lois B. Krause
This text, mainly intended as a general chemistry text for students in health or life science related majors, does a beautiful job of incorporating topics and examples to which students can relate.
Krause, Lois B. J. Chem. Educ. 1997, 74, 1279.
Medicinal Chemistry
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Introduction to General, Organic and Biological Chemistry by Michael S. Matta, Antony C. Wilbraham, and Dennis D. Staley Lois B. Krause
Intended specifically for undergraduate majors in health sciences, the primary aim of this text is to prepare students to understand the chemistry of the living cell.
Krause, Lois B. J. Chem. Educ. 1997, 74, 1277.
Medicinal Chemistry
|
What Do College Students Know About Illegal Drugs? Christine K. F. Hermann
Survey of student understanding of illegal drugs.
Hermann, Christine K. F. J. Chem. Educ. 1995, 72, 925.
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Enrichment / Review Materials
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Chemistry for the Health Sciences, Seventh Edition (Sackheim, George I.; Lehman, Dennis D.) Jache, Albert W.
Emphasis is placed on practical aspects of inorganic, organic, and biochemistry; theoretic topics are dealt with only as an aid to try to understand human bodily processes.
Jache, Albert W. J. Chem. Educ. 1994, 71, A132.
Nonmajor Courses |
Medicinal Chemistry
|
Risks and Chemical Substances Blumberg, Avrom A.
We are exposed to about 50 thousand of the 12 million different substances that chemists have identified. This paper looks at how we become exposed within our homes, examine three important ways in which we identify and evaluate hazardous substances, and try to suggest a rational picture of the risks we face.
Blumberg, Avrom A. J. Chem. Educ. 1994, 71, 912.
Medicinal Chemistry
|
An Attack on the AIDS Virus: Inhibition of the HIV-1 Protease. New Drug Development Based on the Structure and Activity of the Protease and its Role in the Replication and Maturation of the Virus Volker, Eugene J.
Article shows how research into the biochemistry of HIV may lead to a method for controlling its growth and maturation. This research illustrates some basic enzyme chemistry and holds student appeal due to the tie into current affairs.
Volker, Eugene J. J. Chem. Educ. 1993, 70, 3.
Bioorganic Chemistry |
Proteins / Peptides |
Medicinal Chemistry |
Molecular Biology
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Phenol and the importance of dose. Crute, Thomas D.
Phenol is highly toxic, but the active ingredient in Chloraseptic lozenges.
Crute, Thomas D. J. Chem. Educ. 1992, 69, 553.
Phenols |
Aromatic Compounds |
Alcohols |
Toxicology |
Consumer Chemistry |
Medicinal Chemistry
|
Views of nursing professionals on chemistry course content for nursing education Walhout, Justine S.; Heinschel, Judie.
Analysis of survey conducted of deans of schools of nursing, chairs of nursing departments, and registered nurses regarding courses required of nursing students and the importance of different units of measure and 39 chemistry topics to the nursing profession.
Walhout, Justine S.; Heinschel, Judie. J. Chem. Educ. 1992, 69, 483.
Medicinal Chemistry |
Nomenclature / Units / Symbols
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Advice from Allied Health faculty to chemistry faculty Dever, David F.
Finding out what the different health professions would like to see from undergraduate chemistry programs.
Dever, David F. J. Chem. Educ. 1991, 68, 763.
Medicinal Chemistry |
Nuclear / Radiochemistry |
Nutrition |
Vitamins |
Gases
|
College Chemistry Faculties, Eighth Edition (Talmadge, Cornelia A., editor) Kauffman, George B.
This book is a directory of two-year college, four-year college, and university teachers of chemistry, biochemistry, medicinal/pharmaceutical chemistry, and chemical engineering in the United States and Canada.
Kauffman, George B. J. Chem. Educ. 1990, 67, A151.
Medicinal Chemistry |
Administrative Issues
|
American Chemical Society Directory of Graduate Research, 1987 (The ACS Committee on Professional Training) Kauffman, George B.
This latest edition contains a wealth of information on 668 universities and colleges in the United States and Canada that offer bachelor's and master's curricula in chemistry; chemical engineering; pharmaceutical and medicinal chemistry; clinical chemistry; and polymer science.
Kauffman, George B. J. Chem. Educ. 1989, 66, A47.
Medicinal Chemistry
|
Teaching the skills of science - gold and anemia Mattson, William
A student poses a question that leads to classroom inquiry: Why does gold rubbed on the face of an anemic person leave a dark mark?
Mattson, William J. Chem. Educ. 1988, 65, 1000.
Bioinorganic Chemistry |
Medicinal Chemistry |
Applications of Chemistry
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Oxalate blockage of calcium and iron: A student learning activity Walker, Noojin
The topics of iron deficiency anemia and osteoporosis entice student attention and can be used to construct meaningful learning activities about percent composition, mole concept, selective precipitation, and limiting factors.
Walker, Noojin J. Chem. Educ. 1988, 65, 533.
Medicinal Chemistry |
Stoichiometry |
Plant Chemistry |
Bioanalytical Chemistry |
Bioinorganic Chemistry
|
Determining the solubility of Ca(OH)2 using 45Ca as a tracer Edmiston, Michael D.; Suter, Robert W.
These authors have developed a simple lab that can be incorporated into freshman chemistry that allows students to understand the power of radiochemistry as an analytical tool as well as gain perspectives about real versus imagined dangers of radioactivity.
Edmiston, Michael D.; Suter, Robert W. J. Chem. Educ. 1988, 65, 279.
Nuclear / Radiochemistry |
Medicinal Chemistry
|
General, Organic & Biological Chemistry, Study Guide and Solutions Manual (Feigl, Dorothy M.; Hill, John W.) Taylor, R. Craig
Written for students in the health and life science and intended for students who have had little or no chemistry background.
Taylor, R. Craig J. Chem. Educ. 1987, 64, A327.
Nonmajor Courses |
Medicinal Chemistry
|
Chemistry for the allied health students Williams, Donald H.
Review of the recent educational literature regarding chemistry for allied health students; includes a suggested outline for a year-long course.
Williams, Donald H. J. Chem. Educ. 1987, 64, 707.
Nonmajor Courses |
Medicinal Chemistry
|
A syllabus for a two-semester chemistry course for health professions: Report of the committee on chemical education for the health professions Daly, John M.; Sarquis, Jerry L.
Outline of a two-semester chemistry course for health professions.
Daly, John M.; Sarquis, Jerry L. J. Chem. Educ. 1987, 64, 699.
Nonmajor Courses |
Medicinal Chemistry
|
Hemoglobinometry: A biochemistry experiment that utilizes the principles of transition metal chemistry Giuliano, Vincenzo
Colorimetric measurements are used to determine the concentration of hemoglobin in blood and the effect of the effect that the presence of cyanide ions has on the formation of cyanomethemoglobin.
Giuliano, Vincenzo J. Chem. Educ. 1987, 64, 354.
Transition Elements |
Metals |
Medicinal Chemistry |
Spectroscopy
|
Consumer applications of chemical principles: Drugs Hill, John W.; Jones, Susan M.
Acid-base chemistry of drugs (nicotine, cocaine, and aspirin), general anesthesia (nitrous oxide, enflurane, isoflurane, halothane), local anesthetics (procaine, lidocaine, cocaine), and intravenous anesthetics (thiopental, ketamine hydrochloride, phencyclidine).
Hill, John W.; Jones, Susan M. J. Chem. Educ. 1985, 62, 328.
Consumer Chemistry |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Acids / Bases |
Applications of Chemistry
|
Drug stabilization against oxidative degradation Akers, Michael J.
Describes the process of oxidation and ways in which pharmaceutical preparations can be protected from oxidative degredation.
Akers, Michael J. J. Chem. Educ. 1985, 62, 325.
Drugs / Pharmaceuticals |
Oxidation / Reduction |
Medicinal Chemistry |
Nonmajor Courses
|
Organic chemistry for health-science students (the authors reply) Genyea, Julien; Callewaert, Denis
Importance of time limitations in teaching general, organic, and biochemistry in a two-semester course.
Genyea, Julien; Callewaert, Denis J. Chem. Educ. 1985, 62, 272.
Medicinal Chemistry |
Nonmajor Courses
|
Organic chemistry for health-science students Schumm, Margot K.
It is important to teach health-science students reaction mechanisms when teaching them organic and biochemistry.
Schumm, Margot K. J. Chem. Educ. 1985, 62, 272.
Medicinal Chemistry |
Nonmajor Courses |
Mechanisms of Reactions
|
Chemistry instruction using evening news video tape segments Greenberg, Fred G.
Evening newscasts often provide current, dramatic, and meaningful applications of basic chemical principles.
Greenberg, Fred G. J. Chem. Educ. 1985, 62, 227.
Medicinal Chemistry |
Applications of Chemistry
|
Chemistry for Health-Related Sciences; Concepts and Correlations, Second Edition (Sears, Curtis T.; Stanitski, Conrad L.) Meloy, Carl R.
Designed for a two-term chemistry course for students in health-related programs.
Meloy, Carl R. J. Chem. Educ. 1984, 61, A221.
Noncovalent Interactions |
Medicinal Chemistry
|
A syllabus for a one semester chemistry course for health professions: Report of the Task Force on Chemical Education for Health Professions Treblow, Mordecai; Daly, John M.; Sarquis, Jerry L.
Goals and outline of topics for a one semester chemistry course for health professions.
Treblow, Mordecai; Daly, John M.; Sarquis, Jerry L. J. Chem. Educ. 1984, 61, 620.
Medicinal Chemistry |
Nonmajor Courses
|
Chemistry for health-science students: what is an appropriate balance between basic chemical concepts and health-related applications? Genyea, Julien; Callewaert, Denis M.
The curricular suggestions made in this paper stem from the authors' experience developing, and teaching, a sequence of chemistry courses to meet the needs of nursing students. It is believed that these suggestions apply equally well for students who intend to pursue professional careers in other health-science areas.
Genyea, Julien; Callewaert, Denis M. J. Chem. Educ. 1983, 60, 471.
Nonmajor Courses |
Medicinal Chemistry
|
General, Organic and Biochemistry (Brown, William H.; Rogers, Elizabeth) Haag, William L.
Directed toward those interested in the health sciences.
Haag, William L. J. Chem. Educ. 1982, 59, A64.
Nonmajor Courses |
Medicinal Chemistry
|
Chemistry for the Health Professions (Henrickson, Charles H.; Byrd, L. C.) Laughlin, Etheireda
A one-year chemistry text for a variety of paramedical programs.
Laughlin, Etheireda J. Chem. Educ. 1982, 59, A26.
Nonmajor Courses |
Medicinal Chemistry
|
On the use of intravenous solutions to teach some principles of solution chemistry Shapiro, Irwin L.
A series of laboratory periods are devoted to the chemistry of intravenous solution in a one-semeter course for nursing students.
Shapiro, Irwin L. J. Chem. Educ. 1982, 59, 725.
Solutions / Solvents |
Nonmajor Courses |
Medicinal Chemistry
|
Some aspects of coordination chemistry Mickey, Charles D.
The genesis of modern coordination theory; the Wernerian system; experimental support for Werner's coordination theory; amplification of Werner's theory; the nature of complex ions; formation and nomenclature for complexes, complexes in the environment; chelates in medicine; complexing in natural systems; and industrial application of complexes.
Mickey, Charles D. J. Chem. Educ. 1981, 58, 257.
Coordination Compounds |
Medicinal Chemistry |
Metals
|
Magical sand Smith, Douglas D.
Smith, Douglas D. J. Chem. Educ. 1980, 57, 363.
Applications of Chemistry |
Medicinal Chemistry
|
Drugs in the chemistry laboratory: The conversion of acetaminophen into phenacetin Volker, Eugene J.; Pride, Ernest; Hough, Charles
The phenolic alcohol group of acetaminophen is alkylated with ethyl iodide using the basic catalyst K2CO3.
Volker, Eugene J.; Pride, Ernest; Hough, Charles J. Chem. Educ. 1979, 56, 831.
Nonmajor Courses |
Applications of Chemistry |
Medicinal Chemistry |
Drugs / Pharmaceuticals |
Synthesis |
Catalysis |
Phenols |
Alcohols
|
Some biochemistry of sedatives J. Chem. Educ. Staff
Antianxiety agents / sleep reducers, the discovery of sedatives and their chemistry, and biological responses to sedatives.
J. Chem. Educ. Staff J. Chem. Educ. 1979, 56, 402.
Drugs / Pharmaceuticals |
Applications of Chemistry |
Medicinal Chemistry
|
Medicinal chemistry of aspirin and related drugs J. Chem. Educ. Staff
Nonprescription analgesics, the discovery of aspirin, pain and analgesic activity, inflammation and the role of chemical agents, fever and its reduction, aspirin in stroke prevention, and toxicity and side effects.
J. Chem. Educ. Staff J. Chem. Educ. 1979, 56, 331.
Applications of Chemistry |
Medicinal Chemistry |
Drugs / Pharmaceuticals |
Toxicology
|
Thin layer chromatographic separation of common analgesics - A consumer experiment Cormier, Russell A.; Hudson, William B.; Siegel, Jay A.
A simple method for determining which analgesics have which ingredients.
Cormier, Russell A.; Hudson, William B.; Siegel, Jay A. J. Chem. Educ. 1979, 56, 180.
Consumer Chemistry |
Chromatography |
Separation Science |
Medicinal Chemistry |
Qualitative Analysis
|
Copper(II) aspirinate project for the general chemistry laboratory Dudek, Emily
The weight percent of copper in student-prepared copper(II) aspirinate is measured by electrogravimetric, spectrophotometric, and titrimetric methods.
Dudek, Emily J. Chem. Educ. 1977, 54, 329.
Titration / Volumetric Analysis |
Medicinal Chemistry |
Drugs / Pharmaceuticals |
Synthesis |
Quantitative Analysis
|
The effects of HCl and aspirin on the stomach: An equilibrium review DeLorenzo, Ronald
The chemical effect and medical implications of taking aspirin.
DeLorenzo, Ronald J. Chem. Educ. 1977, 54, 306.
Equilibrium |
Acids / Bases |
pH |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Applications of Chemistry
|
Questions [and] Answers Campbell, J. A.
290-297. Eight questions regarding practical applications of chemistry, primarily in the medical field, and their answers.
Campbell, J. A. J. Chem. Educ. 1977, 54, 247.
Toxicology |
Equilibrium |
Metabolism |
Medicinal Chemistry |
Applications of Chemistry |
Enrichment / Review Materials
|
Questions [and] Answers Campbell, J. A.
284-289. Six questions and their answers on practical applications of chemistry.
Campbell, J. A. J. Chem. Educ. 1977, 54, 161.
Medicinal Chemistry |
Enzymes |
Nuclear / Radiochemistry |
Drugs / Pharmaceuticals |
Applications of Chemistry |
Enrichment / Review Materials
|
Some iron anecdotes Ainscough, E. W.; Brodie, A. M.
When introducing the bioinorganic chemistry of iron, this anecdote can be use to illustrate one of the earliest applications of iron therapy (1500 B.C.).
Ainscough, E. W.; Brodie, A. M. J. Chem. Educ. 1976, 53, 646.
Bioinorganic Chemistry |
Medicinal Chemistry
|
Minicourses in chemistry Lygre, D. G.; Hasbrouck, R. W.; Gaines, R. D.; Duncan, L. C.; Habib, H. S.; Meany, J. E.; Newschwander, W. W.
Briefly describes a variety of minicourses designed to acquaint students with practical applications of chemistry in everyday experiences.
Lygre, D. G.; Hasbrouck, R. W.; Gaines, R. D.; Duncan, L. C.; Habib, H. S.; Meany, J. E.; Newschwander, W. W. J. Chem. Educ. 1975, 52, 735.
Consumer Chemistry |
Medicinal Chemistry |
Nuclear / Radiochemistry |
Plant Chemistry |
Agricultural Chemistry |
Applications of Chemistry |
Food Science
|
A new chemistry program for nursing and allied health students Stanitski, Conrad L.; Sears, Curtis T., Jr.
Outlines and discusses the topics considered in a chemistry program for nursing and allied health students.
Stanitski, Conrad L.; Sears, Curtis T., Jr. J. Chem. Educ. 1975, 52, 226.
Nonmajor Courses |
Applications of Chemistry |
Medicinal Chemistry |
Oxidation / Reduction |
Catalysis |
Acids / Bases |
pH |
Metabolism |
Drugs / Pharmaceuticals
|
An audio-tutorial program in allied health chemistry Laughlin, Ethelreda; Kurnath, Norbert
Describes the nature and use of an audio-tutorial program in allied health chemistry.
Laughlin, Ethelreda; Kurnath, Norbert J. Chem. Educ. 1975, 52, 75.
Nonmajor Courses |
Medicinal Chemistry
|
New directions for the traditional curriculum. Session III-A: Chemistry for the preprofessional students Plumb, Robert C.; Whidden, Helen L.; Davis, Fred W.
Freshman chemistry for engineers; biology majors in the general chemistry course; undergraduate organic chemistry; chemical concepts in allied health; and chemistry for nursing majors.
Plumb, Robert C.; Whidden, Helen L.; Davis, Fred W. J. Chem. Educ. 1973, 50, 23.
Conferences |
Professional Development |
Nonmajor Courses |
Medicinal Chemistry
|
Pain: A chemical explanation Plumb, Robert C.; Lindahl, Olov
In sensing pain the nervous system acts like a pH meter.
Plumb, Robert C.; Lindahl, Olov J. Chem. Educ. 1972, 49, 179.
pH |
Acids / Bases |
Applications of Chemistry |
Medicinal Chemistry
|
Sickle-cell anemia, hemoglobin solubility and resistance to malaria Martin, David L.; Huheey, James E.
The phenomenon of erythrocytic sickling is of considerable pedagogical usefulness since it provides a bridge of relevance between chemistry and biology.
Martin, David L.; Huheey, James E. J. Chem. Educ. 1972, 49, 177.
Proteins / Peptides |
Medicinal Chemistry |
Applications of Chemistry
|
Beer, acetone, and diabetes: A story and a demonstration Isenberg, Norbert
Acetone causes the collapse of beer foam.
Isenberg, Norbert J. Chem. Educ. 1972, 49, 151.
Aldehydes / Ketones |
Medicinal Chemistry
|
Chemistry for the Health Sciences (Sackheim, George I.; Schultz, Ronald M.) Caraway, Kathryn, P.
Caraway, Kathryn, P. J. Chem. Educ. 1969, 46, 702.
Medicinal Chemistry |
Nonmajor Courses
|
To the editor Boig, Fletcher S.
We do non-chemistry majors a serious disservice by attempting to make career chemists of them.
Boig, Fletcher S. J. Chem. Educ. 1968, 45, 813.
Nonmajor Courses |
Medicinal Chemistry
|
AlkaloidsThe world's pain killers Ray, R. L.
Examines the history and properties of the alkaloids, including morphine, strychnine, and curare.
Ray, R. L. J. Chem. Educ. 1960, 37, 451.
Medicinal Chemistry
|
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