TIGER

Journal Articles: 11 results
A Colorimetric Analysis Experiment Not Requiring a Spectrophotometer: Quantitative Determination of Albumin in Powdered Egg White  Amanda K. Charlton, Richard S. Sevcik, Dorie A. Tucker, and Linda D. Schultz
Albumin in powdered egg white is reacted with bromophenol blue, and the resulting blue color is compared to that formed by an albumin standard using a visual comparator method.
Charlton, Amanda K.; Sevcik, Richard S.; Tucker, Dorie A.; Schultz, Linda D. J. Chem. Educ. 2007, 84, 826.
Bioanalytical Chemistry |
Dyes / Pigments |
Proteins / Peptides |
Quantitative Analysis
An NMR-Smell Module for the First-Semester General Chemistry Laboratory  Erich S. Uffelman, Elizabeth H. Cox, J. Brown Goehring, Tyler S. Lorig, and C. Michele Davis
The series of experiments involves an exploration of organic stereochemistry via hands-on model building, several chemosensory smell tests, and hands-on use of 13C NMR, thus serving as a powerful interdisciplinary lab involving chemistry, physics, and neuroscience. Similarities and differences between NMR and MRI methods are emphasized.
Uffelman, Erich S.; Cox, Elizabeth H.; Goehring, J. Brown; Lorig, Tyler S.; Davis, C. Michele. J. Chem. Educ. 2003, 80, 1368.
NMR Spectroscopy |
Stereochemistry |
Molecular Modeling |
Medicinal Chemistry
Drugs and the Human Body: With Implications for Society, 6th Edition
   by Ken Liska
  David J. A. Schedler
Facts about drug sources, history, action in the body, side effects, interactions, tolerance, abuse potential, dosage, dependency, delivery systems, and alternatives to drug use.
Schedler, David J. A. J. Chem. Educ. 2002, 79, 805.
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Applications of Chemistry
Combinatorial Synthesis and Discovery of an Antibiotic Compound. An Experiment Suitable for High School and Undergraduate Laboratories  Scott E. Wolkenberg and Andrew I. Su
An experiment designed to introduce students to combinatorial chemistry as applied to drug discovery.
Wolkenberg, Scott E.; Su, Andrew I. J. Chem. Educ. 2001, 78, 784.
Aqueous Solution Chemistry |
Bioorganic Chemistry |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Synthesis |
Combinatorial Chemistry |
Applications of Chemistry
Enzyme-Linked Antibodies: A Laboratory Introduction to the ELISA  Gretchen L. Anderson and Leo A. McNellis
A fast and economical laboratory exercise is presented that qualitatively demonstrates the power of enzyme-linked antibodies to detect a specific antigen. Although ELISAs are commonly used in disease diagnosis in clinical settings, this application uses biotin, covalently attached to albumin, to take advantage of readily available reagents and avoids problems associated with potentially pathogenic antigens.
Anderson, Gretchen L.; McNellis, Leo A. J. Chem. Educ. 1998, 75, 1275.
Enzymes |
Nonmajor Courses |
Medicinal Chemistry
Synthesis of Aspirin: A General Chemistry Experiment  John A. Olmsted III
An experiment is described that is suitable for the early portion of the laboratory in a general chemistry course and integrates organic examples. It is the two-step synthesis of aspirin starting from oil of wintergreen. The mechanism for this synthesis provides examples of three major classes of chemical reactions: hydrolysis, condensation, and proton transfer.
Olmsted, John A., III. J. Chem. Educ. 1998, 75, 1261.
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Mechanisms of Reactions |
Aromatic Compounds |
Carboxylic Acids |
Aldehydes / Ketones
Risks and Chemical Substances  Blumberg, Avrom A.
We are exposed to about 50 thousand of the 12 million different substances that chemists have identified. This paper looks at how we become exposed within our homes, examine three important ways in which we identify and evaluate hazardous substances, and try to suggest a rational picture of the risks we face.
Blumberg, Avrom A. J. Chem. Educ. 1994, 71, 912.
Medicinal Chemistry
An Attack on the AIDS Virus: Inhibition of the HIV-1 Protease. New Drug Development Based on the Structure and Activity of the Protease and its Role in the Replication and Maturation of the Virus  Volker, Eugene J.
Article shows how research into the biochemistry of HIV may lead to a method for controlling its growth and maturation. This research illustrates some basic enzyme chemistry and holds student appeal due to the tie into current affairs.
Volker, Eugene J. J. Chem. Educ. 1993, 70, 3.
Bioorganic Chemistry |
Proteins / Peptides |
Medicinal Chemistry |
Molecular Biology
Views of nursing professionals on chemistry course content for nursing education  Walhout, Justine S.; Heinschel, Judie.
Analysis of survey conducted of deans of schools of nursing, chairs of nursing departments, and registered nurses regarding courses required of nursing students and the importance of different units of measure and 39 chemistry topics to the nursing profession.
Walhout, Justine S.; Heinschel, Judie. J. Chem. Educ. 1992, 69, 483.
Medicinal Chemistry |
Nomenclature / Units / Symbols
Analogical demonstrations   Fortman, John J.
By illustrating an analogy with a visual demonstration, a student is aided in both understanding and remembering a lesson.
Fortman, John J. J. Chem. Educ. 1992, 69, 323.
Physical Properties |
Atomic Properties / Structure |
Amino Acids |
Proteins / Peptides |
Acids / Bases
New directions for the traditional curriculum. Session III-A: Chemistry for the preprofessional students  Plumb, Robert C.; Whidden, Helen L.; Davis, Fred W.
Freshman chemistry for engineers; biology majors in the general chemistry course; undergraduate organic chemistry; chemical concepts in allied health; and chemistry for nursing majors.
Plumb, Robert C.; Whidden, Helen L.; Davis, Fred W. J. Chem. Educ. 1973, 50, 23.
Conferences |
Professional Development |
Nonmajor Courses |
Medicinal Chemistry