TIGER

Journal Articles: 9 results
Gifts from Mother Earth—The Good, the Bad, and the Ugly  Sabine Heinhorst and Gordon C. Cannon
Recent articles from the journal Nature that deal with good, bad, and ugly gifts from Mother Earth are described.
Heinhorst, Sabine; Cannon, Gordon C. J. Chem. Educ. 2006, 83, 196.
Biosynthesis |
Biotechnology |
Natural Products |
Nutrition |
Plant Chemistry |
Polymerization |
Proteins / Peptides
Based on a True Story: Using Movies as Source Material for General Chemistry Reports  Mark A. Griep and Marjorie L. Mikasen
Presents a list of one dozen, highly rated movies in which the focus is either a scientist's chemical research or the societal impact of some chemical compound. The method by which two of these movies were used as source material for a written report in a general chemistry course is described.
Griep, Mark A.; Mikasen, Marjorie L. J. Chem. Educ. 2005, 82, 1501.
Medicinal Chemistry |
Women in Chemistry |
Applications of Chemistry |
Drugs / Pharmaceuticals |
Industrial Chemistry |
Nonmajor Courses |
Nuclear / Radiochemistry
Experiments with Aspirin  Londa L. Borer and Edward Barry
Experiments include (i) synthesis, purification, and characterization of aspirin by mp and TLC, (ii) percentage composition of a commercial aspirin tablet by titration, (iii) kinetics of the hydrolysis of aspirin to salicylic acid under various conditions, (iv) synthesis and characterization of copper(II) aspirinate and copper(II) salicylate, and (v) reaction of copper(II) aspirinate in aqueous solution.
Borer, Londa L.; Barry, Edward. J. Chem. Educ. 2000, 77, 354.
Synthesis |
Kinetics |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Aromatic Compounds
Enzyme-Linked Antibodies: A Laboratory Introduction to the ELISA  Gretchen L. Anderson and Leo A. McNellis
A fast and economical laboratory exercise is presented that qualitatively demonstrates the power of enzyme-linked antibodies to detect a specific antigen. Although ELISAs are commonly used in disease diagnosis in clinical settings, this application uses biotin, covalently attached to albumin, to take advantage of readily available reagents and avoids problems associated with potentially pathogenic antigens.
Anderson, Gretchen L.; McNellis, Leo A. J. Chem. Educ. 1998, 75, 1275.
Enzymes |
Nonmajor Courses |
Medicinal Chemistry
The Art and Science of Organic and Natural Products Synthesis  K. C. Nicolaou, E. J. Sorensen, and N. Winssinger
In this article, the history of the art and science of organic and natural products synthesis is briefly reviewed and the state of the art is discussed. The impact of this discipline on biology and medicine is amply demonstrated with examples, and projections for future developments in the field are made.
Nicolaou, K. C.; Sorensen, E. J.; Winssinger, N. J. Chem. Educ. 1998, 75, 1225.
Natural Products |
Synthesis |
Medicinal Chemistry |
Applications of Chemistry |
Drugs / Pharmaceuticals
Risks and Chemical Substances  Blumberg, Avrom A.
We are exposed to about 50 thousand of the 12 million different substances that chemists have identified. This paper looks at how we become exposed within our homes, examine three important ways in which we identify and evaluate hazardous substances, and try to suggest a rational picture of the risks we face.
Blumberg, Avrom A. J. Chem. Educ. 1994, 71, 912.
Medicinal Chemistry
An Attack on the AIDS Virus: Inhibition of the HIV-1 Protease. New Drug Development Based on the Structure and Activity of the Protease and its Role in the Replication and Maturation of the Virus  Volker, Eugene J.
Article shows how research into the biochemistry of HIV may lead to a method for controlling its growth and maturation. This research illustrates some basic enzyme chemistry and holds student appeal due to the tie into current affairs.
Volker, Eugene J. J. Chem. Educ. 1993, 70, 3.
Bioorganic Chemistry |
Proteins / Peptides |
Medicinal Chemistry |
Molecular Biology
The chemical composition of the cell  Holum, John R.
A broad outline of the chemical substances that occur in most cells.
Holum, John R. J. Chem. Educ. 1984, 61, 877.
Biological Cells |
Lipids |
Carbohydrates |
Proteins / Peptides
Non-covalent interactions: Key to biological flexibility and specificity  Frieden, Earl
Summarizes the types of non-covalent interactions found among biomolecules and how they facilitate the function of antibodies, hormones, and hemoglobin.
Frieden, Earl J. Chem. Educ. 1975, 52, 754.
Noncovalent Interactions |
Hydrogen Bonding |
Water / Water Chemistry |
Proteins / Peptides |
Amino Acids |
Molecular Properties / Structure |
Hormones