23.3. What Is the Terminology Used with Enzymes?, 618
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Halting the Briggs-Rauscher Oscillating Reaction The Briggs-Rauscher reaction is demonstrated in three different ways. Catalase from a liver extract decomposes the hydrogen peroxide in an Briggs-Rauscher reaction, stopping the oscillations.
Catalysis |
Kinetics |
Enzymes |
Proteins / Peptides
HIV-1 Protease: An Enzyme at Work This is "HIV-1 Protease: An Enzyme at Work", from a video tape published by the Journal of Chemical Education - Software as Special Issue 13
Biochemistry : Inhibitor (15 Variations) Which of the following molecules would you expect to be the strongest competitive inhibitor of the enzyme whose substrate is shown?
alcohol dehydrogenase, substrate ethanol CH2CH2OH
Enzymes
Kinetics : Enzyme (7 Variations)
Trypsin assists in digestion by breaking proteins down into smaller peptides. However, this process is not as efficient in the presence of fluorophosphates. Identify the role of each of these components.
Enzymes |
Kinetics
Journal Articles: First 3 results.
Pedagogies:
OMLeT—An Alternative Approach to Learning Metabolism: Glycolysis and the TCA Cycle as an ExampleCharles M. Stevens, Dylan M. Silver, Brad Behm, Raymond J. Turner, and Michael G. Surette Using PHP Hypertext Preprocessor scripting, the dynamic OMLeT (Online Metabolism Learning Tool) Web site is geared towards different learning styles and allows the student to process metabolic pathways (glycolysis and TCA cycle) via a user-defined approach. Stevens, Charles M.; Silver, Dylan M.; Behm, Brad; Turner, Raymond J.; Surette, Michael G. J. Chem. Educ.2007, 84, 2024.
Bioenergetics |
Enzymes |
Learning Theories |
Metabolism |
Proteins / Peptides
Receptor Surface Models in the Classroom: Introducing Molecular Modeling to Students in a 3-D WorldWerner J. Geldenhuys, Michael Hayes, Cornelis J. Van der Schyf, David D. Allen, and Sarel F. Malan Proposes a novel method for teaching drug interactions with a receptor, enzyme, or any other macromolecule or protein using plastic molecular models and aluminum foil. Geldenhuys, Werner J.; Hayes, Michael; Van der Schyf, Cornelis J.; Allen, David D.; Malan, Sarel F. J. Chem. Educ.2007, 84, 979.
Bioorganic Chemistry |
Drugs / Pharmaceuticals |
Laboratory Computing / Interfacing |
Medicinal Chemistry |
Molecular Modeling |
Enzymes
Kinetics of Alcohol Dehydrogenase-Catalyzed Oxidation of Ethanol Followed by Visible SpectroscopyKestutis Bendinskas, Christopher DiJiacomo, Allison Krill, and Ed Vitz A two-week biochemistry experiment was introduced in the second-semester general chemistry laboratory to study the oxidation of ethanol in vitro in the presence of the enzyme alcohol dehydrogenase (ADH). This reaction should pique student interest because the same reaction also occurs in human bodies when alcoholic drinks are consumed. Procedures were developed to follow the biochemical reaction by visible spectroscopy and to avoid specialized equipment. The effect of substrate concentration on the rate of this enzymatic reaction was investigated during the first week. The effects of temperature, pH, the specificity of the enzyme to several substrates, and the enzyme's inhibition by heavy metals were explored during the second week. Bendinskas, Kestutis; DiJiacomo, Christopher; Krill, Allison; Vitz, Ed. J. Chem. Educ.2005, 82, 1068.
Enzyme Activity as a Function of pHPaul Krause A matched pair of documents providing an introduction to the role of pH in the regulation of enzyme activity. The tutorial document contains all the equations and graphs for students to use to study the role of pH in enzyme kinetics. In the EnzymeExercise twin document all quations are omitted so that students can develop these interactively. The Exercise document is also ideal for display during lecture where the ideas can be developed interactively with the class as a whole.
Enzymes
Catalysis in BiologyTim Wendorff A section of ChemPrime, the Chemical Educations Digital Library's free General Chemistry textbook.
Catalysis |
Enzymes
ChemPaths 104 M Feb 28John W. Moore Today in Chem 104:
* Lecture: Catalysis
* Reading:
Kotz, Ch. 15, Sec. 6
Moore, Ch. 13, Sec. 8-10
* Homework #6 due by 11:55 pm F Mar 4
* Biomolecules Tutorial: Enzymes (and Enzymes Quiz)
due at 11:55 pm, W Mar 2.
