TIGER

Other Resources: 25 results
Percent Yield  Ed Vitz, John W. Moore
A section of ChemPrime, the Chemical Educations Digital Library's free General Chemistry textbook.
Synthesis
Molecular Models of Products and Reactants from Suzuki and Heck Syntheses  William F. Coleman
Our Featured Molecules this month come from the paper by Evangelos Aktoudianakis, Elton Chan, Amanda R. Edward, Isabel Jarosz, Vicki Lee, Leo Mui, Sonya S. Thatipamala, and Andrew P. Dicks (1), in which they describe the synthesis of 4-phenylphenol using an aqueous-based Suzuki reaction. The authors describe the various ways in which this reaction addresses concerns of green chemistry, and point out that their product bears structural similarity to two non-steroidal anti-inflammatory drugs (NSAIDs), felbinac and diflunisal. A number of molecules from this paper and its online supplemental material have been added to the Featured Molecules collection. Students will first notice that the aromatic rings in the molecules based on a biphenyl backbone are non-planar, as is the case in biphenyl. If they look carefully at diflunisal, they will notice that the carbon atoms are in a different chemical environment. One way in which to see the effect of these differing environments is to examine the effect of atom charge on the energies of the carbon 1s orbitals. Figure 1 shows this effect using charges and energies from an HF/631-G(d) calculation. A reasonable question to ask students would be to assign each of the data points to the appropriate carbon atom. As an extension of this exercise students could produce similar plots using different computational schemes. Are the results the same; are they parallel. This would be a useful problem when dealing with the tricky question of exactly what is meant by atom charge in electronic structure calculations. Students with more expertise in organic chemistry could explore extending the synthesis of 4-phenylphenol to produce more complex bi- and polyphenyl-based drugs. This may well be the first time that they have seen coupling reactions such as the Suzuki and Heck reactions. Students in introductory and non-science-major courses might well find the NSAIDs to be an interesting group of molecules, and could be asked to find information on the variety of molecules that display the anti-inflammatory properties associated with NSAIDs. Do they find structural similarities? Are there various classes of NSAIDs? Are they familiar with any of these molecules? Have they taken any NSAIDs? If so, for what reason? Is there any controversy about any of the NSAIDs? As with all of the molecules in the Featured Molecules collections, those added this month provide us with a number of ways of showing students the practical relevance of what they sometime see only as lines on a page. Molecules do matter.
Synthesis
Creative Chemistry  
Volume 04, issue 15 of a series of leaflets covering subjects of interest to students of elementary chemistry distributed in 1929 - 1932.
Applications of Chemistry |
Synthesis
The Reaction Rolodex; A Web-Based System for Learning Reactions in Organic Chemistry  Eric Mahan
This Web-based system of note cards has been developed to aid students in learning the vast number of reactions encountered in organic chemistry. A thorough knowledge of these reactions is essential for success in first- and second-semester organic chemistry courses. The reactions are organized by functional group and can be chosen from a menu at the left side of the Web page. Once a particular reaction has been selected, the main frame displays the reactant(s) and reagent(s) along with a question mark in place of the product. After considering the reaction as long as needed, the user can click the question mark to reveal the reaction product. Clicking the product will again hide the answer and regenerate the question mark so that the reaction can be practiced again. Selecting other reactions from the menu on the left allows them to be practiced in the same manner.
Reactions
Chemical Reactions (Netorials)  Rachel Bain, Mithra Biekmohamadi, Liana Lamont, Mike Miller, Rebecca Ottosen, John Todd, and David Shaw
Chemical Reactions: this is a resource in the collection "Netorials". The Netorials cover selected topics in first-year chemistry including: Chemical Reactions, Stoichiometry, Thermodynamics, Intermolecular Forces, Acids & Bases, Biomolecules, and Electrochemistry.
Reactions
Spontaneous Processes and Molecular Probability  Ed Vitz, John W. Moore
A section of ChemPrime, the Chemical Educations Digital Library's free General Chemistry textbook.
Reactions
Rates of Spontaneous Processes  Ed Vitz, John W. Moore
A section of ChemPrime, the Chemical Educations Digital Library's free General Chemistry textbook.
Reactions
What Chemists Do  Ed Vitz, John W. Moore
A section of ChemPrime, the Chemical Educations Digital Library's free General Chemistry textbook.
Reactions
Chemical Reactions  American Chemical Society
ACS Science for Kids activities exploring chemical reactions.
Reactions
Molecular Models of Plant Hormones  William F. Coleman
The paper "Synthesis of Plant Auxin Derivatives and Their Effects on Ceratopteris richardii" by Corey E. Stilts and Roxanne Fisher describing an experiment begun in the organic labs and completed in a biochemistry cell biology lab provides the featured molecules for this month. The molecules in Figure 1 of that paper have been added to the collection. There is nothing particularly surprising about their structures, but students might be interested in seeing whether they can determine any structure/regulating effect relationships as the number of synthesized auxin derivatives grows. Additionally, students with little or no biochemistry background might wish to explore other systems that act as growth regulating hormones in plants, as an introduction to the variety of molecular structures that can display such bioactivity. Such molecules range from the very simple, ethene, to the adenine-derived cytokinins (an example of which, zealtin, is shown here) and the brassinosteroids. Brassinolide, a commonly occurring brassin, is also shown. These latter two structures have also been added to the molecule collection. All of the structures have been optimized at the HF/6-31G(d) level.
Synthesis |
Biological Cells |
Hormones |
Bioorganic Chemistry
Energy and the Formation of Ions  Ed Vitz, John W. Moore
A section of ChemPrime, the Chemical Educations Digital Library's free General Chemistry textbook.
Reactions |
Thermodynamics
Le Chatelier's Principle  Ed Vitz, John W. Moore
A section of ChemPrime, the Chemical Educations Digital Library's free General Chemistry textbook.
Reactions |
Equilibrium
The Effect of a Change in Pressure  Ed Vitz, John W. Moore
A section of ChemPrime, the Chemical Educations Digital Library's free General Chemistry textbook.
Reactions |
Equilibrium
Alcohols  Ed Vitz, John W. Moore
A section of ChemPrime, the Chemical Educations Digital Library's free General Chemistry textbook.
Alcohols |
Addition Reactions
Named Reactions  Michael B. Smith
This Web site lists 95 of the most important named reactions in organic chemistry. Each is linked to a Web page that gives the primary reference and equations for one or more recent literature examples that illustrate the use of the reaction.
Nomenclature / Units / Symbols |
Reactions
Named Reagents  Hans J. Reich
This convenient list provides structures of more than 160 common reagents used in organic chemistry that are often referred to by the originator's name, by an acronym, or by a trade name.
Nomenclature / Units / Symbols |
Reactions
Bond Enthalpies and Exothermic or Endothermic Reactions  Ed Vitz, John W. Moore
A section of ChemPrime, the Chemical Educations Digital Library's free General Chemistry textbook.
Calorimetry / Thermochemistry |
Reactions
The Effect of Temperature  Ed Vitz, John W. Moore
A section of ChemPrime, the Chemical Educations Digital Library's free General Chemistry textbook.
Reactions |
Kinetic-Molecular Theory
Macroscopic and Microscopic Views of a Chemical Reaction  Ed Vitz, John W. Moore
A section of ChemPrime, the Chemical Educations Digital Library's free General Chemistry textbook.
Reactions |
Molecular Properties / Structure
Building  American Chemical Society
ACS Science for Kids activities exploring the chemistry behind building many everyday objects and structures.
Industrial Chemistry |
Physical Properties |
Reactions |
Consumer Chemistry
Chemical & Physical Change  American Chemical Society
Everything you see and touch has the ability to change. Sometimes substances change to form new substances. This is called a chemical change. Other times substances change but keep the same identity. This is called a physical change. Try these activities to learn more about chemical and physical change.
Acids / Bases |
Reactions |
Water / Water Chemistry |
Solutions / Solvents |
Consumer Chemistry
Graphing  American Chemical Society
ACS Science for Kids activities explore the aspects of recording scientific data and presenting that data in useful graphs.
Reactions |
Chemometrics |
Physical Properties |
Transport Properties |
Plant Chemistry
Toys-ACS Science for Kids  American Chemical Society
ACS Science for Kids activities explore how chemistry can be used to make toys.
Gases |
Polymerization |
Water / Water Chemistry |
Physical Properties |
Lipids |
Reactions
Air-Solids, Liquids & Gases  American Chemical Society
ACS Science for Kids activities explore the properties of gases.
Atmospheric Chemistry |
Acids / Bases |
Reactions |
Applications of Chemistry |
Water / Water Chemistry |
Gases
Characteristics of Materials  American Chemical Society
What makes diapers absorbent? Is peanut butter stickier than syrup or jelly? Strong, stretchy, sticky, or sweet—everything around us has special properties which make them unique. See if you can identify and compare the characteristics of materials.
Industrial Chemistry |
Physical Properties |
Reactions |
Consumer Chemistry |
Gases |
Carbohydrates |
Proteins / Peptides |
Crystals / Crystallography |
Water / Water Chemistry |
Plant Chemistry |
Dyes / Pigments |
Lipids |
Molecular Properties / Structure |
Applications of Chemistry |
Nutrition |
Acids / Bases |
Chromatography |
Magnetic Properties |
Metals |
Polymerization |
Solutions / Solvents |
Descriptive Chemistry |
Food Science