| Journal Articles: 193 results |
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Assessing Nitration Products of Benzene Derivatives Using TLC Analysis Rita K. Hessley
Thin layer chromatography is applied to an earlier published, guided discovery experiment using GCMS analyses to identify isomers formed by the nitration of mono-substituted benzenes.
Hessley, Rita K. J. Chem. Educ. 2008, 85, 1623.
Thin Layer Chromatography |
Gas Chromatography |
Mass Spectrometry |
Aromatic Compounds
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Identification of Secondary Metabolites in Citrus Fruit Using Gas Chromatography and Mass Spectroscopy Jean-Michel Lavoie, Esteban Chornet, and André Pelletier
Using a simple extraction and a gas chromatograph coupled with a mass spectrometer, this protocol allows students in analytical or organic chemistry to quantify and qualify monoterpenes from the peels of limes, grapefruits, and oranges.
Lavoie, Jean-Michel; Chornet, Esteban; Pelletier, André. J. Chem. Educ. 2008, 85, 1555.
Alkenes |
Food Science |
Gas Chromatography |
Mass Spectrometry |
Natural Products |
Plant Chemistry |
Qualitative Analysis |
Quantitative Analysis
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Borohydride Reduction of Estrone Animesh Aditya, David E. Nichols, and G. Marc Loudon
This experiment presents a guided-inquiry approach to the demonstration of diastereoselectivity using chiral hindered ketones that undergo facile reduction with sodium borohydride. The resulting diastereomeric estradiols can be analyzed and differentiated by thin-layer chromatography and melting point.
Aditya, Animesh; Nichols, David E.; Loudon, G. Marc. J. Chem. Educ. 2008, 85, 1535.
Aldehydes / Ketones |
Diastereomers |
IR Spectroscopy |
Microscale Lab |
Stereochemistry |
Steroids |
Thin Layer Chromatography
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Evaluating Mechanisms of Dihydroxylation by Thin-Layer Chromatography Benjamin T. Burlingham and Joseph C. Rettig
Presents a microscale experiment in which cyclohexene is dihydroxylated under three sets of conditions and the products determined through thin-layer chromatography. Teams of students evaluate proposed mechanisms for each dihydroxylation in light of the data collected.
Burlingham, Benjamin T.; Rettig, Joseph C. J. Chem. Educ. 2008, 85, 959.
Addition Reactions |
Alkenes |
Diastereomers |
Mechanisms of Reactions |
Microscale Lab |
Stereochemistry |
Synthesis |
Thin Layer Chromatography
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Separation of the Carotenoid Bixin from Annatto Seeds Using Thin-Layer and Column Chromatography James V. McCullagh and Nicholas Ramos
In this experiment the carotenoid bixin is isolated from annatto seeds using column chromatography and then analyzed by UVvis and IR spectroscopy. The procedure has several advantages over previous pigment separation experiments.
McCullagh, James V.; Ramos, Nicholas. J. Chem. Educ. 2008, 85, 948.
Chromatography |
Dyes / Pigments |
Natural Products |
Separation Science |
Thin Layer Chromatography |
UV-Vis Spectroscopy
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The Preparation and Enzymatic Hydrolysis of a Library of Esters Elizabeth M. Sanford and Traci L. Smith
In this investigative case study, students work collaboratively to prepare and characterize a library of esters using Fischer esterification and alcoholysis of acid chlorides and their subsequent enzymatic hydrolysis by pig liver and orange peel esterases.
Sanford, Elizabeth M.; Smith, Traci L. J. Chem. Educ. 2008, 85, 944.
Drugs / Pharmaceuticals |
Enzymes |
Esters |
Industrial Chemistry |
IR Spectroscopy |
NMR Spectroscopy |
Synthesis |
Thin Layer Chromatography
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Converting Municipal Waste into Automobile Fuel: Ethanol from Newspaper Mark Mascal and Richard Scown
In this experiment, waste newspaper is pulped with acid and its cellulose hydrolyzed to produce glucose syrup that is fermented and distilled to yield ethanol. In doing so, students are introduced to carbohydrate chemistry and the use of fermentation in organic synthesis.
Mascal, Mark; Scown, Richard. J. Chem. Educ. 2008, 85, 546.
Acids / Bases |
Alcohols |
Applications of Chemistry |
Biotechnology |
Carbohydrates |
Qualitative Analysis |
Synthesis |
Thin Layer Chromatography
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Colorful Column Chromatography: A Classroom Demonstration of a Three-Component Separation Lars V. Heumann
Describes a classroom demonstration for the separation of a ternary mixture consisting of intensely colored compounds using silica gel column chromatography.
Heumann, Lars V. J. Chem. Educ. 2008, 85, 524.
Chromatography |
Separation Science |
Thin Layer Chromatography
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Acylation of Ferrocene: A Greener Approach Kurt R. Birdwhistell, Andy Nguyen, Eric J. Ramos, and Robert Kobelja
This article describes an acylation of ferrocene that is more eco-friendly than the conventional experiment, which has been modified by replacing mineral acid with a polymeric acid catalyst and using microwave instead of conventional heating.
Birdwhistell, Kurt R.; Nguyen, Andy; Ramos, Eric J.; Kobelja, Robert. J. Chem. Educ. 2008, 85, 261.
Catalysis |
Chromatography |
Green Chemistry |
Organometallics |
Synthesis |
Transition Elements |
Brønsted-Lowry Acids / Bases
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Catalytic Hydrogenation of Maleic Acid at Moderate Pressures Kwesi Amoa
This article demonstrates the reduction of maleic acid in about 90 minutes using moderate-pressure catalytic hydrogenation.
Amoa, Kwesi. J. Chem. Educ. 2007, 84, 1948.
Alkenes |
Catalysis |
Chromatography |
IR Spectroscopy |
Laboratory Equipment / Apparatus |
Spectroscopy |
Thin Layer Chromatography
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Determination of the Rotational Barrier for Kinetically Stable Conformational Isomers via NMR and 2D TLC Gregory T. Rushton, William G. Burns, Judi M. Lavin, Yong S. Chong, Perry Pellechia, and Ken D. Shimizu
After the synthesis of a N,N'-diaryl naphthalene diimide, students estimate the rotational barrier about a CarylNimidesingle bond by studying the reequilibration of the two resulting isomers using two-dimensional thin-layer chromatography, followed by a more accurate determination through a 1H NMR time study.
Rushton, Gregory T.; Burns, William G.; Lavin, Judi M.; Chong, Yong S.; Pellechia, Perry; Shimizu, Ken D. J. Chem. Educ. 2007, 84, 1499.
Alcohols |
Chromatography |
Conformational Analysis |
Equilibrium |
Kinetics |
NMR Spectroscopy |
Physical Properties |
Rate Law |
Thin Layer Chromatography
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Synthesis of Anomeric Methyl Fructofuranosides and Their Separation on an Ion-exchange Resin Erkki Nurminen, Päivi Poijärvi, Katja Koskua, and Jari Hovinen
Treatment of d-fructose with methanol in the presence of acid as a catalyst gives a mixture of methyl--d-fructopyranoside, methyl-a-D-fructofuranoside, and methyl--d- fructofuranoside, which are separated on an ion exchange column and characterized polarimetrically.
Nurminen, Erkki; Poijärvi, Päivi; Koskua, Katja; Hovinen, Jari. J. Chem. Educ. 2007, 84, 1480.
Carbocations |
Chirality / Optical Activity |
Chromatography |
Ion Exchange |
NMR Spectroscopy |
Synthesis |
Thin Layer Chromatography |
Carbohydrates
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Analysis and Identification of Acid–Base Indicator Dyes by Thin-Layer Chromatography Daniel D. Clark
Presents an experiment that serves to illustrate the fundamentals and utility of thin-layer chromatography through the resolution and identification of brightly colored, acidbase indicator dyes on the basis of Rf values and color.
Clark, Daniel D. J. Chem. Educ. 2007, 84, 1186.
Acids / Bases |
Dyes / Pigments |
Thin Layer Chromatography
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Digitally Enhanced Thin-Layer Chromatography: An Inexpensive, New Technique for Qualitative and Quantitative Analysis Amber Victoria Irish Hess
Thin-layer chromatography enhanced by digital photography is ideal for high school and college labs and can perform qualitative and quantitative analysis comparable to more expensive, high-performance TLC equipment. Using common photo-editing software, one can quickly produce multi-spectral scans, densitograms, and calibration curves, output previously limited to HPTLC.
Hess, Amber Victoria Irish. J. Chem. Educ. 2007, 84, 842.
Laboratory Equipment / Apparatus |
Qualitative Analysis |
Quantitative Analysis |
Thin Layer Chromatography |
Instrumental Methods |
Chromatography
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Isolation of Three Components from Spearmint Oil: An Exercise in Column and Thin-Layer Chromatography Don R. Davies and Todd M. Johnson
In this exercise, the three major components of spearmint oil, (+)-limonene, L-(-)-carvone, and (1R,2R,4R)-dihydrocarveol, are separated by silica gel column chromatography. The separation is monitored by thin-layer chromatography, and IR analysis is employed to verify the identity of the separated components.
Davies, Don R.; Johnson, Todd M. J. Chem. Educ. 2007, 84, 318.
Chirality / Optical Activity |
Chromatography |
Natural Products |
Microscale Lab |
Thin Layer Chromatography |
Separation Science
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Creatine Synthesis: An Undergraduate Organic Chemistry Laboratory Experiment Andri L. Smith and Paula Tan
Describes the synthesis of creatine monohydratea popular supplement used in sports requiring short bursts of energyfor introductory organic chemistry laboratory courses. The synthesis illustrates the electrophilic nature of nitriles, as well as the nucleophilic nature of amines.
Smith, Andri L.; Tan, Paula. J. Chem. Educ. 2006, 83, 1654.
Amines / Ammonium Compounds |
Aqueous Solution Chemistry |
Bioorganic Chemistry |
Chromatography |
Dyes / Pigments |
Mechanisms of Reactions |
Microscale Lab |
Thin Layer Chromatography
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Calix[4]pyrrole: Synthesis and Anion-Binding Properties. An Organic Chemistry Laboratory Experiment James A. Shriver and Scott G. Westphal
Simple calixpyrrole macrocycles provide an easy-to-synthesize example of an anion-binding agent that can be included in the undergraduate laboratory curriculum. The inclusion of a test for anion binding also makes this procedure suitable for a more advanced audience and supplies a bridge for the introduction of supramolecular chemistry and a typical hostguest interaction.
Shriver, James A.; Westphal, Scott G. J. Chem. Educ. 2006, 83, 1330.
Aromatic Compounds |
Hydrogen Bonding |
Molecular Recognition |
Synthesis |
Thin Layer Chromatography
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Purification and Modification of Fullerene C60 in the Undergraduate Laboratory Tracey Spencer, Barney Yoo, and Kent Kirshenbaum
Describes an experiment for the extraction and column purification of buckminsterfullerene from fullerene-rich soot followed by a one-pot 1,3-dipolar cycloaddition of an azomethine ylide. Characterization of the starting material and product can be performed by UVVis, MS, 1H NMR, and 13C NMR.
Spencer, Tracey; Yoo, Barney; Kirshenbaum, Kent. J. Chem. Educ. 2006, 83, 1218.
Aromatic Compounds |
Chromatography |
NMR Spectroscopy |
UV-Vis Spectroscopy |
Synthesis |
Nanotechnology |
Reactions
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Regiospecific Epoxidation of Carvone: A Discovery-Oriented Experiment for Understanding the Selectivity and Mechanism of Epoxidation Reactions Kendrew K. W. Mak, Y. M. Lai, and Yuk-Hong Siu
Peroxy acids and alkaline H2O2 are two commonly used reagents for alkene epoxidation. The former react preferentially with electron-rich alkenes while the latter works better with a,-unsaturated carbonyl compounds. The selectivity of these two reagents on carvone, a naturally occurring compound that contains both types of C=C bonds, is investigated.
Mak, Kendrew K. W.; Lai, Y. M.; Siu, Yuk-Hong. J. Chem. Educ. 2006, 83, 1058.
Alkenes |
Chromatography |
Epoxides |
IR Spectroscopy |
NMR Spectroscopy |
Synthesis |
Mechanisms of Reactions
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A Greener Approach to Aspirin Synthesis Using Microwave Irradiation Ingrid Montes, David Sanabria, Marilyn García,, Joaudimir Castro, and Johanna Fajardo
Presents an inquiry-based laboratory experience based on the use of a microwave oven as a means for a comparative study of the effect of different catalysts in the synthesis of aspirin.
Montes, Ingrid; Sanabria, David; García,, Marilyn; Castro, Joaudimir; Fajardo, Johanna. J. Chem. Educ. 2006, 83, 628.
Drugs / Pharmaceuticals |
Esters |
Green Chemistry |
NMR Spectroscopy |
Reactions |
Synthesis |
Thin Layer Chromatography
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Environmentally Responsible Redox Chemistry: An Example of Convenient Oxidation Methodology without Chromium Waste Robyn L. Crumbie
This article describes a simple experiment that uses recyclable Magtrieve as the oxidant in a simple reaction sequence emphasizing the reciprocity of oxidation and reduction processes in organic synthesis.
Crumbie, Robyn L. J. Chem. Educ. 2006, 83, 268.
Chromatography |
Green Chemistry |
IR Spectroscopy |
Oxidation / Reduction |
Synthesis
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Derivatization of Fullerenes: An Organic Chemistry Laboratory Charles T. Cox Jr. and Melanie M. Cooper
Presents two undergraduate organic chemistry laboratories detailing the synthesis of fullerene derivatives, using the Bingel (carbene insertion) and Prato (1,3-dipolar addition) protocols.
Cox, Charles T., Jr.; Cooper, Melanie M. J. Chem. Educ. 2006, 83, 99.
Acids / Bases |
Addition Reactions |
Chromatography |
Heterocycles |
IR Spectroscopy |
Microscale Lab |
NMR Spectroscopy |
Synthesis |
UV-Vis Spectroscopy
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The Virtual ChemLab Project: A Realistic and Sophisticated Simulation of Organic Synthesis and Organic Qualitative Analysis Brian F. Woodfield, Merritt B. Andrus, Gregory L. Waddoups, Melissa S. Moore, Richard Swan, Rob Allen, Greg Bodily, Tricia Andersen, Jordan Miller, Bryon Simmons, and Richard Stanger
Describes a set of sophisticated and realistic laboratory simulations for use in freshman- and sophomore-level chemistry classes and laboratories called Virtual ChemLab. The purpose of these simulations is to reinforce concepts taught in the classroom, provide an environment for creative learning, and emphasize the thinking behind instructional laboratory experiments.
Woodfield, Brian F.; Andrus, Merritt B.; Waddoups, Gregory L.; Moore, Melissa S.; Swan, Richard; Allen, Rob; Bodily, Greg; Andersen, Tricia; Miller, Jordan; Simmons, Bryon; Stanger, Richard. J. Chem. Educ. 2005, 82, 1728.
IR Spectroscopy |
NMR Spectroscopy |
Qualitative Analysis |
Synthesis |
Reactions |
Thin Layer Chromatography
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The Discovery-Oriented Approach to Organic Chemistry. 6. Selective Reduction in Organic Chemistry: Reduction of Aldehydes in the Presence of Esters Using Sodium Borohydride Ashvin R. Baru and Ram S. Mohan
Describes two discovery oriented lab experiments involving the chemoselective reduction of vanillin acetate and methyl 4-formylbenzoate in the presence of esters using sodium borohydride, followed by product identification using 1H and 13C NMR spectroscopy.
Baru, Ashvin R.; Mohan, Ram S. J. Chem. Educ. 2005, 82, 1674.
NMR Spectroscopy |
Alcohols |
Aldehydes / Ketones |
Esters |
Oxidation / Reduction |
Thin Layer Chromatography |
Synthesis
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An Engaging Illustration of the Physical Differences among Menthol Stereoisomers Edward M. Treadwell and T. Howard Black
The differences and similarities in the physical behavior of enantiomers and diastereomers can easily be demonstrated using the commercial stereoisomers (-)-menthol, (+)-menthol, (+)-isomenthol, and (+)-neomenthol. Thin-layer chromatography and melting point determinations clearly show that diastereomers have different physical properties from enantiomers and each other, but that enantiomers have identical physical properties in achiral environments. By obtaining a mixed melting point and optical rotations the difference in enantiomers can be observed.
Treadwell, Edward M.; Black, T. Howard. J. Chem. Educ. 2005, 82, 1046.
Chirality / Optical Activity |
Stereochemistry |
Thin Layer Chromatography |
Diastereomers |
Enantiomers |
Physical Properties
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Checkerboard Chromatography Charles A. Smith
This hands-on activity allows students to simulate chromatographic simulations using a grid, colored pieces of paper, and a six-sided die. Students observe the separation as it is occurring and perform experiments on flow rate, column length, and mobile phase composition.
Smith, Charles A. J. Chem. Educ. 2004, 81, 384A.
Chromatography |
Instrumental Methods |
Separation Science
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Students' Attitudes toward and Conceptual Understanding of Chemical Instrumentation Larry S. Miller, Mary B. Nakhleh, John J. Nash, and Jeanne A. Meyer
Data collected from field notes, surveys, and interviews are used to evaluate (i) the attitudes students have toward using instrumentation, (ii) how students relate the underlying chemical concepts to the instrumentation, and (iii) how working in a group impacts students' attitudes toward, and their conceptual understanding of, chemical instrumentation.
Miller, Larry S.; Nakhleh, Mary B.; Nash, John J.; Meyer, Jeanne A. J. Chem. Educ. 2004, 81, 1801.
Chromatography |
Instrumental Methods |
IR Spectroscopy |
Laboratory Equipment / Apparatus
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Solvent-Free Wittig Reaction: A Green Organic Chemistry Laboratory Experiment Sam H. Leung and Stephen A. Angel
In this experiment (E)- and (Z)-1-(4-bromophenyl)-2-phenylethene are synthesized by a solvent-free Wittig reaction. The reaction is effected by grinding the reactants in a mortar with a pestle. Both the E and Z isomers of the product are produced as evidenced by thin-layer chromatography and 1H NMR analysis. The E isomer is isolated by crystallization with ethanol in this experiment. In addition to learning about the Wittig reaction, students are also introduced to the ideas of mechanochemistry and green chemistry.
Leung, Sam H.; Angel, Stephen A. J. Chem. Educ. 2004, 81, 1492.
Chromatography |
Green Chemistry |
Microscale Lab |
NMR Spectroscopy |
Synthesis |
Reactions |
Aldehydes / Ketones |
Alkenes
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Benzoin Condensation: Monitoring a Chemical Reaction by High-Pressure Liquid Chromatography Apurba Bhattacharya, Vikram C. Purohit, and Nicholas R. Beller
High-pressure liquid chromatography was successfully introduced in the undergraduate advanced organic chemistry laboratory to reinvestigate the cyanide-catalyzed condensation of benzaldehyde to benzoin.
Bhattacharya, Apurba; Purohit, Vikram C.; Beller, Nicholas R. J. Chem. Educ. 2004, 81, 1020.
HPLC |
Chromatography |
Quantitative Analysis |
Synthesis |
Instrumental Methods
|
Developing Investigation Skills in an Introductory Multistep Synthesis Using Fluorene Oxidation and Reduction Mark G. Stocksdale, Steven E. S. Fletcher, Ian Henry, Paul J. Ogren, Michael A. G. Berg, Roy D. Pointer, and Barrett W. Benson
A two-step reaction sequence in the beginning organic laboratory provides a useful introduction to the importance of multistep synthesis. In addition to introducing several common synthetic methods and techniques, a two-step preparation can quickly establish the importance of testing alternative reactions in order to optimize intermediate yields.
Stocksdale, Mark G.; Fletcher, Steven E. S.; Henry, Ian; Ogren, Paul J.; Berg, Michael A. G.; Pointer, Roy D.; Benson, Barrett W. J. Chem. Educ. 2004, 81, 388.
Chromatography |
IR Spectroscopy |
NMR Spectroscopy |
Synthesis |
Aromatic Compounds |
Oxidation / Reduction
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An Improved Method for the Extraction and Thin-Layer Chromatography of Chlorophyll a and b from Spinach Hao T. Quach, Robert L. Steeper, and G. William Griffin
A direct method of extracting plant pigments from spinach leaves into a dry organic solvent is presented. This method avoids liquidliquid extractions and subsequent drying as is found in previously reported methods.
Quach, Hao T.; Steeper, Robert L.; Griffin, G. William. J. Chem. Educ. 2004, 81, 385.
Chromatography |
Natural Products |
Plant Chemistry |
Separation Science |
Thin Layer Chromatography
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The Separation and Identification of Two Unknown Solid Organic Compounds: An Experiment for the Sophomore Organic Chemistry Laboratory Patty L. Feist
Students are given a mixture of a solid ketone and a solid alcohol and asked to separate and identify the two components. First the students use TLC to determine the optimum solvent system to separate the two compounds, then they separate the unknowns on a microscale flash chromatography column. The students acquire the melting point, and if possible, the IR and 1H NMR spectra for each separated compound and identify them by matching the observed data with that of known compounds.
Feist, Patty L. J. Chem. Educ. 2004, 81, 109.
Chromatography |
IR Spectroscopy |
Microscale Lab |
NMR Spectroscopy |
Separation Science |
Qualitative Analysis
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The Base-Induced Reaction of Salicylaldehyde with 1-Bromobutane in Acetone: Two Related Examples of Chemical Problem Solving Holly D. Bendorf and Chriss E. McDonald
Each student performs his or her own experimental work, running one of the two reactions, and acquiring the proton and carbon NMR, IR, and mass spectra. The students work in groups to propose structures for the products and mechanisms for their formation. The students are also asked to address why the reactions take different courses.
Bendorf, Holly D.; McDonald, Chriss E. J. Chem. Educ. 2003, 80, 1185.
Chromatography |
Mass Spectrometry |
NMR Spectroscopy |
Aromatic Compounds |
Aldehydes / Ketones |
Ethers |
Phenols |
IR Spectroscopy
|
Chemical Applications of a Programmable Image Acquisition System Paul J. Ogren, Ian Henry, Steven E. S. Fletcher, and Ian Kelly
A programmable imaging system for thin-layer and kinetics measurements; examples of applications include well plate analysis, TLC quantitative analysis of acetaminophen and aspirin, analysis of electrophoresis bands, and kinetics of toluidine blue reduction by sulfite.
Ogren, Paul J.; Henry, Ian; Fletcher, Steven E. S.; Kelly, Ian. J. Chem. Educ. 2003, 80, 699.
Instrumental Methods |
Laboratory Computing / Interfacing |
Laboratory Equipment / Apparatus |
Chromatography |
Kinetics |
Quantitative Analysis |
Electrophoresis
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Integrating HPLC and Electrochemistry: A LabVIEW-Based Pulsed Amperometric Detection System Mark B. Jensen
Using the voltametry of glucose to develop a method for the pulsed amperometric detection of carbohydrates (glucose, fructose, and sucrose) following their separation by liquid chromatography.
Jensen, Mark B. J. Chem. Educ. 2002, 79, 345.
Chromatography |
Electrochemistry |
Instrumental Methods |
HPLC |
Carbohydrates |
Separation Science |
Oxidation / Reduction
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A Preparative TLC Applicator Tom Lyons Fisher and Charles P. Gilman
The construction of a simple and inexpensive sample applicator for preparative thin layer chromatography is described.
Fisher, Tom Lyons; Gilman, Charles P. J. Chem. Educ. 2001, 78, 367.
Laboratory Equipment / Apparatus |
Chromatography |
Separation Science |
Thin Layer Chromatography
|
What Factors Affect the Separation of Substances Using Thin-Layer Chromatography? An Undergraduate Experiment John J. Nash, Jeanne A. Meyer, and Barbara Everson
The experiment reported here illustrates the potentially dramatic effects on TLC Rf values of not equilibrating the solvent atmosphere during development of a TLC plate.
Nash, John J.; Meyer, Jeanne A.; Everson, Barbara. J. Chem. Educ. 2001, 78, 364.
Chromatography |
Thin Layer Chromatography
|
Rapid, Simple Quantitation in Thin-Layer Chromatography Using a Flatbed Scanner Mitchell E. Johnson
Simply scanning a visibly stained TLC plate into a computer substitutes for much more expensive plate readers. With common image analysis software, "elution" profiles can be obtained. The resulting "chromatograms" can be analyzed in the same manner as other chromatograms.
Johnson, Mitchell E. J. Chem. Educ. 2000, 77, 368.
Chromatography |
Instrumental Methods |
Laboratory Equipment / Apparatus |
Quantitative Analysis |
Thin Layer Chromatography
|
Identification of Pharmaceuticals via Computer-Aided Thin Layer Chromatography Anthony J. Macherone Jr. and Theodore J. Siek
This analytical laboratory experiment demonstrates the methodology of TLC in its relation to toxicology and forensic chemistry. It is easily adapted for high school seniors or undergraduates and employs experimental techniques associated with TLC and post-lab data analysis with concomitant introduction of concepts.
Macherone, Anthony J., Jr.; Siek, Theodore J. J. Chem. Educ. 2000, 77, 366.
Forensic Chemistry |
Drugs / Pharmaceuticals |
Toxicology |
Thin Layer Chromatography |
Separation Science
|
Isolating trans-Anethole from Anise Seeds and Elucidating Its Structure: A Project Utilizing One- and Two-Dimensional NMR Spectrometry Joseph W. LeFevre
This three-week project involves isolating and purifying a natural product and determining its structure. trans-Anethole is isolated from anise seeds by steam distillation and liquid-liquid extraction. The crude product is analyzed by thin-layer chromatography and purified by flash chromatography.
LeFevre, Joseph W. . J. Chem. Educ. 2000, 77, 361.
Chromatography |
IR Spectroscopy |
Natural Products |
NMR Spectroscopy |
Separation Science |
Molecular Properties / Structure |
Thin Layer Chromatography
|
Isolation of Curcumin from Turmeric Andrew M. Anderson, Matthew S. Mitchell, and Ram S. Mohan
The active ingredient in turmeric is curcumin, which is approximately 2% by weight of the root of turmeric. We have developed two simple procedures for isolation of curcumin from turmeric, making this a new and interesting natural product isolation experiment.
Anderson, Andrew M.; Mitchell, Matthew S.; Mohan, Ram S. J. Chem. Educ. 2000, 77, 359.
Chromatography |
Medicinal Chemistry |
Natural Products |
Synthesis |
Separation Science |
Aromatic Compounds
|
Computational Investigations for Undergraduate Organic Chemistry: Modeling a TLC Exercise to Investigate Molecular Structure and Intermolecular Forces Rita K. Hessley
In this exercise students carry out a pre-lab exercise in which they compute the dipole moment for a set of similar models representing a variety of functional group categories. Using their data, and supported by guided class discussion, students propose a working hypothesis about how TLC can be used to demonstrate the manner in which the relevant forces lead to predictable rates (extent, Rf) of elution.
Hessley, Rita K. J. Chem. Educ. 2000, 77, 203.
Computational Chemistry |
Noncovalent Interactions |
Thin Layer Chromatography
|
Separation of Polyaromatic Hydrocarbons Using 2-Dimensional Thin-Layer Chromatography. An Environmental Chemistry Experiment Geoffrey T. Crisp and Natalie M. Williamson
Students are given a soil sample from which they extract two (previously added) polyaromatic hydrocarbons (PAHs) using a Soxhlet apparatus. They determine the identity of the unknown PAHs by comparing the 2-dimensional thin-layer chromatograms of the soil sample extract and a standard solution, both of which they must run themselves.
Crisp, Geoffrey T.; Williamson, Natalie M. J. Chem. Educ. 1999, 76, 1691.
Aromatic Compounds |
Chromatography |
Thin Layer Chromatography |
Separation Science
|
Student Understanding of Chromatography: A Hands-On Approach Robert D. Curtright, Randy Emry, and John Markwell*
This exercise sets up a collaborative activity that challenges students to develop a chromatographic solvent with the appropriate polarity to separate leaf chlorophyll and anthocyanin pigments by TLC. The suggested activity has been tested with both high-school advanced-chemistry students and with undergraduate students in an introductory biochemistry class.
Curtright, Robert D.; Emry, Randy; Markwell, John. J. Chem. Educ. 1999, 76, 249.
Chromatography |
Natural Products |
Separation Science |
Undergraduate Research |
Thin Layer Chromatography
|
The Preparation of a Fluorescent Dye: A Microscale TLC Experiment Daniel S. Calimente, Shannon M. Strand, Shao-Chieh Chang, and David E. Lewis
This paper describes an experiment that allows the instructor to introduce TLC as a technique for analyzing reaction mixtures by monitoring the formation of a fluorescent dye. The experiment also illustrates the effects of eluting solvent on elution order.
Calimente, Daniel S.; Strand, Shannon M.; Chang, Shao-Chieh; Lewis, David E. J. Chem. Educ. 1999, 76, 82.
Chromatography |
Dyes / Pigments |
Photochemistry |
Microscale Lab |
Thin Layer Chromatography
|
Chemical Analysis of an Endangered Conifer: Environmental Laboratory Experiments Royce S. Woosley and David J. Butcher
Elemental analysis of foliage was used to assess the effects of acidic deposition and pollution levels. Volatile compounds were identified and determined in foliage and other plant tissues by gas chromatography-mass spectrometry (GC-MS) and GC. Chlorophylls a and b were determined by ultraviolet-visible spectroscopy by simultaneous analysis of a two-component mixture.
Woosley, Royce S.; Butcher, David J. J. Chem. Educ. 1998, 75, 1592.
Plant Chemistry |
Quantitative Analysis |
Gas Chromatography |
Mass Spectrometry
|
A Simplified Method for the Microscale Extraction of Pigments from Spinach Kimberley R. Cousins and Kathleen M. Pierson
A method is presented for microscale sample preparation for the thin-layer chromatographic analysis of the pigments in spinach. A commercial vegetable juicer is used for the initial extraction from spinach. This is followed by filtration, liquid/liquid extraction, centrifugation, and evaporation.
Cousins, Kimberley R.; Pierson, Kathleen M. J. Chem. Educ. 1998, 75, 1268.
Chromatography |
Microscale Lab |
Plant Chemistry |
Dyes / Pigments |
Thin Layer Chromatography |
Separation Science
|
A Simple Streaking Device For Preparative Thin Layer Chromatography Yong J. Kim
If the right tool is not available, loading a sample on a TLC plate is fairly tedious and time consuming. This article describes a procedure for making a simple and convenient streaking device from a Pasteur pipet.
Kim, Yong, J. J. Chem. Educ. 1998, 75, 640.
Thin Layer Chromatography |
Laboratory Management
|
HPLC for Undergraduate Introductory Laboratories Scott A. Van Arman and Marcus W. Thomsen
A set of simple HPLC separations as part of an introductory set of projects that serve as an introduction to chromatography early in the organic course; quantitative analysis has been introduced to the common separation of analgesics so that students may identify the composition of an unknown commercial tablet.
Van Arman, Scott A. and Thomsen, Marcus W. J. Chem. Educ. 1997, 74, 49.
Chromatography |
Quantitative Analysis |
HPLC |
Separation Science
|
Modern Practice of Liquid Chromatography: Before and after 1971 Lloyd R. Snyder
A selective history (1941 through 1990) is reported of the development of high performance liquid chromatography (HPLC) from the perspective of the author. Emphasis is given to how a practical understanding of the technique emerged.
Snyder, Lloyd, R. J. Chem. Educ. 1997, 74, 37.
Chromatography |
HPLC |
Separation Science
|
Containment of Spray Reagents in TLC Spot Detection Josef G. Krause
If spraying a reagent with a power pac type device is preferred for this or some other reason, we suggest spraying the reagent inside of a twist tie-sealed, clear-plastic kitchen garbage bag.
Krause, Josef G. J. Chem. Educ. 1996, 73, 979.
Separation Science |
Thin Layer Chromatography |
Chromatography |
Laboratory Management
|
Thin-Layer Chromatography Experiments That Illustrate General Problems in Chromatography M. Lederer, E. Leipzig-Pagani
A number of chromatography experiments using cellulose thin layers and aqueous eluents are proposed to illustrate how chromatography can be used for "pattern recognition" of the inks of felt-tip pens, the principle of displacement chromatography of the constituents of the antiseptic Mercurochrome, salting-out chromatography for the separation of halides, and the impossibility to use chromatography alone as a method of identification.
Lederer, M.; Leipzig-Pagani, E. J. Chem. Educ. 1996, 73, 974.
Chromatography |
Dyes / Pigments |
Thin Layer Chromatography |
Separation Science
|
Organic Qualitative Analysis at the Microscale Level Craig, Rhoda E. R.; Kaufman, Kurt K.
Project requiring students to identify pure unknowns and the components of mixtures using a variety of chromatography and spectrometry techniques.
Craig, Rhoda E. R.; Kaufman, Kurt K. J. Chem. Educ. 1995, 72, A102.
NMR Spectroscopy |
IR Spectroscopy |
Chromatography |
Separation Science |
Qualitative Analysis |
Acids / Bases
|
Phosphatidylcholine from "Healthful" Egg Yolk Varieties: An Organic Laboratory Experience Linda C. Hodges
Using chromatography to isolate and analyze phosphatidylcholine from chickens raised on different diets.
Hodges, Linda C. J. Chem. Educ. 1995, 72, 1140.
Chromatography |
Separation Science |
Lipids
|
An Undergraduate Thin-Layer Chromatography Experiment: Olfactory Delights Mary Anne Lynch, Wendy Gloffke, and Richard A. Rauner
Procedure for separating flavors and fragrances using thin-layer chromatography.
Lynch, Mary Anne; Gloffke, Wendy; Rauner, Richard A. J. Chem. Educ. 1995, 72, 1137.
Chromatography |
Separation Science |
Food Science |
Thin Layer Chromatography
|
More Plates in One Chromatographic Tank Jamil Anwar
Suggested modifications to chromatographic tanks to accommodate more plates per tank.
Anwar, Jamil. J. Chem. Educ. 1995, 72, 1136.
Chromatography |
Laboratory Equipment / Apparatus |
Laboratory Management
|
Thin-Layer Chromatography of Analgesics--An Update John W. Elder
Procedure for identifying ibuprofen, naproxen sodium, acetominaphen, aspirin, and caffeine on commercial chromatography sheets containing a fluorescent indicator.
Elder, John W. J. Chem. Educ. 1995, 72, 1049.
Chromatography |
Separation Science |
Drugs / Pharmaceuticals |
Thin Layer Chromatography |
Qualitative Analysis |
Aromatic Compounds
|
A Simple, Discovery-Based Laboratory Exercise: The Molecular Mass Determination of Polystyrene Greg A. Slough
Identification of an unknown polymer using silica gel TLC sheets and IR spectroscopy.
Slough, Greg A. J. Chem. Educ. 1995, 72, 1031.
Stoichiometry |
IR Spectroscopy |
Molecular Properties / Structure |
Thin Layer Chromatography
|
Acetylation of Ferrocene: A Study of the Friedel-Crafts Acylation Mechanism as Measured by HPLC Using an Internal Standard Newirth, Terry L.; Srouji, Nadine
An experimental procedure that allows students to reach conclusions about the mechanism of an organic reaction (Friedel-Crafts acylation) based on their own data analysis; includes sample data and analysis.
Newirth, Terry L.; Srouji, Nadine J. Chem. Educ. 1995, 72, 454.
Mechanisms of Reactions |
Synthesis |
Chromatography |
HPLC
|
Liquid Chromatographic Determination of UV Absorbers in Sunscreens Davis, Mary R.; Quigley, Michael N.
Using liquid chromatography with UV absorbence to determine the concentration of compounds that block UV radiation in commercial sunscreens; includes sample data.
Davis, Mary R.; Quigley, Michael N. J. Chem. Educ. 1995, 72, 279.
Chromatography |
Separation Science |
Consumer Chemistry |
Quantitative Analysis
|
The Identification of Aspirin-Free Bayer Products: An Alternative to the Classical TLC of Analgesics (1) Cawley, John J.
Procedure for identifying several non-aspirin analgesics using using thin layer chromatography and an ultraviolet lamp.
Cawley, John J. J. Chem. Educ. 1995, 72, 272.
Drugs / Pharmaceuticals |
Chromatography |
Separation Science |
Thin Layer Chromatography |
Qualitative Analysis
|
An Enhanced Chromatographic Technique for the Preparative Scale Purification of Acetyl Ferrocene Davis, James; Vaughan, D. Huw; Cardosi Marco F.
Method and apparatus for producing and purifying significant amounts of acetyl ferrocene for laboratory analysis.
Davis, James; Vaughan, D. Huw; Cardosi Marco F. J. Chem. Educ. 1995, 72, 266.
Synthesis |
Laboratory Management |
Chromatography
|
Microscale Column Chromatographic Isolation of a Red Pigment from Paprika West, Kevin J.; Rauch, Paul
Modification of a macroscopic procedure to a microscale experiment.
West, Kevin J.; Rauch, Paul J. Chem. Educ. 1994, 71, A59.
Microscale Lab |
Chromatography |
Separation Science |
Dyes / Pigments
|
The ABC's of Chromatography: A Colorful Demonstration. Reynolds, Robert C.; Comber, Robert N.
This demonstration involves the separation of combinations of seven highly colored dyes by thin layer chromatography to help explain separation science while capturing the attention of the audience by spelling words with these dyes.
Reynolds, Robert C.; Comber, Robert N. J. Chem. Educ. 1994, 71, 1075.
Thin Layer Chromatography |
Dyes / Pigments |
Separation Science
|
A Computational Introduction to Chromatographic Bandshape Analysis Kevra, S. A.; Bergman, D. L.; Maloy, J. T.
This paper describes a numerical method that has been used as an introduction to chromatographic principles.
Kevra, S. A.; Bergman, D. L.; Maloy, J. T. J. Chem. Educ. 1994, 71, 1023.
Chromatography |
Transport Properties
|
Isolation of piperine from black pepper Epstein, William W.; Netz, David F.; Seidel, Jimmy L.
A new and interesting natural product for isolation in the organic chemistry lab. This procedure also introduces students to many important instruments and procedures in organic chemistry.
Epstein, William W.; Netz, David F.; Seidel, Jimmy L. J. Chem. Educ. 1993, 70, 598.
Natural Products |
Chromatography |
Separation Science
|
Liquid chromatographic determination of malic and lactic acids in wine following malolactic fermentation Brogley, John; Mullick, Joydip; Quigley, Michael N.
This lab takes advantage of wine's unique position in society to invite students to participate in an engaging actvity.
Brogley, John; Mullick, Joydip; Quigley, Michael N. J. Chem. Educ. 1993, 70, 507.
Consumer Chemistry |
Food Science |
Acids / Bases |
Chromatography |
Quantitative Analysis |
Alcohols |
Applications of Chemistry
|
The microscale synthesis and the structure determination of endo-9-methoxycarbonyl-3-oxatricyclo[4,2,1,0 4,5]-2-nonanone. Lee, Moses.
The microscale synthesis and the structure determination of endo-9-methoxycarbonyl-3-oxatricyclo[4,2,1,0 4,5]-2-nonanone.
Lee, Moses. J. Chem. Educ. 1992, 69, A172.
Microscale Lab |
Synthesis |
Aldehydes / Ketones |
Fourier Transform Techniques |
NMR Spectroscopy |
IR Spectroscopy |
Gas Chromatography |
Thin Layer Chromatography |
Instrumental Methods
|
Size-exclusion chromatography: Separating large molecules from small McLoughlin, Daniel J.
Description, theory, demonstration, and experimental procedure regarding size-exclusion chromatography.
McLoughlin, Daniel J. J. Chem. Educ. 1992, 69, 993.
Chromatography |
Separation Science
|
Urinary excretion of paracetamol: A thin-layer chromatography exercise for nursing students. Hickman, Raymond J. S.
Using thin-layer chromatography in a laboratory designed to confirm some important features of the usual textbook description of drug metabolism and excretion.
Hickman, Raymond J. S. J. Chem. Educ. 1992, 69, 510.
Thin Layer Chromatography |
Medicinal Chemistry
|
An internal comparison of the intermolecular forces of common organic functional groups: A thin-layer chromatography experiment Beauvais, Robert; Holman, R. W.
Due to the latest trends in organic chemistry textbook content sequences, it has become desirable to develop an experiment that is rapid, simple, and general, that would compare and contrast the various functional group classes of organic molecules in terms of their relative polarities, dipole moments, and intermolecular forces of attraction.
Beauvais, Robert; Holman, R. W. J. Chem. Educ. 1991, 68, 428.
Alkanes / Cycloalkanes |
Alkenes |
Alcohols |
Carboxylic Acids |
Aldehydes / Ketones |
Esters |
Qualitative Analysis |
Thin Layer Chromatography |
Noncovalent Interactions |
Molecular Properties / Structure
|
Column chromatography: Isolation of caffeine Taber, Douglass F.; Hoerrner, R. Scott
An undergraduate laboratory procedure for isolating caffeine via column chromatography.
Taber, Douglass F.; Hoerrner, R. Scott J. Chem. Educ. 1991, 68, 73.
Chromatography |
Separation Science |
Natural Products |
Drugs / Pharmaceuticals |
Food Science
|
Color reactions and thin-layer chromatography of amino acids: An undergraduate organic chemistry experiment for students in the allied health sciences Hurst, Michael O.; Cobb, D. Keith
Students identify unknowns by determining Rf's and applying color reagents to the chromatograms.
Hurst, Michael O.; Cobb, D. Keith J. Chem. Educ. 1990, 67, 978.
Thin Layer Chromatography |
Amino Acids |
Qualitative Analysis
|
Identification of unknowns by melting point and thin-layer chromatography in combination Levine, Samuel G.
Identification from among 12 unknowns by melting point and thin-layer chromatography.
Levine, Samuel G. J. Chem. Educ. 1990, 67, 972.
Physical Properties |
Thin Layer Chromatography |
Qualitative Analysis
|
Amino acid chromatography: The "best" technique for student labs Helser, Terry L.
Comparisons of linear, conical, and circular chromatograms, as well as media and elutants.
Helser, Terry L. J. Chem. Educ. 1990, 67, 964.
Amino Acids |
Chromatography |
Separation Science
|
Determination of components in beverages by thin-layer chromatography: An undergraduate analytical chemistry experiment Ma, Yinfa; Yeung, Edward S.
This is a description of a simple and interesting thin layer chromatography experiment using three different fluorescence detection principles for the determination of caffeine, saccharin, and sodium benzoate in beverages.
Ma, Yinfa; Yeung, Edward S. J. Chem. Educ. 1990, 67, 428.
Thin Layer Chromatography |
Food Science
|
Conical thin-layer chromatography Heinzen, Horacio; Ferreira, Fernando; Vazquez, Alvaro; Moyna, Patrick
The use of common funnels makes it possible to run thin layer chromatography's (TLC's) with tridimensional characteristics using the same stationary phases, solvent systems, and detection methods as in planar TLC.
Heinzen, Horacio; Ferreira, Fernando; Vazquez, Alvaro; Moyna, Patrick J. Chem. Educ. 1990, 67, 167.
Thin Layer Chromatography
|
Microscale synthesis and analysis of a dipeptide Blatchly, Richard A.; Allen, Timothy R.; Bergstrom, Dirk T.; Shinozaki, Yuji
The synthesis of a dipeptide from its component amino acids and its analysis by chiral-phase thin-layer chromatography.
Blatchly, Richard A.; Allen, Timothy R.; Bergstrom, Dirk T.; Shinozaki, Yuji J. Chem. Educ. 1989, 66, 965.
Microscale Lab |
Synthesis |
Proteins / Peptides |
Thin Layer Chromatography |
Amino Acids
|
An investigation into the mechanism of the Ritter reaction Hathaway, Bruce A.
Students are asked to propose a reaction mechanism; experimentation then demonstrates the most reasonable proposal.
Hathaway, Bruce A. J. Chem. Educ. 1989, 66, 776.
Mechanisms of Reactions |
Thin Layer Chromatography
|
Photochemical and thermal isomerization of trans- and cis-1,2-dibenzoylethylene: A microscale approach Klemm, Dennis V; Tuncay, Atilla
Both conversions are analyzed through thin layer chromatography.
Klemm, Dennis V; Tuncay, Atilla J. Chem. Educ. 1989, 66, 519.
Photochemistry |
Stereochemistry |
Microscale Lab |
Thin Layer Chromatography |
Diastereomers
|
The analysis of ball-point inks for forensic purposes Breedlove, C. H.
The purpose of this paper is to describe the typical steps used in the analysis of ball point ink.
Breedlove, C. H. J. Chem. Educ. 1989, 66, 170.
Forensic Chemistry |
Thin Layer Chromatography
|
cis and trans-Stilbenes: Chromatographic separation and photochemical isomerization Levine, Samuel G.; Barhoriak, Kathleen Doubek; Cho, Ho S.
An organic chemistry laboratory that has historic significance.
Levine, Samuel G.; Barhoriak, Kathleen Doubek; Cho, Ho S. J. Chem. Educ. 1988, 65, 79.
Separation Science |
Photochemistry |
Diastereomers |
Chromatography
|
Analysis of aspartame and its hydrolysis products by thin-layer chromatography Conklin, Alfred R.
Separating and identifying the amino acids found in aspartame.
Conklin, Alfred R. J. Chem. Educ. 1987, 64, 1065.
Thin Layer Chromatography |
Amino Acids |
Food Science |
Separation Science |
Qualitative Analysis
|
Quantitative application of thin-layer chromatography in the analysis of organic compounds: Determining the molecular weights of 2,4-dinitrophenylhydrazones and dicarboxylic acids Giuliano, Vincenzo; Rieck, John Paul
This simple, easy, and inexpensive method provides a good illustration of the importance of polarity on solubility and a unique demonstration of the effectiveness of TLC as a quantitative tool.
Giuliano, Vincenzo; Rieck, John Paul J. Chem. Educ. 1987, 64, 625.
Thin Layer Chromatography |
Physical Properties |
Separation Science |
Quantitative Analysis
|
Hydrogen bonding and retention on silica: A concept illustrated by TLC chromatography of nitrophenols Feigenbaum, A.
The TLC experiments presented in this paper illustrate several important features regarding retention, elution, and selectivity on silica through the study of the chromatographic behavior of nitrophenols.
Feigenbaum, A. J. Chem. Educ. 1986, 63, 815.
Heterocycles |
Thin Layer Chromatography |
Acids / Bases |
Phenols |
Hydrogen Bonding
|
Thin-layer chromatographic separation of phenols Kurth, Mark J.
The structural complexity of typical TLC experiments precludes meaningful discussions of important aspects of TLC.
Kurth, Mark J. J. Chem. Educ. 1986, 63, 360.
Thin Layer Chromatography |
Phenols
|
Reverse-phase thin-layer chromatography Cooley, J. H.; Wong, A. L.
Reversing the polarity of the stationary and mobile phases enhances learning from the types of experiments profiled in this note.
Cooley, J. H.; Wong, A. L. J. Chem. Educ. 1986, 63, 353.
Thin Layer Chromatography |
Food Science
|
An inexpensive developing chamber for radial chromatography Gadwood, Robert C.
Design and advantages of a radial chromatography chamber.
Gadwood, Robert C. J. Chem. Educ. 1985, 62, 820.
Laboratory Equipment / Apparatus |
Chromatography |
Separation Science
|
An undergraduate organic experiment using thin-layer chromatography Jones, Taylor B.; Jones, Tappey H.
Separation of derivatives of aliphatic compounds, 2,4-dinitrophenylhydrazones.
Jones, Taylor B.; Jones, Tappey H. J. Chem. Educ. 1985, 62, 813.
Thin Layer Chromatography |
Separation Science
|
Synthesis and a simple molecular weight determination of polystyrene Armstrong, Daniel W.; Marx, John N.; Kyle, Don; Alak, Ala
Procedure for synthesizing styrene and determining its molecular weight using thin layer chromatography.
Armstrong, Daniel W.; Marx, John N.; Kyle, Don; Alak, Ala J. Chem. Educ. 1985, 62, 705.
Synthesis |
Polymerization |
Chromatography
|
Improvements in the separation of beta-carotene and lycopene by column chromtography Ronman, Peter
Modification of an existing laboratory procedure involving the separation of beta-carotene and lycopene by column chromtography.
Ronman, Peter J. Chem. Educ. 1985, 62, 540.
Chromatography |
Separation Science |
Thin Layer Chromatography
|
An inexpensive and quick method for demonstrating column chromatography of plant pigments of spinach extract Mewaldt, William; Rodolph, Dawn; Sady, Michael
Constructing a simple column chromatograph from a disposable pipet.
Mewaldt, William; Rodolph, Dawn; Sady, Michael J. Chem. Educ. 1985, 62, 530.
Chromatography |
Dyes / Pigments |
Separation Science
|
Gas chromatographic determination of fatty acid compositions Heinzen, Horacio; Moyna, Patrick; Grompone, Antonia
An experiment that includes a derivatization step and uses readily available reagents.
Heinzen, Horacio; Moyna, Patrick; Grompone, Antonia J. Chem. Educ. 1985, 62, 449.
Gas Chromatography |
Lipids |
Instrumental Methods |
Fatty Acids
|
Analytical chemistry program set Hardy, James K.
60. Bits and pieces, 23. A series of programs for use in the analytical laboratory.
Hardy, James K. J. Chem. Educ. 1985, 62, 411.
Gas Chromatography |
Titration / Volumetric Analysis |
UV-Vis Spectroscopy
|
TLC of organic dyes in undergraduate labs Sciam, Allen J.
Investigation into the effectiveness of varying the solvent composition in terms of resolving the components of a mixture of dyes using thin layer chromatography.
Sciam, Allen J. J. Chem. Educ. 1985, 62, 361.
Thin Layer Chromatography |
Dyes / Pigments |
Solutions / Solvents
|
Separation and identification of commonly used drugs: A thin-layer chromatography experiment for freshman chemistry Bonicamp, Judith M.
Using a simplified and accelerated TLC kit for drug detection.
Bonicamp, Judith M. J. Chem. Educ. 1985, 62, 160.
Separation Science |
Thin Layer Chromatography |
Drugs / Pharmaceuticals
|
An improved method for visualizing TLC plates using iodine Roberbon, John
Mixing iodine with silica gel and pouring it onto a thin layer chromatography plate for faster visualization.
Roberbon, John J. Chem. Educ. 1985, 62, 156.
Thin Layer Chromatography |
Laboratory Management |
Separation Science
|
High performance thin layer chromatography Costanzo, Samuel J.
Considers the various ways in which high performance has been achieved in thin layer chromatography, including the new TLC plates, sample application, plate development, and instrumental techniques.
Costanzo, Samuel J. J. Chem. Educ. 1984, 61, 1015.
HPLC |
Chromatography |
Separation Science |
Instrumental Methods
|
Chromatography: Use of a microcomputer to introduce laboratory techniques Holdsworth, David K.
54. Bits and pieces, 21. Program to introduce paper, thin-layer, column, and gas-liquid chromatography.
Holdsworth, David K. J. Chem. Educ. 1984, 61, 790.
Chromatography |
Separation Science |
Thin Layer Chromatography
|
A practical experiment for determining a pervasive, persistent pollutant Anderson, C. P.; Saner, W. A.
Spectral identification by means of infrareds spectroscopy of the PCBs recovered from a TLC plate is enhanced due to the concentrating effect of a commercial sample-recovery system.
Anderson, C. P.; Saner, W. A. J. Chem. Educ. 1984, 61, 738.
IR Spectroscopy |
Thin Layer Chromatography |
Separation Science |
Qualitative Analysis
|
An inexpensive experiment for the introduction of high performance liquid chromatography Bidlingmeyer, Brian A.; Warren, F. Vincent, Jr.
Separates the food dyes found in grape-flavored Kool-Aid using isocratic and gradient solution methods. [Debut]
Bidlingmeyer, Brian A.; Warren, F. Vincent, Jr. J. Chem. Educ. 1984, 61, 716.
Chromatography |
HPLC |
Separation Science |
Dyes / Pigments
|
A simple and inexpensive preparative TLC applicator Monti, Diego
Using normograph pens for ink applications.
Monti, Diego J. Chem. Educ. 1984, 61, 514.
Separation Science |
Thin Layer Chromatography |
Laboratory Equipment / Apparatus
|
Quick modification of a TLC plate by use of a disposable dipping chamber Marmer, William N.
Using a disposable polyethylene bag.
Marmer, William N. J. Chem. Educ. 1984, 61, 512.
Separation Science |
Laboratory Equipment / Apparatus |
Thin Layer Chromatography
|
Use of pseudophase TLC in teaching laboratories Armstrong, Daniel W.; Bui, Khanh H.; Barry, Regina M.
Thin-layer chromatography using micellar and alpha-cyclodextrin mobile phases.
Armstrong, Daniel W.; Bui, Khanh H.; Barry, Regina M. J. Chem. Educ. 1984, 61, 457.
Thin Layer Chromatography |
Separation Science |
Micelles
|
Investigating a mixture of polar and nonpolar compounds using the same thin-layer chromatography plate Somanathan, Ratnasamy
Avoids needing several thin layer plates.
Somanathan, Ratnasamy J. Chem. Educ. 1984, 61, 456.
Separation Science |
Thin Layer Chromatography
|
Chlorophyll separation and spectral identification Diehl-Jones, Susan M.
Extracting chlorophyl a and b from spinach and separating them using thin-layer and column chromatography.
Diehl-Jones, Susan M. J. Chem. Educ. 1984, 61, 454.
Separation Science |
Spectroscopy |
Plant Chemistry |
Photosynthesis |
Dyes / Pigments |
Thin Layer Chromatography |
Chromatography
|
Identification of unknown black inks by thin-layer chromatography Olesen, B.; Hopson, D.
A quick lab that will introduce students to TLC while demonstrating different properties and components of pen ink.
Olesen, B.; Hopson, D. J. Chem. Educ. 1983, 60, 232.
Thin Layer Chromatography |
Dyes / Pigments
|
Separation and determination of hydroxyacetophenones: An experiment in preparative TLC and UV spectroscopy Bick, I. R. C.; Blackman, A. J.; Browne, E. J.
A mixture of o-, m-, and p-hydroxyacetophenones is separated through thin-layer chromatography, and the constituents are identified by UV spectroscopy.
Bick, I. R. C.; Blackman, A. J.; Browne, E. J. J. Chem. Educ. 1982, 59, 618.
Separation Science |
Thin Layer Chromatography |
UV-Vis Spectroscopy |
Qualitative Analysis |
Quantitative Analysis
|
A simple and inexpensive preparative TLC applicator Lavallee, P.; Muzart, J.
A simple thin layer chromstography applicator that allows for the application of narrow streaks without holes or grooves, even when homemade plates are used.
Lavallee, P.; Muzart, J. J. Chem. Educ. 1982, 59, 250.
Thin Layer Chromatography |
Separation Science |
Laboratory Equipment / Apparatus
|
An inexpensive liquid chromatography apparatus for undergraduate teaching McCamish, Malcolm; Cannell, G. R.; Bretherton, L.
Description of a low-pressure liquid chromatography pump, slurry filler, stainless steel columns, and injector system suited to an undergraduate laboratory or routine analysis.
McCamish, Malcolm; Cannell, G. R.; Bretherton, L. J. Chem. Educ. 1982, 59, 249.
Chromatography |
Separation Science |
Laboratory Equipment / Apparatus
|
Isolation, separation and identification of synthetic food colors Dixon, E. A.; Renyk, G.
A simple, inexpensive experiment for the extraction of synthetic dyes permitted in foodstuffs, and their separation and identification using thin-layer chromatography and ultraviolet/visible spectroscopy.
Dixon, E. A.; Renyk, G. J. Chem. Educ. 1982, 59, 67.
Separation Science |
Food Science |
Chromatography |
Thin Layer Chromatography |
Consumer Chemistry |
UV-Vis Spectroscopy |
Qualitative Analysis
|
A simple method for sample application in chromatography Lo, J. M.
A simple applicator made of a rubber bulb and glass capillary tube.
Lo, J. M. J. Chem. Educ. 1982, 59, 66.
Chromatography |
Laboratory Equipment / Apparatus |
Separation Science
|
Analysis of analgesic mixtures: An organic chemistry experiment Martin, Ned H.
The lab described here allows for students to work out experimental conditions themselves and introduces semi-micro techniques.
Martin, Ned H. J. Chem. Educ. 1981, 58, 818.
Microscale Lab |
Thin Layer Chromatography |
UV-Vis Spectroscopy |
IR Spectroscopy |
Spectroscopy
|
An inorganic laboratory experiment involving photochemistry, liquid chromatography, and infrared spectroscopy Post, Elroy W.
An experiment involving photochemical ligand displacement on a metal carbonyl, separation of the product by mixture by chromatography, and identification of the components using IR spectroscopy and group theory.
Post, Elroy W. J. Chem. Educ. 1980, 57, 819.
Photochemistry |
Chromatography |
IR Spectroscopy |
Group Theory / Symmetry |
Separation Science
|
Thin layer chromatographic separation of common analgesics-a comment Roswell, D. F.; Zaczek, N. M.
The authors were unable to resolve phenacetin and salicylamide using a three component solvent system.
Roswell, D. F.; Zaczek, N. M. J. Chem. Educ. 1979, 56, 834.
Chromatography |
Separation Science |
Thin Layer Chromatography |
Drugs / Pharmaceuticals
|
An organic chemistry experiment for forensic science majors Rothchild, Robert
Qualitative analysis of over-the-counter analgesics using thin-layer chromatography.
Rothchild, Robert J. Chem. Educ. 1979, 56, 757.
Forensic Chemistry |
HPLC |
Chromatography |
Medicinal Chemistry |
Qualitative Analysis |
Separation Science
|
Two sample applicators for chromatography Malik, N. S. A.; Berrie, A. M. M.
Designs for two thin layer chromatography applicators that can be made with a minimum of workshop facilities are described, one for small syringes and the other for larger syringes.
Malik, N. S. A.; Berrie, A. M. M. J. Chem. Educ. 1979, 56, 680.
Chromatography |
Laboratory Equipment / Apparatus |
Thin Layer Chromatography |
Separation Science
|
The rapid isolation of carotenoids from foods McKone, Harold T.
Isolating carotene and lycopene from carrots and tomato paste without heating the organic solvents, and eliminating grinding with sand for the isolation of carotenoids from citrus fruit skins.
McKone, Harold T. J. Chem. Educ. 1979, 56, 676.
Separation Science |
Chromatography
|
A student synthesis of the housefly sex attractant Cormier, Russell A.; Duc Phan, M.; Graddis, Thomas; Singer, Richard
This multi-step synthetic sequence illustrates several important laboratory techniques, including ir and nmr spectroscopy, thin-layer and column chromatography, rotary evaporation, recrystallization, and vacuum distillation.
Cormier, Russell A.; Duc Phan, M.; Graddis, Thomas; Singer, Richard J. Chem. Educ. 1979, 56, 345.
Synthesis |
Natural Products |
IR Spectroscopy |
NMR Spectroscopy |
Chromatography |
Thin Layer Chromatography
|
A method to prevent septum bleeding in high temperature gas chromatography Lafosse, M.
Applying a porous Teflon frit to prevent septum bleeding in high temperature gas chromatography.
Lafosse, M. J. Chem. Educ. 1979, 56, 202.
Gas Chromatography |
Laboratory Equipment / Apparatus |
Laboratory Management
|
Z- and E-stereoisomerism: An experiment using photochemistry Bourelle-Wargnier, F.; Feigenbaum, A.; Muzart, J.
The authors' report on the preparation of 2-benzylidenecyclohexanone E(I).
Bourelle-Wargnier, F.; Feigenbaum, A.; Muzart, J. J. Chem. Educ. 1978, 55, 339.
Stereochemistry |
Photochemistry |
Aromatic Compounds |
Thin Layer Chromatography |
IR Spectroscopy |
Enantiomers
|
Computer simulation in organic chemistry - Thin layer chromatography Bond, Douglas
The author shares his trials and victories in attempting to produce first class organic chemists.
Bond, Douglas J. Chem. Educ. 1978, 55, 323.
Thin Layer Chromatography
|
A sample preparation technique for column chromatography Beller, Nicholas R.; Hilleary, Christopher J.
The authors have found a simple and effective method of sample preparation for use in column chromatography which resembles the application of a sample to a thin layer chromatography plate, where the solid sample in solution is absorbed by the solid phase as the solvent evaporates.
Beller, Nicholas R.; Hilleary, Christopher J. J. Chem. Educ. 1976, 53, 498.
Thin Layer Chromatography |
Solutions / Solvents |
Phases / Phase Transitions / Diagrams |
Solid State Chemistry
|
Photooxidation of methionine. An integrated organic-analytical-biochemistry laboratory experiment Lewis, Catherine; Scouten, William H.
The experiments presented here familiarize the student with the organic reactions necessary to prepare the starting material; introduces the use of glass beads for immobilizing a catalyst; demonstrates the use of light and methylene blue as oxidizers; requires the implementation of an important analytical technique, thin layer chromatography; provides the student with a good example of the reactivity of one amino acid, methionine.
Lewis, Catherine; Scouten, William H. J. Chem. Educ. 1976, 53, 395.
Thin Layer Chromatography |
Amino Acids |
Laboratory Equipment / Apparatus |
Catalysis
|
TLC analysis of carbaryl insecticide on sprayed foliage. A student experiment Bidleman, T. F.; Rice, C. P.
The authors develop a relevant lab experience in order to introduce students to thin layer chromatography.
Bidleman, T. F.; Rice, C. P. J. Chem. Educ. 1976, 53, 173.
Thin Layer Chromatography |
Toxicology |
Hormones |
Quantitative Analysis
|
A novel method for quantitative thin layer chromatography Baum, D. E.; Shanks, R. A.
Weighing cut out spot images from thin layer chromatograms.
Baum, D. E.; Shanks, R. A. J. Chem. Educ. 1975, 52, 738.
Thin Layer Chromatography |
Chromatography |
Quantitative Analysis
|
Helpful TLC techniques Martin, Ned H.
Procedure for obtaining a uniformly thick adsorbent layer on chromatography plates and locating zones on thin layer chromatography plates.
Martin, Ned H. J. Chem. Educ. 1975, 52, 467.
Chromatography |
Separation Science |
Thin Layer Chromatography |
Laboratory Management
|
An integrated synthesis laboratory for the sophomore year Pearson, Wesley A.; Finholt, Albert E.
Outlines the compounds synthesized and the techniques used in a two-semester integrated laboratory sequence for sophomores.
Pearson, Wesley A.; Finholt, Albert E. J. Chem. Educ. 1975, 52, 236.
Synthesis |
Coordination Compounds |
IR Spectroscopy |
NMR Spectroscopy |
UV-Vis Spectroscopy |
Chromatography
|
Thin-layer chromatogram visualization. A student experiment Madsen, Brooks C.
This thin layer chromatography experiment separates mixtures of common over the counter analgesics and antipyretic preparations and related compounds, and has several advantages that many student oriented tlc experiments lack.
Madsen, Brooks C. J. Chem. Educ. 1973, 50, 852.
Thin Layer Chromatography |
Chromatography |
Separation Science
|
Determining the molecular weight of N-fatty acids by thin layer chromatography Singh, Eric J.; Zuspan, Frederick P.
Simple procedure for determining the molecular weight of N-fatty acids by thin layer chromatography.
Singh, Eric J.; Zuspan, Frederick P. J. Chem. Educ. 1973, 50, 625.
Molecular Properties / Structure |
Physical Properties |
Thin Layer Chromatography |
Chromatography |
Fatty Acids
|
The determination of pesticide residues. A laboratory experiment Jarosch, Richard
The determination of pesticide residues using thin-layer and gas chromatography.
Jarosch, Richard J. Chem. Educ. 1973, 50, 507.
Chromatography |
Thin Layer Chromatography |
Gas Chromatography |
Separation Science
|
"Dry-column" chromatography. A new technique for the undergraduate laboratory Bohen, J. M.; Joullie, M. M.; Kaplan, F. A.; Loev, B.
In this experiment, thin-layer chromatography is used to determine the number of compounds in a prepared dye mixture and "dry-column" chromatography is used to separate the mixture into its components.
Bohen, J. M.; Joullie, M. M.; Kaplan, F. A.; Loev, B. J. Chem. Educ. 1973, 50, 367.
Chromatography |
Separation Science |
Thin Layer Chromatography |
Dyes / Pigments
|
An investigation of sebum and other facial lipids Calsin, Dennis; Trinler, W. A.
An introductory thin layer chromatography experiment that illustrates the variety of surface facial lipids, produced chiefly by sebaceous glands.
Calsin, Dennis; Trinler, W. A. J. Chem. Educ. 1973, 50, 135.
Thin Layer Chromatography |
Chromatography |
Separation Science |
Lipids |
Natural Products
|
TLC detection of caffeine in commercial products Pavlik, James W.
An introductory experiment that involves the thin layer chromatography detection of caffeine in a variety of familiar pharmaceutical products.
Pavlik, James W. J. Chem. Educ. 1973, 50, 134.
Thin Layer Chromatography |
Chromatography |
Separation Science |
Consumer Chemistry |
Drugs / Pharmaceuticals |
Qualitative Analysis
|
Geometry in chromatography Campbell, Bruce Henry
This paper reports investigations into conical chromatography and the advantages and disadvantages of such a geometry.
Campbell, Bruce Henry J. Chem. Educ. 1973, 50, 133.
Chromatography |
Separation Science
|
The thin-layer chromatography of drugs. A laboratory experiment Neman, R. L.
Students are introduced to thin layer chromatography, are provided samples known to contain alkaloids and barbiturates, separate the mixtures using tlc, determine the components of their unknowns, and calculate Rf values for the components.
Neman, R. L. J. Chem. Educ. 1972, 49, 834.
Chromatography |
Thin Layer Chromatography |
Separation Science |
Drugs / Pharmaceuticals
|
Partial analysis of vinyl-asbestos floor tile. A tlc experiment for beginning organic chemistry Foreman, William A.; Paulson, Donald R.
This laboratory introduces thin-layer chromatography while presenting the student with a typical industrial analysis problem.
Foreman, William A.; Paulson, Donald R. J. Chem. Educ. 1972, 49, 572.
Industrial Chemistry |
Thin Layer Chromatography |
Separation Science
|
Quick paper chromatography of amino acids Heimer, E. P.
Applies acetonitrile-buffer systems for the relatively rapid separation of amino acids.
Heimer, E. P. J. Chem. Educ. 1972, 49, 547.
Chromatography |
Separation Science |
Amino Acids
|
Small-scale thin-layer chromatography. Experiments for teaching purposes Brinkman, U. A. Th.; De Vries, G.
Describes a number of rapid thin-layer chromatography separations that can be conveniently used to introduce chromatography in the teaching laboratory.
Brinkman, U. A. Th.; De Vries, G. J. Chem. Educ. 1972, 49, 545.
Thin Layer Chromatography |
Chromatography |
Microscale Lab |
Separation Science
|
Column and thin-layer chromatography. A combined experiment for the undergraduate organic laboratory Ruppel, Irving B., Jr.; Cuneo, Frederick L.; Krause, Josef G.
The authors have been using the product mixture obtained from the nitration of phenol to demonstrate the techniques of column and thin-layer chromatography with excellent results. The authors feel the experiment has several advantages over the column chromatographic experiments usually described in undergraduate laboratory manuals.
Ruppel, Irving B., Jr.; Cuneo, Frederick L.; Krause, Josef G. J. Chem. Educ. 1971, 48, 635.
Thin Layer Chromatography
|
Analysis of APC tablets. An inexpensive and practical thin-layer chromatography experiment Lieu, Van T.
By using a commercial item, students are faced with a "live" problem connected with everyday living.
Lieu, Van T. J. Chem. Educ. 1971, 48, 478.
Thin Layer Chromatography |
Chromatography
|
Chemical separation methods (Dean, John A.) Culp, Robert A.
Culp, Robert A. J. Chem. Educ. 1970, 47, A396.
Separation Science |
Chromatography
|
Chromatography (Browning, D. R.) Karger, Barry L.
Karger, Barry L. J. Chem. Educ. 1970, 47, A306.
Chromatography |
Separation Science
|
Instrumental methods of chemical analysis (Ewing, Galen) Safford, H. W.
Safford, H. W. J. Chem. Educ. 1970, 47, A128.
Instrumental Methods |
Spectroscopy |
Chromatography
|
Separation of leucine and isoleucine by thin-layer chromatography Gatto, Karen L.; Borders, C. L., Jr.
This experiment involves the separation of leucine and isoleucine through continuous ascending thin layer chromatography.
Gatto, Karen L.; Borders, C. L., Jr. J. Chem. Educ. 1970, 47, 840.
Separation Science |
Thin Layer Chromatography |
Chromatography |
Amino Acids |
Constitutional Isomers
|
A simple streaker for preparative layer chromatography Altman, L. J.; Trudell, James R.
Presents a simple streaker for preparative layer chromatography and explains its use.
Altman, L. J.; Trudell, James R. J. Chem. Educ. 1970, 47, 404.
Chromatography |
Separation Science |
Laboratory Equipment / Apparatus
|
Adsorbent extractor for preparative thin-layer chromatography Hansbury, Elizabeth; Ott, Donald G.
Device to remove sample containing regions from cellulose thin-layer chromatograms and extract the samples that eliminates many of the problems associated with other methods.
Hansbury, Elizabeth; Ott, Donald G. J. Chem. Educ. 1970, 47, 229.
Thin Layer Chromatography |
Laboratory Equipment / Apparatus |
Separation Science
|
A short, intensive experiment in paper chromatography McCullough, Thomas; Lechtenberg, Andre
A paper chromatographic system capable of separating a challenging mixture of components (amino acids) in less than three hours.
McCullough, Thomas; Lechtenberg, Andre J. Chem. Educ. 1970, 47, 141.
Chromatography |
Separation Science |
Amino Acids
|
A versatile and compact chromatographic chamber Lehrfeld, J.
This simple and inexpensive glass chamber facilitates thin-layer chromatography separations of a large number of samples within 5 minutes.
Lehrfeld, J. J. Chem. Educ. 1969, 46, 848.
Laboratory Equipment / Apparatus |
Separation Science |
Thin Layer Chromatography
|
A simple, inexpensive zone extractor for preparative thin-layer chromatography Kan, G.; Snieckus, V.
This short note presents the design of a simple, inexpensive zone extractor for preparative thin-layer chromatography.
Kan, G.; Snieckus, V. J. Chem. Educ. 1969, 46, 763.
Chromatography |
Separation Science |
Laboratory Equipment / Apparatus
|
An introduction to chromatography Gaucher, G. M.
The object of this presentation is to serve as a preliminary practical introduction and guide to chromatography.
Gaucher, G. M. J. Chem. Educ. 1969, 46, 729.
Chromatography |
Separation Science |
Thin Layer Chromatography |
Gas Chromatography |
Ion Exchange
|
Reflectance spectroscopic analysis of dyes separated by thin layer chromatography Frodyma, M. M.; Frei, R. W.
This study attempts to verify the usefulness of reflectance spectroscopy as an analytical tool in the hands of the inexperienced analyst.
Frodyma, M. M.; Frei, R. W. J. Chem. Educ. 1969, 46, 522.
Spectroscopy |
Dyes / Pigments |
Thin Layer Chromatography |
Qualitative Analysis |
Quantitative Analysis
|
Simple developing chamber for thin layer chromatography Aronson, John N.
This short note describes the design of a simple developing chamber for thin layer chromatography.
Aronson, John N. J. Chem. Educ. 1969, 46, 483.
Laboratory Equipment / Apparatus |
Thin Layer Chromatography |
Chromatography |
Separation Science
|
Modifications of solution chromatography illustrated with chloroplast pigments Strain, Harold H.; Sherma, Joseph
Using plant pigments to demonstrate various chromatographic techniques, including column adsorption, paper adsorption, paper partition, column partition, and thin layer chromatography.
Strain, Harold H.; Sherma, Joseph J. Chem. Educ. 1969, 46, 476.
Chromatography |
Separation Science |
Plant Chemistry |
Dyes / Pigments |
Natural Products |
Thin Layer Chromatography
|
The photoisomerization of azobenzene: A TLC experiment for the undergraduate organic laboratory Janssen, Jerry F.
The photoisomerization of azobenzene provides a rare opportunity to explore molecular photochemistry in undergraduate organic chemistry.
Janssen, Jerry F. J. Chem. Educ. 1969, 46, 117.
Chromatography |
Thin Layer Chromatography |
Photochemistry |
Diastereomers
|
Column chromatography spectrometry for separating two cobalt complexes: A laboratory experiment Schmitt, Donald L.; Jonassen, Hans B.
This paper presents the details of the separation of [Co(NH3)6]Cl3 from [Co(NH3)5]Cl2 using molecular sieves.
Schmitt, Donald L.; Jonassen, Hans B. J. Chem. Educ. 1969, 46, 47.
Chromatography |
Spectroscopy |
Separation Science |
Coordination Compounds
|
Cylindrical thin-layer chromatography Jordan, David
This short note describes the use and advantages of cylindrical thin-layer chromatography.
Jordan, David J. Chem. Educ. 1968, 45, 510.
Chromatography |
Thin Layer Chromatography |
Separation Science |
Dyes / Pigments
|
The use of cellophane sheets for direct reading and recording of Rf values Chortyk, O. T.; Kushnir, I.
Describes the use of cellophane sheets for direct reading and recording of Rf values.
Chortyk, O. T.; Kushnir, I. J. Chem. Educ. 1968, 45, 506.
Chromatography |
Thin Layer Chromatography |
Separation Science
|
A simple sprayer for quantitative thin-layer chromatography Samuels, Stanley
A simple, inexpensive sprayer for chromatographic use that can be constructed by a student as a laboratory project.
Samuels, Stanley J. Chem. Educ. 1968, 45, 438.
Laboratory Equipment / Apparatus |
Thin Layer Chromatography |
Chromatography |
Separation Science
|
A simplified slotted lid for preparative thin-layer chromatography jars Borka, Laszlo
Design for an all-glass lid for preparative thin-layer chromatography jars.
Borka, Laszlo J. Chem. Educ. 1968, 45, 401.
Laboratory Equipment / Apparatus |
Separation Science |
Thin Layer Chromatography |
Chromatography
|
An inexpensive sprayer for chromatography DeThomas, Anthony V.; Pascual, Francis
This short note presents a simple and inexpensive sprayer for paper and thin-layer chromatography.
DeThomas, Anthony V.; Pascual, Francis J. Chem. Educ. 1968, 45, 321.
Laboratory Equipment / Apparatus |
Chromatography |
Separation Science
|
An inexpensive device for evaluating solvents for paper and thin-layer chromatography DeThomas, Anthony V.; Pascual, Francis
A short note describing a device for evaluating solvents used to develop paper and thin-layer chromatograms.
DeThomas, Anthony V.; Pascual, Francis J. Chem. Educ. 1968, 45, 303.
Separation Science |
Chromatography |
Thin Layer Chromatography |
Laboratory Equipment / Apparatus |
Solutions / Solvents
|
Analytical chemistry Rogers, L. B.
Many of the guiding principles for optimizing chromatographic separations are appropriate for inclusion in an undergraduate analytical course.
Rogers, L. B. J. Chem. Educ. 1968, 45, 7.
Separation Science |
Chromatography
|
Thin-layer chromatography (Randerath, Kurt) Malins, Donald C.
Malins, Donald C. J. Chem. Educ. 1967, 44, A912.
Chromatography |
Thin Layer Chromatography |
Separation Science
|
Chromatographic methods (Stock, R.) Sherma, Joseph
Sherma, Joseph J. Chem. Educ. 1967, 44, 624.
Chromatography |
Separation Science
|
Test tube and glass rod tlc Ikan, Raphael; Rapaport, Eliezer
Describes the use of test tubes and glass rods coated on their outer surfaces for thin layer chromatography.
Ikan, Raphael; Rapaport, Eliezer J. Chem. Educ. 1967, 44, 297.
Thin Layer Chromatography |
Chromatography |
Separation Science
|
The use of talc as a tlc adsorbent Walsh, Brother Joseph M.
Describes the use of talc as a thin layer chromatography adsorbent, particularly with respect to the separation of flavonoids, sugars, and proteins.
Walsh, Brother Joseph M. J. Chem. Educ. 1967, 44, 294.
Thin Layer Chromatography |
Chromatography |
Separation Science |
Proteins / Peptides |
Carbohydrates
|
Zone extractor for thin-layer chromatography Ruchelman, Maryon W.
This communication describes a simple technique for elution columns prepared from commercially available disposable capillary pipets.
Ruchelman, Maryon W. J. Chem. Educ. 1967, 44, 110.
Laboratory Equipment / Apparatus |
Chromatography |
Thin Layer Chromatography |
Separation Science
|
A simple apparatus for scoring tlc plates Walsh, Brother Joseph M.
Describes a simple apparatus for scoring thin layer chromatography plates.
Walsh, Brother Joseph M. J. Chem. Educ. 1967, 44, 24.
Chromatography |
Thin Layer Chromatography |
Separation Science |
Laboratory Equipment / Apparatus
|
Optimizing experimental conditions: The use of TLC to follow the course of a reaction Herz, Joseph E.
A student research project that relies on the acetylation of ferrocene to illustrate the use of thin-layer chromatography to follow the course of a reaction.
Herz, Joseph E. J. Chem. Educ. 1966, 43, 599.
Chromatography |
Thin Layer Chromatography
|
Resolution in linear elution chromatography Karger, Barry L.
Examines fundamentals of resolution that are common to all chromatographic methods.
Karger, Barry L. J. Chem. Educ. 1966, 43, 47.
Chromatography |
Separation Science
|
Homemade marker for chromatography plates Miller, Frederick W.
Presents a marker for chromatography plates constructed from a pocket comb.
Miller, Frederick W. J. Chem. Educ. 1966, 43, 29.
Thin Layer Chromatography |
Chromatography |
Laboratory Equipment / Apparatus |
Separation Science
|
Determining the carbon number of n-fatty acids by TLC Singh, Eric J.; Gershbein, Leon L.
Presents a method for determining the carbon number of n-fatty acids through thin layer chromatography.
Singh, Eric J.; Gershbein, Leon L. J. Chem. Educ. 1966, 43, 29.
Thin Layer Chromatography |
Chromatography
|
A spreader for TLC slides Whistler, Roy L.; Lamchen, Max; Rowell, R. M.
Presents a spreader for thin layer chromatography slides made from Plexiglass sheets.
Whistler, Roy L.; Lamchen, Max; Rowell, R. M. J. Chem. Educ. 1966, 43, 28.
Laboratory Equipment / Apparatus |
Thin Layer Chromatography |
Chromatography |
Separation Science
|
Thin-layer chromatography: A laboratory handbook (Stahl, Egon) Malins, Donald C.
Malins, Donald C. J. Chem. Educ. 1965, 42, 692.
Chromatography |
Thin Layer Chromatography |
Separation Science
|
Use of the unopette in thin-layer chromatography Clitheroe, H. J.; Gerarde, H. W.
Describes the use of the Unopette capillary in applying samples to chromatographic plates.
Clitheroe, H. J.; Gerarde, H. W. J. Chem. Educ. 1965, 42, 613.
Chromatography |
Thin Layer Chromatography |
Separation Science |
Laboratory Equipment / Apparatus
|
An inexpensive TLC tank Andersen, Kenneth K.; May, George S.
Presents a sandwich-type thin layer chromatography tank.
Andersen, Kenneth K.; May, George S. J. Chem. Educ. 1965, 42, 596.
Chromatography |
Thin Layer Chromatography |
Separation Science |
Laboratory Equipment / Apparatus
|
Natural product chemistry: Laboratory research approach for elementary organic courses O'Connor, Rod
Describes a program designed to introduce macro, semi-micro, and micro techniques of organic chemistry of the types commonly employed in research in natural product chemistry or in biologically-related fields.
O'Connor, Rod J. Chem. Educ. 1965, 42, 492.
Natural Products |
Undergraduate Research |
Separation Science |
Chromatography |
Thin Layer Chromatography |
Synthesis
|
Experiments in inorganic paper chromatography Walton, Harold F.
Experiments typical of those done in geochemical work involve the detection and estimation of uranium, copper, cobalt, and nickel.
Walton, Harold F. J. Chem. Educ. 1965, 42, 477.
Chromatography |
Separation Science |
Geochemistry |
Metals
|
Cation analysis with thin layer chromatography Goller, Edwin J.
Reported here is an adaptation of thin layer chromatography to an undergraduate laboratory operation for cation analysis.
Goller, Edwin J. J. Chem. Educ. 1965, 42, 442.
Chromatography |
Thin Layer Chromatography |
Qualitative Analysis
|
Instrumentation teaching equipment. Part three: Miscellaneous Eisner, Leonard
Considers magnetic resonance spectroscopy, magnetic susceptibility, atomic beam spectroscopy, mass spectrometers, chromatography, electrochemistry, electron diffraction, field emission microscopes, glass blowing and vacuum systems, high and low temperatures, and ultrasonics.
Eisner, Leonard J. Chem. Educ. 1964, 41, A607.
NMR Spectroscopy |
Spectroscopy |
Instrumental Methods |
Mass Spectrometry |
Magnetic Properties |
Chromatography |
Electrochemistry |
Laboratory Equipment / Apparatus
|
Thin layer chromatography (Bobbitt, James M.) Wollish, E. G.
Wollish, E. G. J. Chem. Educ. 1964, 41, A396.
Separation Science |
Chromatography |
Thin Layer Chromatography
|
Electrophoresis using thin layer materials Criddle, W. J.; Moody, G. J.; Thomas, J. D. R.
Thin layer materials prepared for chromatography are used for electrophoresis.
Criddle, W. J.; Moody, G. J.; Thomas, J. D. R. J. Chem. Educ. 1964, 41, 609.
Electrochemistry |
Electrophoresis |
Separation Science |
Thin Layer Chromatography
|
Chromatographic glossary Lewin, S. Z.
Presents thin layer and gas chromatography terms in English, German, French, and Spanish.
Lewin, S. Z. J. Chem. Educ. 1963, 40, A167.
Chromatography |
Separation Science |
Nomenclature / Units / Symbols |
Thin Layer Chromatography |
Gas Chromatography
|
TLC separation of ink pigments Druding, Leonard F.
The separation of inks into their component pigments was chosen for its simplicity in illustrating techniques and choice of solvent for thin layer chromatography; it also affords the student the opportunity to visually observe the course of the separation.
Druding, Leonard F. J. Chem. Educ. 1963, 40, 536.
Dyes / Pigments |
Chromatography |
Separation Science |
Thin Layer Chromatography
|
TLC on microscope slides: An organic chemistry experiment Naff, M. Benton; Naff, Anna S.
This experiment consists of three sections: separation of known and unknown dye mixtures; separation of known and unknown mixtures of phenols; separation of dyes and impurities.
Naff, M. Benton; Naff, Anna S. J. Chem. Educ. 1963, 40, 534.
Chromatography |
Thin Layer Chromatography |
Separation Science |
Dyes / Pigments |
Phenols
|
TLCVersatile tool Malins, Donald C.; Wekell, John C.
Examines apparatus and techniques, lecture demonstrations, laboratory experiments and general applications associated with thin layer chromatography.
Malins, Donald C.; Wekell, John C. J. Chem. Educ. 1963, 40, 531.
Chromatography |
Thin Layer Chromatography |
Separation Science
|
Thin layer chromatography apparatus Hansbury, Elizabeth; Ott, D. G.; Perrings, J. D.
Describes the preparation of the grooved plate and adsorbent layer for a simple and inexpensive, thin layer chromatography apparatus.
Hansbury, Elizabeth; Ott, D. G.; Perrings, J. D. J. Chem. Educ. 1963, 40, 31.
Thin Layer Chromatography |
Chromatography |
Laboratory Equipment / Apparatus
|
Separation of plant pigments by thin layer chromatography Anwar, M. H.
Describes a lab activity to separate chloroplast pigments over a thin layer of silicic acid.
Anwar, M. H. J. Chem. Educ. 1963, 40, 29.
Separation Science |
Plant Chemistry |
Thin Layer Chromatography |
Chromatography
|
Gas Chromatographs (continued) Lewin, S. Z.
Examines the nature of the packing in a gas chromatograph and its effects on the performance of the instrument.
Lewin, S. Z. J. Chem. Educ. 1962, 39, A5.
Gases |
Gas Chromatography |
Chromatography |
Separation Science |
Instrumental Methods
|
Chromatographic equipment (concluded) Lewin, S. Z.
Examines high voltage pherographs, column electrophoresis, thin-layer chromatographs, photometric effluent sensing systems, and refractometric effluent sensors.
Lewin, S. Z. J. Chem. Educ. 1961, 38, A789.
Instrumental Methods |
Chromatography |
Separation Science
|
Chromatographic equipment (continued) Lewin, S. Z.
Examines the following topics: design considerations for stabilized medium pherographs, specialized types of pherographs, continuous flow electrochromatographs, the continuous flow chromatograph, and fraction collectors.
Lewin, S. Z. J. Chem. Educ. 1961, 38, A713.
Chromatography |
Instrumental Methods |
Separation Science
|
Gas chromatography: Basic principles and new developments Pecsok, Robert L.
Summarizes some of the basic principles of and new apparatus for gas chromatography.
Pecsok, Robert L. J. Chem. Educ. 1961, 38, 212.
Chromatography |
Gas Chromatography |
Gases
|
|
