TIGER

Journal Articles: 22 results
Molecules and Medicine (E. J. Corey, Barbara Czakó, and László Kürti)  Robert E. Buntrock
Looking for a book on common drugs and pharmaceuticals? On diseases and medical conditions? On pharmacology? In addition, do you need some background in chemistry to handle all of this information? If you want all of this, and in addition want it under one cover, then this is the book for you.
Buntrock, Robert E. J. Chem. Educ. 2008, 85, 1495.
Bioorganic Chemistry |
Drugs / Pharmaceuticals |
Molecular Properties / Structure |
Proteins / Peptides |
Synthesis |
Toxicology
OMLeT—An Alternative Approach to Learning Metabolism: Glycolysis and the TCA Cycle as an Example  Charles M. Stevens, Dylan M. Silver, Brad Behm, Raymond J. Turner, and Michael G. Surette
Using PHP Hypertext Preprocessor scripting, the dynamic OMLeT (Online Metabolism Learning Tool) Web site is geared towards different learning styles and allows the student to process metabolic pathways (glycolysis and TCA cycle) via a user-defined approach.
Stevens, Charles M.; Silver, Dylan M.; Behm, Brad; Turner, Raymond J.; Surette, Michael G. J. Chem. Educ. 2007, 84, 2024.
Bioenergetics |
Enzymes |
Learning Theories |
Metabolism |
Proteins / Peptides
Caught on Tape: Catalyst Recovery; Secondary Structure Switch; DNA-Based Chiral Catalysts   Angela G. King
Common lab tape aids catalyst delivery and recovery, DNA lends its chirality to organic reaction, and a model for studying the transformation of ahelices to ?sheets.
King, Angela G. J. Chem. Educ. 2006, 83, 10.
Catalysis |
Chirality / Optical Activity |
Proteins / Peptides |
Molecular Modeling |
Molecular Properties / Structure
A "Polypeptide Demonstrator"  Addison Ault
I have used a telephone Handset Coil Cord as a simple and convenient model for the structure of a polypeptide.
Ault, Addison. J. Chem. Educ. 2004, 81, 196.
Proteins / Peptides |
Molecular Modeling |
Molecular Properties / Structure
Food: The Chemistry of Its Components, 4th Edition (T. P. Coultrate)  Richard Pagni
The book begins with an extensive discussion of the major constituents of food: sugars and their polymers, lipids, and amino acids and their polymers. This is followed by fascinating chapters on colors and flavors, the ingredients that do so much to make food enjoyable.
Pagni, Richard. J. Chem. Educ. 2004, 81, 39.
Consumer Chemistry |
Food Science |
Applications of Chemistry |
Carbohydrates |
Proteins / Peptides |
Lipids
Some Like It Cold: A Computer-Based Laboratory Introduction to Sequence and Tertiary Structure Comparison of Cold-Adapted Lactate Dehydrogenases Using Bioinformatics Tools  M. Sue Lowery and Leigh A. Plesniak
Students download sequences and structures from appropriate databases, create sequence alignments, and carry out molecular modeling exercises, and then form hypotheses about the mechanism of biochemical adaptation for function and stability. This laboratory is appropriate for biochemistry and molecular biology laboratory courses, special topics, and advanced biochemistry lecture courses, and can be adapted for honors high school programs.
Lowery, M. Sue; Plesniak, Leigh A. J. Chem. Educ. 2003, 80, 1300.
Enzymes |
Molecular Modeling |
Proteins / Peptides |
Molecular Properties / Structure
Protein Design Using Unnatural Amino Acids  Basar Bilgiçer and Krishna Kumar
Using examples from the literature, this article describes the available methods for unnatural amino acid incorporation and highlights some recent applications including the design of hyperstable protein folds.
Bilgiçer, Basar; Kumar, Krishna. J. Chem. Educ. 2003, 80, 1275.
Amino Acids |
Bioorganic Chemistry |
Biotechnology |
Proteins / Peptides |
Synthesis |
Molecular Properties / Structure
Factors Affecting Reaction Kinetics of Glucose Oxidase  Kristin A. Johnson
Demonstration based on a biochemical kinetics experiment in which the rate of reaction varies with the enzyme concentration, substrate concentration, substrate used in the reaction, and temperature.
Johnson, Kristin A. J. Chem. Educ. 2002, 79, 74.
Enzymes |
Kinetics |
Proteins / Peptides |
Carbohydrates |
Catalysis |
Rate Law
Protein Structure Wordsearch  Terry L. Helser
Puzzle with 37 names, terms, prefixes, and acronyms that describe protein structure.
Helser, Terry L. J. Chem. Educ. 2001, 78, 474.
Proteins / Peptides |
Nomenclature / Units / Symbols |
Molecular Properties / Structure
Microburger Biochemistry: Extraction and Spectral Characterization of Myoglyobin from Hamburger  Sheri A. Bylkas and Laura A. Andersson
The protocol combines protein extraction, oxidation and reduction, and simple spectroscopic analysis, as well as gel filtration chromatography and generation/analysis of spectral scans. Mammalian myoglobin (Mb) is easily extracted from steak, to illustrate and address why fresh meat is red and aged meat is brown; the protein has unique spectral properties that are diagnostic for characterization of sample identity.
Bylkas, Sheri A.; Andersson, Laura A. J. Chem. Educ. 1997, 74, 426.
Laboratory Equipment / Apparatus |
Proteins / Peptides |
Oxidation / Reduction |
UV-Vis Spectroscopy |
Chromatography
A Ligand-Binding Study Based on a Protein Assay Method  Chial, H. J.; Congdon, R. W.; Splittgerber, A. G.
Experimental procedure for determining the protein concentration of an unknown solution, as well as the number of dye-binding sites on the protein; data and analysis included.
Chial, H. J.; Congdon, R. W.; Splittgerber, A. G. J. Chem. Educ. 1995, 72, 76.
Proteins / Peptides |
Coordination Compounds |
Crystal Field / Ligand Field Theory
Use of Tangle Links To Show Globular Protein Structure  Marino, Francis
Using Tangle Links (a child's toy) to model the primary, secondary, tertiary, and quaternary structure of proteins.
Marino, Francis J. Chem. Educ. 1994, 71, 741.
Proteins / Peptides |
Molecular Modeling
Effects of "crowding" in protein solutions  Ralston, G. B.
The effects of macromolecular nonideality and crowding on chemical equilibria, association reactions, and enzyme kinetics.
Ralston, G. B. J. Chem. Educ. 1990, 67, 857.
Proteins / Peptides |
Equilibrium |
Reactions |
Enzymes |
Kinetics
Lecture demonstrations for organic/ biochemistry allied health courses  Deavor, James P.
Simple demonstrations on enantiomeric pairs and protein structure.
Deavor, James P. J. Chem. Educ. 1988, 65, 622.
Enantiomers |
Chirality / Optical Activity |
Proteins / Peptides |
Nonmajor Courses |
Amino Acids
Protein structure prediction in color  Davis, Lawrence C.; Radke, Gary A.
84. Implementing the Chuo and Faslar method for prediction of secondary structure and the Kyte and Doolittle method for predicting "hydropathic character" on an Apple IIe computer with color graphics.
Davis, Lawrence C.; Radke, Gary A. J. Chem. Educ. 1987, 64, 582.
Proteins / Peptides |
Molecular Properties / Structure
Use of the "cubic snake" as a molecular model  Gilon, Chaim
Using a "cubic snake" to model macromolecules.
Gilon, Chaim J. Chem. Educ. 1985, 62, 1074.
Molecular Modeling |
Molecular Properties / Structure |
Proteins / Peptides |
Enzymes
Zinc enzymes  Bertini, I.; Luchinat, C.; Monnanni, R.
The role played by catalytic and noncatalytic zinc in biochemical systems. From the "State of the Art Symposium: Bioinorganic Chemistry", held at the ACS meeting, Miami, 1985.
Bertini, I.; Luchinat, C.; Monnanni, R. J. Chem. Educ. 1985, 62, 924.
Enzymes |
Bioinorganic Chemistry |
Lewis Acids / Bases |
Proteins / Peptides
Protein denaturation: A physical chemistry project lab  Pickering, Miles; Crabtree, Robert H.
This experiment links physical chemistry with biology and can be done with in advanced freshman course.
Pickering, Miles; Crabtree, Robert H. J. Chem. Educ. 1981, 58, 513.
Proteins / Peptides |
Biophysical Chemistry |
Molecular Properties / Structure
Compact Compacts  Huebner, Jay S.; Shiflett, R. B.; Blanck, Harvey F.
A collection of three suggestions regarding demonstrating the oxidation of hydrocarbons and the primary, secondary, and tertiary structure of proteins and the first law of thermodynamics as applied to air conditioning.
Huebner, Jay S.; Shiflett, R. B.; Blanck, Harvey F. J. Chem. Educ. 1979, 56, 389.
Oxidation / Reduction |
Alkanes / Cycloalkanes |
Molecular Properties / Structure |
Proteins / Peptides |
Thermodynamics
Allied health chemistry laboratory. Amino acids, insulin, proteins, and skin  Dever, David F.
Describes an allied health chemistry laboratory involving amino acids, insulin, proteins and skin that begins with the construction of molecular models of amino acids and proteins.
Dever, David F. J. Chem. Educ. 1975, 52, 338.
Amino Acids |
Proteins / Peptides |
Medicinal Chemistry |
Nonmajor Courses |
Molecular Properties / Structure |
Molecular Modeling |
Applications of Chemistry
Photochemical reactions of natural macromolecules. Photoreactions of proteins  Neckers, Douglas C.
Reviews salient features of protein destruction by ultraviolet radiation.
Neckers, Douglas C. J. Chem. Educ. 1973, 50, 164.
Photochemistry |
Proteins / Peptides |
Amino Acids
Models for tertiary structures: Myoglobin and lysozyme  Smith, Ivor; Smith, Margaret J.; Roberts, Lynne
Presents the design details for constructing three dimensional models of proteins, including myoglobin and lysozyme.
Smith, Ivor; Smith, Margaret J.; Roberts, Lynne J. Chem. Educ. 1970, 47, 302.
Molecular Properties / Structure |
Molecular Modeling |
Proteins / Peptides |
Hydrogen Bonding |
Noncovalent Interactions