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Journal Articles: 41 results
Biochemical View: A Web Site Providing Material for Teaching Biochemistry Using Multiple Approaches  Fernanda C. Dórea, Higor S. Rodrigues, Oscar M. M. Lapouble, Márcio R. Pereira, Mariana S. Castro, and Wagner Fontes
Biochemical View is a free, full access Web site whose main goals are to complement existing biochemistry instruction and materials, provide material to teachers preparing conventional and online courses, and popularize the use of these resources in undergraduate courses.
Dórea, Fernanda C.; Rodrigues, Higor S.; Lapouble, Oscar M. M.; Pereira, Márcio R.; Castro, Mariana S.; Fontes, Wagner. J. Chem. Educ. 2007, 84, 1866.
Amino Acids |
Bioenergetics |
Carbohydrates |
Enzymes |
Glycolysis |
Lipids |
Metabolism |
Fatty Acids
Structures for the ABO(H) Blood Group: Which Textbook Is Correct?  John M. Risley
Six textbooks and two Internet sites show different structures for the A, B, and O(H) antigens of the ABO(H) blood group, but none of them are correct. This article emphasizes the correct molecular structures because it is important to distinguish between those carbohydrates that make up the antigens and those that are not part of the antigenic structures.
Risley, John M. J. Chem. Educ. 2007, 84, 1546.
Bioorganic Chemistry |
Carbohydrates |
Natural Products |
Molecular Properties / Structure
The A1c Blood Test: An Illustration of Principles from General and Organic Chemistry  Robert C. Kerber
The glycated hemoglobin blood test is a key measure of the effectiveness of glucose control in diabetics. The chemistry of glucose in the bloodstream, which underlies the test and its impact, provides an illustration of the importance of chemical equilibrium and kinetics to a major health problem.
Kerber, Robert C. . J. Chem. Educ. 2007, 84, 1541.
Applications of Chemistry |
Bioinorganic Chemistry |
Carbohydrates |
Mechanisms of Reactions |
Proteins / Peptides |
Bioorganic Chemistry
Popcorn—What's in the Bag?  Marissa B. Sherman and Thomas A. Evans
Three independent activities explore microwave popcorn, the nature of the packaging, and the popcorn produced.
Sherman, Marissa B.; Evans, Thomas A. J. Chem. Educ. 2006, 83, 416A.
Carbohydrates |
Nutrition |
Physical Properties |
Solutions / Solvents |
Water / Water Chemistry
Acetal Protecting Groups in the Organic Laboratory: Synthesis of Methyl 4,6-O-Benzylidene-α-D-Glucopyranoside  Alexei V. Demchenko, Papapida Pornsuriyasak, and Cristina De Meo
The synthesis of methyl 4,6-O-benzylidene-a-D-glucopyranoside provides an opportunity to synthesize a cyclic acetal; stereoselectively introduce a chirality center; and learn extraction, evaporation, precipitation, optical rotation, melting point measurement, thin-layer chromatography, IR-spectroscopy, mass spectrometry, and various NMR techniques.
Demchenko, Alexei V.; Pornsuriyasak, Papapida; De Meo, Cristina. J. Chem. Educ. 2006, 83, 782.
Carbohydrates |
IR Spectroscopy |
Medicinal Chemistry |
NMR Spectroscopy |
Thin Layer Chromatography |
Synthesis
The Chemistry of Popcorn: Polymers of Glucose  William F. Coleman
The Featured Molecules this month are all polymers of glucose and include cellobiose, maltose, 10-mer of cellulose, 40-mer of amylose, and an amylopectin fragment.
Coleman, William F. J. Chem. Educ. 2006, 83, 413.
Molecular Modeling |
Molecular Properties / Structure |
Carbohydrates
Glycosyltransferases A and B: Four Critical Amino Acids Determine Blood Type  Natisha L. Rose, Monica M. Palcic, and Stephen V. Evans
Human A, B, and O blood type is determined by the presence or absence of distinct carbohydrate structures on red blood cells. In this review the chemistry of the blood group ABO system and the role of glycosyltransferase A, glycosyltransferase B, and the four amino acids critical to determining blood group status are discussed.
Rose, Natisha L.; Palcic, Monica M.; Evans, Stephen V. J. Chem. Educ. 2005, 82, 1846.
Carbohydrates |
Enzymes |
Kinetics |
Bioorganic Chemistry |
Crystals / Crystallography |
Molecular Biology |
X-ray Crystallography |
Amino Acids
Essentials of Carbohydrate Chemistry and Biochemistry, 2nd Edition (Thisbe K. Lindhorst)  David J. A. Schedler
This book is aptly named: it is a well organized, well written presentation of the essentials of carbohydrate chemistry and their relationship to biochemistry.
Schedler, David J. A. J. Chem. Educ. 2004, 81, 808.
Carbohydrates
Use of Optical Rotation and NMR Signal Counting To Identify Common Aldoses  John Almy
An inexpensive, small scale experiment for second semester organic students describes the unambiguous identification of a common aldose "unknown" from five possible candidates: glucose, mannose, galactose, arabinose, or xylose
Almy, John. J. Chem. Educ. 2004, 81, 708.
NMR Spectroscopy |
Carbohydrates |
Microscale Lab |
Molecular Properties / Structure |
Stereochemistry
Tensile Strength Measurements on Biopolymer Films  Eugene S. Stevens and Mark D. Poliks
Measuring the tensile strength of biopolymer films using a simple student apparatus; results are compared with data obtained from industry-standard equipment.
Stevens, Eugene S.; Poliks, Mark D. J. Chem. Educ. 2003, 80, 810.
Biotechnology |
Carbohydrates |
Industrial Chemistry |
Laboratory Equipment / Apparatus |
Materials Science |
Proteins / Peptides
Factors Affecting Reaction Kinetics of Glucose Oxidase  Kristin A. Johnson
Demonstration based on a biochemical kinetics experiment in which the rate of reaction varies with the enzyme concentration, substrate concentration, substrate used in the reaction, and temperature.
Johnson, Kristin A. J. Chem. Educ. 2002, 79, 74.
Enzymes |
Kinetics |
Proteins / Peptides |
Carbohydrates |
Catalysis |
Rate Law
Ethanol Metabolism and the Transition from Organic Chemistry to Biochemistry  Richard D. Feinman
Introducing alcohol dehydrogenase and aldehyde dehydrogenase reactions in organic chemistry to ease transition to biochemistry.
Feinman, Richard D. J. Chem. Educ. 2001, 78, 1215.
Metabolism |
Oxidation / Reduction |
Reactions |
Mechanisms of Reactions |
Alcohols |
Carbohydrates
Correction to "Drug Metabolism: The Body's Defense against Chemical Attack" (J. Chem. Educ. 2000, 77, 349-353)  
Corrections to molecular structures.
J. Chem. Educ. 2001, 78, 312.
Carbohydrates |
Drugs / Pharmaceuticals |
Enzymes |
Medicinal Chemistry |
Metabolism |
Synthesis
The Other Double Helix--The Fascinating Chemistry of Starch  Robert D. Hancock and Bryon J. Tarbet
The chemistry of starch, particularly the structure of starch and starch granules.
Hancock, Robert D.; Tarbet, Bryon J. J. Chem. Educ. 2000, 77, 988.
Bioorganic Chemistry |
Carbohydrates |
Food Science |
Stereochemistry |
Applications of Chemistry |
Molecular Properties / Structure
Identifying Softwoods and Hardwoods by Infrared Spectroscopy  Brady Barker and Noel L. Owen
Infrared spectra of 45 softwoods and hardwoods have been recorded. The wavenumber values of the carbonyl stretching vibration and one of the ring-breathing modes of lignin are used to distinguish softwoods from hardwoods. The differences between the absorption bands for the softwoods and hardwoods in each instance are shown to be statistically significant.
Barker, Brady; Owen, Noel L. J. Chem. Educ. 1999, 76, 1706.
Carbohydrates |
Instrumental Methods |
IR Spectroscopy |
Plant Chemistry |
Molecular Properties / Structure
Demonstration of Optical Rotatory Dispersion of Sucrose  S. M. Mahurin, R. N. Compton, and Richard N. Zare
A method for demonstrating and measuring the optical activity of chiral molecules in solution is described in which the rotation of linearly polarized light is directly observed at right angles to the propagation of light in the liquid.
Mahurin, S. M.; Compton, Robert N.; Zare, Richard N. J. Chem. Educ. 1999, 76, 1234.
Instrumental Methods |
Lasers |
Spectroscopy |
Carbohydrates
A New Method To Convert the Fischer Projection of Monosaccharide to the Haworth Projection  Qing-zhi Zhang and Shen-song Zhang
The D,L-configuration of a sugar in Haworth projection can be directly determined by designating the R,S-configuration of the highest-numbered asymmetric carbon; that is, the most distant carbon from the anomeric carbon. The R-configuration at this carbon corresponds to the D-family, and S- to the L-family.
Zhang, Qing-zhi; Zhang, Shen-song. J. Chem. Educ. 1999, 76, 799.
Carbohydrates |
Stereochemistry |
Molecular Properties / Structure |
Molecular Modeling
A Very Simple Method Way to Convert Haworth Representation to Zigzag Representation  Janine Cossy and Véronique Bellosta
A very simple method to convert Haworth representation of hexoses and pentoses to zigzag representation is proposed
Cossy, Janine; Bellosta, Véronique. J. Chem. Educ. 1998, 75, 1307.
Carbohydrates |
Nomenclature / Units / Symbols |
Stereochemistry |
Molecular Properties / Structure
Protecting Groups in Carbohydrate Chemistry  Sigthór Pétursson
The most important protecting groups in carbohydrate chemistry are reviewed. The paper is aimed at those beginning to specialize in synthetic carbohydrate chemistry and at teachers with other specialties who wish to go beyond the content of general organic chemistry textbooks.
Petursson, Sigthor. J. Chem. Educ. 1997, 74, 1297.
Carbohydrates |
Molecular Properties / Structure |
Synthesis
The Blue Bottle Experiment Revisited: How Blue? How Sweet?  Cook, A. Gilbert; Tolliver, Randi M.; Williams, Janelle E.
Determining whether other colors and carbohydrates are possible with the "Blue Bottle" reaction.
Cook, A. Gilbert; Tolliver, Randi M.; Williams, Janelle E. J. Chem. Educ. 1994, 71, 160.
Aromatic Compounds |
Reactions |
Rate Law |
Mechanisms of Reactions |
Carbohydrates |
Oxidation / Reduction
An Informative Model of Haworth Structures  Rowe, H. Alan.
Exercise that gives students experience in manipulating Hawthorn structures.
Rowe, H. Alan. J. Chem. Educ. 1994, 71, 131.
Molecular Properties / Structure |
Carbohydrates
Biodegradable films: Based on partially hydrolyzed corn starch or potato starch   Sommerfeld, Herbert; Blume, Rudiger
Demonstration of the promising developments in starch chemistry can be done with short and relevant classroom experiments.
Sommerfeld, Herbert; Blume, Rudiger J. Chem. Educ. 1992, 69, A151.
Carbohydrates |
Natural Products
Inclass interactive worksheets for organic chemistry  Ostercamp, Daryl L.
The author has designed two in-class worksheets for use near the end of a two semester organic chemistry course, one dealing with mono- and disaccharides and the second dealing with alpha-amino acids and dipeptides.
Ostercamp, Daryl L. J. Chem. Educ. 1992, 69, 318.
Carbohydrates |
Amino Acids |
Proteins / Peptides
NMR and the structure of D-glucose  Gurst, Jerome E.
A discussion of typical organic chemistry textbook treatment of NMR evidence of glucose structure.
Gurst, Jerome E. J. Chem. Educ. 1991, 68, 1003.
Carbohydrates |
NMR Spectroscopy
Binary representation in carbohydrate nomenclature  McGinn, Clifford J.; Wheatley, William B.
A binary notation is used to indicate the structure of carbohydrates.
McGinn, Clifford J.; Wheatley, William B. J. Chem. Educ. 1990, 67, 747.
Carbohydrates |
Nomenclature / Units / Symbols |
Stereochemistry
Using an oval to represent carbohydrates with hexopyranose rings  Fulkrod, John E.
An shorthand alternative to representing hexopyranose rings using chair conformation structures.
Fulkrod, John E. J. Chem. Educ. 1989, 66, 485.
Carbohydrates |
Molecular Properties / Structure
Carbohydrate stereochemistry  Shallenberger, Robert S.; Wienen, Wanda J.
A progress in the development of general stereochemical principles has been significantly influenced by studies that led to determination of the crystalline and solution structures of sugars, the subject of carbohydrate chemistry is developed here in historical fashion.
Shallenberger, Robert S.; Wienen, Wanda J. J. Chem. Educ. 1989, 66, 67.
Carbohydrates |
Stereochemistry
A laboratory exercise in the determination of carbohydrate structures  White, Bernard J.; Robyt, John F.
A laboratory exercise in the determination of carbohydrate structures that introduces students to important aspects of science, such as designing experiments, making observations, and testing hypotheses.
White, Bernard J.; Robyt, John F. J. Chem. Educ. 1988, 65, 164.
Carbohydrates
Configurations of glucose and other aldoses: New twists and reflections an old problems  Bentley, Ronald; Popp, Janet L.
Develops a comprehensive treatment of the configurations of aldoses in terms of the concept of rotational symmetry.
Bentley, Ronald; Popp, Janet L. J. Chem. Educ. 1987, 64, 15.
Carbohydrates |
Stereochemistry |
Molecular Properties / Structure
Simple rule for the conversion of Fischer monosaccharide projection formulas into Haworth representations  Argiles, J. M.
Many students struggle with memorizing Haworth structures, the authors provide some insight on this topic to help students.
Argiles, J. M. J. Chem. Educ. 1986, 63, 927.
Molecular Properties / Structure |
Enantiomers |
Chirality / Optical Activity |
Carbohydrates |
Molecular Modeling
Total Synthesis of Natural Products: The 'Chiron' Approach (Hanessian, Stephen)  Wade, Leroy G., Jr.
Details the use of carbohydrate derivatives as chiral starting points for the synthesis of chiral products.
Wade, Leroy G., Jr. J. Chem. Educ. 1985, 62, A190.
Natural Products |
Synthesis |
Carbohydrates |
Chirality / Optical Activity
[Brand] rand the name with the linkage of the same  Garrett, James M.
Tool for helping to remember the configuration of the glucosidic linkages in maltose and cellobiose.
Garrett, James M. J. Chem. Educ. 1984, 61, 665.
Carbohydrates |
Molecular Properties / Structure
Cycloamyloses  Bergeron, Raymond J.
Examines an unusual carbohydrate system of current interest in the hope of generating some enthusiasm for the topic.
Bergeron, Raymond J. J. Chem. Educ. 1977, 54, 204.
Carbohydrates |
Molecular Properties / Structure |
Thermodynamics |
Kinetics |
Enzymes |
Spectroscopy
a[alpha]- and [bet]a-D-glucose pentaacetate. An experiment in structure assignment using NMR  Pearson, Wesley A.; Spessard, Gary O.
The synthesis and structural determination of alpha- and beta-D-glucose pentaacetate.
Pearson, Wesley A.; Spessard, Gary O. J. Chem. Educ. 1975, 52, 814.
NMR Spectroscopy |
Carbohydrates |
Synthesis
A simplified proof of the constitution and configuration of D-glucose  Frohwein, Y, Z.
Presents a simplified proof of the constitution and configuration of D-glucose for students being introduced to carbohydrate chemistry.
Frohwein, Y, Z. J. Chem. Educ. 1969, 46, 55.
Carbohydrates |
Molecular Properties / Structure |
Enantiomers |
Chirality / Optical Activity
Letter to the editor  Bhatnagar, Vijay Mohan
Distinguishes between alpha- and beta-amylose and their mixtures, particular with respect to iodimetric titrations.
Bhatnagar, Vijay Mohan J. Chem. Educ. 1967, 44, 771.
Titration / Volumetric Analysis |
Carbohydrates
Polyethylene and pipecleaner models of biological polymers  Pollard, Harvey Bruce
An accurate method for modeling polysaccharides, nucleic acids, and proteins involves the use of pipecleaners, polyethylene tubing, and proteins.
Pollard, Harvey Bruce J. Chem. Educ. 1966, 43, 327.
Proteins / Peptides |
Molecular Modeling |
Molecular Properties / Structure |
Carbohydrates
A panoramic approach to the proof of configuration of aldohexoses  Rosenblatt, David H.
Presents a didactic approach to the classical proofs of configuration of aldohexoses.
Rosenblatt, David H. J. Chem. Educ. 1965, 42, 271.
Molecular Properties / Structure |
Carbohydrates
Effect of liquid NH3 on wood: A demonstration of the alcohol structure of cellulose  Hirsch, Phillis R.
A lecture demonstration of the plasticization of wood with liquid ammonia can be a very effective tool for teaching the alcohol structure of cellulose to any class studying basic organic chemistry.
Hirsch, Phillis R. J. Chem. Educ. 1964, 41, 605.
Carbohydrates |
Alcohols |
Molecular Properties / Structure
The geometry of giant molecules  Price, Charles C.
The author examines a variety of specific examples of natural and synthetic polymer molecules and describes how their geometric molecular arrangements influence their properties.
Price, Charles C. J. Chem. Educ. 1959, 36, 160.
Molecular Properties / Structure |
Proteins / Peptides |
Carbohydrates
Schematic models of biochemical polymers  Blackwell, R. Quentin
Demonstrates the use of plastic necklace beads to represent polysaccharides, peptides and proteins, and nucleotides.
Blackwell, R. Quentin J. Chem. Educ. 1957, 34, 500.
Molecular Modeling |
Molecular Properties / Structure |
Proteins / Peptides |
Carbohydrates