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Journal Articles: 42 results
"As Simple as Possible, but Not Simpler"—The Case of Dehydroascorbic Acid  Robert C. Kerber
Textbooks routinely assign dehydroascorbic acid a tricarbonyl structure that is highly improbable in aqueous solution and inconsistent with its colorless appearance. Studies of oxidized forms of ascorbic acid are summarized here, and a plea is entered for accurate descriptions of chemical structures in this and other cases, even at the cost of some simplicity.
Kerber, Robert C. J. Chem. Educ. 2008, 85, 1237.
Bioorganic Chemistry |
Free Radicals |
Natural Products |
NMR Spectroscopy |
Vitamins
The Role of Water Chemistry in Marine Aquarium Design: A Model System for a General Chemistry Class  Jeffrey J. Keaffaber, Ramiro Palma, and Kathryn R. Williams
Water chemistry is central to aquarium design, and it provides many potential applications for discussion in undergraduate chemistry and engineering courses. This article uses a hypothetical tank to house ocean sunfish as a model to show students the calculations and other considerations that are needed when designing a marine aquarium.
Keaffaber, Jeffrey J.; Palma, Ramiro; Williams, Kathryn R. J. Chem. Educ. 2008, 85, 225.
Acids / Bases |
Aqueous Solution Chemistry |
Consumer Chemistry |
Oxidation / Reduction |
Stoichiometry |
Water / Water Chemistry
Chemical Aspects of General Anesthesia: Part II. Current Practices  Robert Brunsvold and Daryl L. Ostercamp
With the basic elements of balanced general anesthesia in place by the 1950s, the focus turned to developing safer and more effective agents and to improving procedures. During the last half-century a new generation of intravenous induction anesthetics, inhalational anesthetics, and muscle relaxants has emerged.
Brunsvold, Robert; Ostercamp, Daryl L. J. Chem. Educ. 2006, 83, 1826.
Bioorganic Chemistry |
Chirality / Optical Activity |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Synthesis
Chemical Aspects of General Anesthesia: Part I. From Ether to Halothane  Robert Brunsvold and Daryl L. Ostercamp
Summarizes general anesthesia from 1846 to 1956. Events leading up to the adoption of a "balanced" approach, where a sequence of individual compounds is used rather than a single agent, are described.
Brunsvold, Robert; Ostercamp, Daryl L. J. Chem. Educ. 2006, 83, 1821.
Acids / Bases |
Bioorganic Chemistry |
Chirality / Optical Activity |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Synthesis
Chemical Aspects of Local and Regional Anesthesia  Robert Brunsvold and Daryl L. Ostercamp
The chemistry that underlies the development of local and regional anesthesia is explored. Emphasis is placed upon the importance of acidity constants and lipophilic versus hydrophilic character in interpreting what affect a particular compound has upon biological processes.
Brunsvold, Robert; Ostercamp, Daryl L. J. Chem. Educ. 2006, 83, 1816.
Acids / Bases |
Bioorganic Chemistry |
Chirality / Optical Activity |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Synthesis |
Applications of Chemistry
Assaying α-Dicarbonyl Compounds in Wine: A Complementary GC–MS, HPLC, and Visible Spectrophotometric Analysis  Tammy J. Dwyer and Jeremiah D. Fillo
A facile, aqueous reaction coupled with gas chromatographymass spectrometry, visible spectrophotometry, and high performance liquid chromatography is used to quantify the amounts of a-dicarbonyl compounds in wine samples.
Dwyer, Tammy J.; Fillo, Jeremiah D. J. Chem. Educ. 2006, 83, 273.
Aromatic Compounds |
Chromatography |
Food Science |
HPLC |
Mass Spectrometry |
Quantitative Analysis |
Synthesis |
UV-Vis Spectroscopy
Biochemistry: The Chemical Reactions of Living Cells, 2nd Edition (David E. Metzler)  Arthur Glasfeld
The material in this text is never too advanced for a junior chemistry or biochemistry major; it makes no demands beyond the readers comfort with general and organic chemistry.
Glasfeld, Arthur. J. Chem. Educ. 2004, 81, 646.
Novel Strategies for the Removal of Toxic Metals from Soils and Waters  D. Max Roundhill
This article surveys the toxicities of mercury, cadmium, lead, copper, cadmium, and the actinides. Strategies for the removal of these metals include surfactants, aqueous biphasic systems, and liquid membranes. For soils, both in situ stabilization and detection are discussed.
Roundhill, D. Max. J. Chem. Educ. 2004, 81, 275.
Green Chemistry |
Separation Science |
Water / Water Chemistry |
Metals |
Toxicology
Ethanol Metabolism and the Transition from Organic Chemistry to Biochemistry  Richard D. Feinman
Introducing alcohol dehydrogenase and aldehyde dehydrogenase reactions in organic chemistry to ease transition to biochemistry.
Feinman, Richard D. J. Chem. Educ. 2001, 78, 1215.
Metabolism |
Oxidation / Reduction |
Reactions |
Mechanisms of Reactions |
Alcohols |
Carbohydrates
The Isothermal Heat Conduction Calorimeter: A Versatile Instrument for Studying Processes in Physics, Chemistry, and Biology  Lars Wadsö, Allan L. Smith, Hamid Shirazi, S. Rose Mulligan, and Thomas Hofelich
A simple but sensitive isothermal heat-conduction calorimeter and five experiments for students to illustrate its use (heat capacity of solids, acid-base titration, enthalpy of vaporization of solvents, cement hydration, and insect metabolism).
Wadsö, Lars; Smith, Allan L.; Shirazi, Hamid; Mulligan, S. Rose; Hofelich, Thomas. J. Chem. Educ. 2001, 78, 1080.
Calorimetry / Thermochemistry |
Laboratory Equipment / Apparatus |
Thermal Analysis |
Thermodynamics
A PDR Problem for Sophomore Organic Students  Rosa Betancourt
This article contains a series of questions that guide a short investigation of the chemistry of nonsteroidal antiinflammatory drugs.
Betancourt-Perez, Rosa. J. Chem. Educ. 1999, 76, 1101.
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Solutions / Solvents |
Applications of Chemistry
Kinetics of p-Nitrophenol Degradation by Pseudomonas sp.: An Experiment Illustrating Bioremediation  Michelle H. Duong, Samuel L. Penrod, and Stanley B. Grant
This paper describes a simple experiment illustrating bioremediation which is well suited for undergraduate classes in environmental chemistry, microbiology, or engineering.
Duong, Michelle H.; Penrod, Samuel L.; Grant, Stanley B. J. Chem. Educ. 1997, 74, 1451.
Biotechnology |
Kinetics |
Oxidation / Reduction |
Applications of Chemistry
Global Metabolism of Elements: Principles and Applications in Bioinorganic Chemistry - XI  Ei-Ichiro Ochiai
The biosphere, as its members metabolize the elements, can thus contribute to the overall global geocycling of elements. A diagram is used to indicate several different manners of the contribution and their extents of contribution to the geoprocesses. This overall process incorporating the effects of the biosphere is termed here as "global metabolism" and is illustrated for iron, mercury and arsenic.
Ochiai, Ei-Ichiro. J. Chem. Educ. 1997, 74, 926.
Bioinorganic Chemistry |
Geochemistry
The Manifestation of Evolutionary Pressure in Bioinorganic Chemistry: Principles and Applications in Bioinorganic Chemistry - IX  Ei-Ichiro Ochiai
We know virtually nothing about the evolutionary processes themselves that led to invention of the biocompounds found in the earlier organisms. What we know of is the biomolecules in the organisms presently existing on earth. The only thing we can do then is to rationalize why a biomolecule found in contemporary organisms takes a specific structure and why it behaves the way it does.
Ochiai, Ei-Chiro. J. Chem. Educ. 1997, 74, 348.
Bioinorganic Chemistry
The conversion of chemical energy: Part 2. Biochemical examples  Wink, Donald J.
Biological systems regulate energy transfer reactions through enzymes that permit a spontaneous reaction to go faster through a mechanism that also accomplishes work instead of, or in addition to, releasing energy as heat.
Wink, Donald J. J. Chem. Educ. 1992, 69, 264.
Enzymes |
Bioorganic Chemistry |
Bioenergetics
Microscale Organic Laboratory, Second Edition (Mayo, Dana W.)  Wade, Leroy G., Jr.
For instructors who prefer the microscale approach, this Second Edition demands serious consideration.
Wade, Leroy G., Jr. J. Chem. Educ. 1990, 67, A29.
Microscale Lab
Biochemistry, Third Edition (Armstrong, Frank B.)  Fried, Melvin
The purpose of the text is to provide a basis for a general introductory course for undergraduates in such curricula as preprofessional programs, biological and agricultural sciences, chemistry, engineering, and science education.
Fried, Melvin J. Chem. Educ. 1990, 67, A28.
Fundamentals of Chemistry: General, Organic, Biological (Deleo, Joseph D.)  Wolsey, Wayne C.
This text is a new entry into the very competitive market of chemistry for the allied health sciences.
Wolsey, Wayne C. J. Chem. Educ. 1989, 66, A45.
Nonmajor Courses
Decarboxylation of a keto acids  Hanson, R. W.
Rectifies the lack of information concerning the nonenzymatic decarboxylation of alpha-keto acids found in many textbooks and to correct errors found in others.
Hanson, R. W. J. Chem. Educ. 1987, 64, 591.
Mechanisms of Reactions |
Catalysis
The metabolism of xenobiotic chemicals  Cullen, John W.
Metabolic processes can produce compounds that are more toxic than that originally inhaled or ingested; considers Phase I and Phase II reactions and their major constituents.
Cullen, John W. J. Chem. Educ. 1987, 64, 396.
Metabolism |
Toxicology |
Enzymes |
Drugs / Pharmaceuticals
Metabolic questions  Akers, Hugh A.
Students are asked to construct a metabolic pathway from a description of a sequence of events and to identify (logical) cofactors that are anticipated to be utilized.
Akers, Hugh A. J. Chem. Educ. 1987, 64, 159.
Metabolism |
Enzymes
Name that compound, Part II  Mancott, A.
This problem requires the sue of algebraic reasoning to derive and solve a dophantine equation whose parameters are restricted to being integers.
Mancott, A. J. Chem. Educ. 1987, 64, 159.
Chemometrics
Energy interconversions in photosynthesis  Bering, Charles L.
Reviews the energetics of the light reactions of photosynthesis.
Bering, Charles L. J. Chem. Educ. 1985, 62, 659.
Photosynthesis |
Photochemistry |
Thermodynamics |
Bioenergetics
Drug stabilization against oxidative degradation  Akers, Michael J.
Describes the process of oxidation and ways in which pharmaceutical preparations can be protected from oxidative degredation.
Akers, Michael J. J. Chem. Educ. 1985, 62, 325.
Drugs / Pharmaceuticals |
Oxidation / Reduction |
Medicinal Chemistry |
Nonmajor Courses
Methemoglobinemia: An illness caused by the ferric state  Senozan, N. M.
Hemoglobin's ability to carry oxygen depends on the iron being in the +2 state; methemoglobinemia involves the oxidation of hemoglobin iron to the +3 state.
Senozan, N. M. J. Chem. Educ. 1985, 62, 181.
Proteins / Peptides |
Enzymes |
Medicinal Chemistry |
Oxidation / Reduction |
Oxidation State
Biochemistry for nutrition/dietetics students: Course content  Sirota, Lorraine Handler
Results regarding surveys of biochemistry resources and content for nutrition/dietetics students.
Sirota, Lorraine Handler J. Chem. Educ. 1984, 61, 430.
Nutrition |
Medicinal Chemistry |
Nonmajor Courses
Isoenzymes  Daugherty, N. A.
The separation, identification, and measurement of isoenzymes is an appropriate topic for a special lecture in general chemistry.
Daugherty, N. A. J. Chem. Educ. 1979, 56, 442.
Enzymes |
Proteins / Peptides |
pH |
Electrophoresis |
Separation Science |
Electrochemistry |
Applications of Chemistry
Chemical toxicology. Part I. Organic compounds  Carter, D. E.; Fernando, Quintus
General principles of toxicology, and particular consideration of aliphatics, aromatic, and halogenated hydrocarbons; alcohols, aldehydes, esters, ethers, and ketones; sulfides, mercaptans, and carbon disulfide; nitrogen-containing compounds; and carcinogens.
Carter, D. E.; Fernando, Quintus J. Chem. Educ. 1979, 56, 284.
Toxicology |
Alcohols |
Aldehydes / Ketones |
Esters |
Ethers |
Aromatic Compounds |
Amines / Ammonium Compounds |
Lipids
Some aspects of the bioinorganic chemistry of molybdenum  Swedo, Kathleen Bizot; Enemark, John H.
The biological role of molybdenum, biophysical studies of the molybdenum atoms in molybdo-enzymes, and aspects of coordination chemistry that bear on the understanding of molybdo-enzymes.
Swedo, Kathleen Bizot; Enemark, John H. J. Chem. Educ. 1979, 56, 70.
Bioinorganic Chemistry |
Organometallics |
Enzymes |
Coordination Compounds |
Transition Elements
Teaching bio-organometal chemistry. II. The metals  Thayer, John S.
Considers the toxicology and environmental cycles of compounds containing mercury, germanium, tin, lead, antimony, bismuth, cobalt, and other metals.
Thayer, John S. J. Chem. Educ. 1977, 54, 662.
Organometallics |
Bioinorganic Chemistry |
Toxicology
Electrochemistry in organisms. Electron flow and power output  Chirpich, Thomas P.
Electrochemical calculations at an elementary level can be readily applied to living organisms and generate further student interest in electrochemistry.
Chirpich, Thomas P. J. Chem. Educ. 1975, 52, 99.
Electrochemistry |
Bioenergetics
Sulfur compounds. Pollution, health effects, and biological function  Leh, F.; Chan, K. M.
Reviews the role of sulfur and its compounds in pollution and adverse health effects as well as biological functions.
Leh, F.; Chan, K. M. J. Chem. Educ. 1973, 50, 246.
Nonmetals |
Proteins / Peptides
ATP synthesis: The current controversy  Deamer, David W.
The mechanisms by which ATP is utilized in the important processes of muscle contraction and ion transport are not at all clear; the controversy over the mechanism of phosphorylation offers insight into the style of modern biochemical research.
Deamer, David W. J. Chem. Educ. 1969, 46, 198.
Bioenergetics
Introduction to organic chemistry (DePuy, Charles H.; Rinehart, Kenneth L., Jr.)  Naff, M. Benton

Naff, M. Benton J. Chem. Educ. 1968, 45, 148.
Biological oxidations and energy conservation  Kirschbaum, Joel
Examines the oxidative steps leading to the synthesis of ATP in living organisms and their metabolic control.
Kirschbaum, Joel J. Chem. Educ. 1968, 45, 28.
Bioenergetics |
Oxidation / Reduction |
Thermodynamics |
Metabolism
Mode of action of toxic substances  Stokinger, Herbert E.
Examines the mechanisms of toxic substances.
Stokinger, Herbert E. J. Chem. Educ. 1967, 44, A885.
Toxicology |
Laboratory Management
Recent developments in calorimetry. Part 3. Some specific types of calorimeters (conclusion)  Wilhoit, Randolph C.
Examines the topics of solution calorimetry, microcalorimetry, dynamic calorimetry, and the instrumentation used to conduct these analyses.
Wilhoit, Randolph C. J. Chem. Educ. 1967, 44, A853.
Calorimetry / Thermochemistry |
Instrumental Methods |
Laboratory Equipment / Apparatus
The history of the Warburg apparatus: Some reminiscences on its use  Oesper, Peter
The Warburg apparatus is a device for measuring the pressure of a gas at constant volume and constant temperature so that the pressure is a measure of the quantity of gas and changes in pressure reflect the production or absorption of gas.
Oesper, Peter J. Chem. Educ. 1964, 41, 294.
Laboratory Equipment / Apparatus |
Gases
Chemical bonding and the geometry of molecules (Ryschkewitsch, George E.)  Eblin, Lawrence P.

Eblin, Lawrence P. J. Chem. Educ. 1963, 40, 441.
Molecular Properties / Structure |
Covalent Bonding
Experiments in general, organic, and biological chemistry: A laboratory manual (Holum, John R.)  Horton, Derek

Horton, Derek J. Chem. Educ. 1963, 40, 441.
Chem sources   Kieffer, William F.

Kieffer, William F. J. Chem. Educ. 1963, 40, 172.
Laboratory Management
Zirconium chemistry in industry  Blumenthal, Warren B.
Examines the processing of zircon; zirconium carbide, chlorides, fluorides, and sulfates; hydrous zirconia; zirconyl acetate; ammonium zirconyl carbonate; zirconium in organic chemistry; and zirconium compounds as catalysts.
Blumenthal, Warren B. J. Chem. Educ. 1962, 39, 604.
Industrial Chemistry |
Catalysis