TIGER

Journal Articles: 8 results
Using Physical Models of Biomolecular Structures To Teach Concepts of Biochemical Structure and Structure Depiction in the Introductory Chemistry Laboratory  Gordon A. Bain, John Yi, Mithra Beikmohamadi, Timothy M. Herman, and Michael A. Patrick
Custom-made physical models of alpha-helices and beta-sheets, the zinc finger moiety, beta-globin, and green fluorescent protein are used to introduce students in first-year chemistry to the primary, secondary, and tertiary structure of proteins.
Bain, Gordon A.; Yi, John; Beikmohamadi, Mithra; Herman, Timothy M.; Patrick, Michael A. J. Chem. Educ. 2006, 83, 1322.
Amino Acids |
Proteins / Peptides |
Molecular Modeling |
Molecular Properties / Structure |
Nucleic Acids / DNA / RNA
DNA Profiling of the D1S80 Locus: A Forensic Analysis for the Undergraduate Biochemistry Laboratory  D. Dewaine Jackson, Chad S. Abbey, and Dylan Nugent
Describes a laboratory exercise in DNA profiling that can be used to demonstrate four fundamental procedures: isolation of genomic DNA from human cells, use of the polymerase chain reaction to amplify DNA, separation of amplified DNAs on agarose and polyacrylamide gels, and quantitative analysis of data (while comparing two different gel separation techniques).
Jackson, D. Dewaine; Abbey, Chad S.; Nugent, Dylan. J. Chem. Educ. 2006, 83, 774.
Biological Cells |
Biotechnology |
Electrophoresis |
Forensic Chemistry |
Molecular Biology |
Quantitative Analysis |
Nucleic Acids / DNA / RNA
Glycosyltransferases A and B: Four Critical Amino Acids Determine Blood Type  Natisha L. Rose, Monica M. Palcic, and Stephen V. Evans
Human A, B, and O blood type is determined by the presence or absence of distinct carbohydrate structures on red blood cells. In this review the chemistry of the blood group ABO system and the role of glycosyltransferase A, glycosyltransferase B, and the four amino acids critical to determining blood group status are discussed.
Rose, Natisha L.; Palcic, Monica M.; Evans, Stephen V. J. Chem. Educ. 2005, 82, 1846.
Carbohydrates |
Enzymes |
Kinetics |
Bioorganic Chemistry |
Crystals / Crystallography |
Molecular Biology |
X-ray Crystallography |
Amino Acids
Identification of Forensic Samples via Mitochondrial DNA in the Undergraduate Biochemistry Laboratory  Julie T. Millard and André M. Pilon
Identification of forensic samples via mitochondrial DNA in a hypothetical kidnapping case.
Millard, Julie T.; Pilon, André M. J. Chem. Educ. 2003, 80, 444.
Quantitative Analysis |
Electrophoresis |
Separation Science |
Biotechnology |
Forensic Chemistry |
Applications of Chemistry |
Nucleic Acids / DNA / RNA
Genomics: The Science and Technology Behind the Human Genome Project (by Charles R. Cantor and Cassandra L. Smith)  reviewed by Martin J. Serra
This book is an outgrowth of a series of lectures given by one of the former heads (CRC) of the Human Genome Initiative. The book is designed to reach a wide audience, from biologists with little chemical or physical science background through engineers, computer scientists, and physicists with little current exposure to the chemical or biological principles of genetics.
Serra, Martin J. J. Chem. Educ. 2000, 77, 33.
Biotechnology |
Nucleic Acids / DNA / RNA
Chromatin Isolation and DNA Sequence Analysis in Large Undergraduate Laboratory Sections  Ann E. Hagerman
One exercise is a simple laboratory experiment in which chromatin is isolated from chicken liver and is resolved into histone proteins and DNA by ion-exchange chromatography. The other is a series of computer simulations that introduce DNA sequencing, mapping, and sequence analysis to the students.
Hagerman, Ann E. J. Chem. Educ. 1999, 76, 1426.
Biotechnology |
Proteins / Peptides |
Nucleic Acids / DNA / RNA
An Attack on the AIDS Virus: Inhibition of the HIV-1 Protease. New Drug Development Based on the Structure and Activity of the Protease and its Role in the Replication and Maturation of the Virus  Volker, Eugene J.
Article shows how research into the biochemistry of HIV may lead to a method for controlling its growth and maturation. This research illustrates some basic enzyme chemistry and holds student appeal due to the tie into current affairs.
Volker, Eugene J. J. Chem. Educ. 1993, 70, 3.
Bioorganic Chemistry |
Proteins / Peptides |
Medicinal Chemistry |
Molecular Biology
Recombinant DNA technology: A topics course for undergraduates  Parson, Kathleen A.
This article describes the development of a topics course offered jointly through chemistry and biology departments called 'Recombinant DNA, A Short Course' that uses primary literature and explores economic, political, and ethical issues of genetic engineering.
Parson, Kathleen A. J. Chem. Educ. 1988, 65, 325.
Molecular Biology |
Applications of Chemistry