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For the textbook, chapter, and section you specified we found
3 Videos
3 Assessment Questions
2 Molecular Structures
12 Journal Articles
7 Other Resources
Videos: 3 results
Factors Affecting Glucose Oxidase Activity  
Various factors which affect glucose oxidase activity are demonstrated.
Catalysis |
Enzymes |
Kinetics |
Proteins / Peptides
Halting the Briggs-Rauscher Oscillating Reaction  
The Briggs-Rauscher reaction is demonstrated in three different ways. Catalase from a liver extract decomposes the hydrogen peroxide in an Briggs-Rauscher reaction, stopping the oscillations.
Catalysis |
Kinetics |
Enzymes |
Proteins / Peptides
HIV-1 Protease: An Enzyme at Work  
This is "HIV-1 Protease: An Enzyme at Work", from a video tape published by the Journal of Chemical Education - Software as Special Issue 13
Applications of Chemistry |
Enzymes |
Proteins / Peptides |
Medicinal Chemistry
Assessment Questions: 3 results
Biochemistry : EnzymesCan (12 Variations)
Which of the following is something that enzymes CANNOT do?
Enzymes
Biochemistry : Inhibitor (15 Variations)
Which of the following molecules would you expect to be the strongest competitive inhibitor of the enzyme whose substrate is shown?

alcohol dehydrogenase, substrate ethanol
CH2CH2OH


Enzymes
Kinetics : Enzyme (7 Variations)
Trypsin assists in digestion by breaking proteins down into smaller peptides. However, this process is not as efficient in the presence of fluorophosphates. Identify the role of each of these components.
Enzymes |
Kinetics
Molecular Structures: 2 results
D-amphetamine C9H13N

3D Structure

Link to PubChem

Amines / Ammonium Compounds |
Drugs / Pharmaceuticals |
Aromatic Compounds |
Acids / Bases

diazepam C16H13ClN2O

3D Structure

Link to PubChem

Heterocycles |
Drugs / Pharmaceuticals |
Amides |
Aromatic Compounds |
Acids / Bases

Journal Articles: First 3 results.
Pedagogies:
Molecules and Medicine (E. J. Corey, Barbara Czakó, and László Kürti)  Robert E. Buntrock
Looking for a book on common drugs and pharmaceuticals? On diseases and medical conditions? On pharmacology? In addition, do you need some background in chemistry to handle all of this information? If you want all of this, and in addition want it under one cover, then this is the book for you.
Buntrock, Robert E. J. Chem. Educ. 2008, 85, 1495.
Bioorganic Chemistry |
Drugs / Pharmaceuticals |
Molecular Properties / Structure |
Proteins / Peptides |
Synthesis |
Toxicology
Mentoring an Undergraduate Research Student in the Structural and Nonstructural Properties of Drugs  Julie B. Ealy and Veronica Kvarta
This article describes research, conducted with an undergraduate, to investigate the structural and nonstructural characteristics of drugs and their significance in drug research.
Ealy, Julie B.; Kvarta, Veronica. J. Chem. Educ. 2006, 83, 1779.
Applications of Chemistry |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Molecular Modeling |
Molecular Properties / Structure |
Undergraduate Research |
Student-Centered Learning
Nature's Way To Make the Lantibiotics  Heather A. Relyea and Wilfred A. van der Donk
This article focuses on one class of antimicrobial compounds, the lantibiotics, and discusses their biosynthetic pathways as well as their molecular mode of action. In the course of the review, the meaning of the terms regio-, chemo-, and stereoselectivity are discussed.
Relyea, Heather A.; van der Donk, Wilfred A. J. Chem. Educ. 2006, 83, 1769.
Applications of Chemistry |
Bioorganic Chemistry |
Biotechnology |
Biosynthesis |
Catalysis |
Drugs / Pharmaceuticals |
Proteins / Peptides
View all 12 articles
Other Resources: First 3 results
Molecular Models of Real and Mock Illicit Drugs from a Forensic Chemistry Activity  William F. Coleman
The Featured Molecules for this month come from the paper by Shawn Hasan, Deborah Bromfield-Lee, Maria T. Oliver-Hoyo, and Jose A. Cintron-Maldonado (1). The authors describe a forensic chemistry exercise in which model compounds are used to simulate the behavior of various drugs in a series of chemical tests. Structures of a number of the chemicals used in the experiment, and several of the drugs they are serving as proxy for, have been added to the molecule collection. Other substances used in the experiment are already part of the collection, including caffeine and aspirin. One structure that may be both intriguing and confusing to students is that of chlorpromazine (Thorazine, Figure 1). A majority of students might well expect the ring portion of the molecule to show a planar structure. This is not what is found from calculations at the HF/6311++G(d,p) level in both the gas phase and in water. Instead, the three rings are in a V-like formation with a deformation of approximately 50 degrees from planarity. Tracking down the source of this non-planarity would be a useful computational exercise. Does it arise from the presence of the alkyl chain (steric effect), from the chloro group (electronic effect), or from electronic effects involving the elements of the heterocyclic ring? As a starting point to addressing these questions, students could be introduced to the use of model compounds in computation. One such compound would be the parent ring system phenothiazine (Figure 2). That molecule contains neither a chloro substituent nor an extended alkyl group. Is it also found to be non-planar? Is the deformation angle the same, larger, or smaller than in chlorpromazine? Does the addition of chloro group to phenothiazene change the angle significantly? What about the addition of an alkyl group? If the model compound is forced to be planar are all of the vibrational frequencies real (positive)? If not, what type of deformation is suggested by the imaginary (negative) vibration?
Drugs / Pharmaceuticals |
Forensic Chemistry
Enzyme Activity as a Function of pH  Paul Krause
A matched pair of documents providing an introduction to the role of pH in the regulation of enzyme activity. The tutorial document contains all the equations and graphs for students to use to study the role of pH in enzyme kinetics. In the EnzymeExercise twin document all quations are omitted so that students can develop these interactively. The Exercise document is also ideal for display during lecture where the ideas can be developed interactively with the class as a whole.
Enzymes
Catalysis in Biology  Tim Wendorff
A section of ChemPrime, the Chemical Educations Digital Library's free General Chemistry textbook.
Catalysis |
Enzymes
View all 7 results