TIGER

Journal Articles: 148 results
Real-World Topics: Medicinal Chemistry  Arrietta Clauss
Instructors often look for real-world topics that interest students when designing labs and preparing lectures. The chemistry associated with drugs is a fertile area, and the archives of the Journal can be a resource for interesting drug-related activities to enhance student learning.
Clauss, Arrietta. J. Chem. Educ. 2008, 85, 1657.
Enrichment / Review Materials |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Applications of Chemistry
Illustrating the Concepts of Isotopes and Mass Spectrometry in Introductory Courses: A MALDI-TOF Mass Spectrometry Laboratory Experiment  Nancy Carter Dopke and Timothy Neal Lovett
This article describes a matrix-assisted laser desorption/ionization (MALDI) mass spectrometry experiment in which students prepare peptide samples for mass analysis and then collect and analyze mass spectral data. The lab provides hands-on experience with research instrumentation and reinforces the concepts of isotopes, molecular masses, and molecular formulas.
Dopke, Nancy Carter; Lovett, Timothy Neal. J. Chem. Educ. 2007, 84, 1968.
Isotopes |
Mass Spectrometry |
Proteins / Peptides
Receptor Surface Models in the Classroom: Introducing Molecular Modeling to Students in a 3-D World  Werner J. Geldenhuys, Michael Hayes, Cornelis J. Van der Schyf, David D. Allen, and Sarel F. Malan
Proposes a novel method for teaching drug interactions with a receptor, enzyme, or any other macromolecule or protein using plastic molecular models and aluminum foil.
Geldenhuys, Werner J.; Hayes, Michael; Van der Schyf, Cornelis J.; Allen, David D.; Malan, Sarel F. J. Chem. Educ. 2007, 84, 979.
Bioorganic Chemistry |
Drugs / Pharmaceuticals |
Laboratory Computing / Interfacing |
Medicinal Chemistry |
Molecular Modeling |
Enzymes
Understanding Isotopic Distributions in Mass Spectrometry  Juris Meija
Offers a simple graphical tool for obtaining complex isotopic distributions.
Meija, Juris. J. Chem. Educ. 2006, 83, 1761.
Mass Spectrometry |
Isotopes |
Chemometrics
Complexometric Titration of Aluminum and Magnesium Ions in Commercial Antacids. An Experiment for General and Analytical Chemistry Laboratories  Shui-Ping Yang and Ruei-Ying Tsai
A novel experiment for determining the total and individual aluminum and magnesium ion content in commercial antacids is described. This experiment is developed with three independent protocols based on complexometric direct and back titrations containing the concepts and usages of blocking, masking, buffer controls and metallic indicators.
Yang, Shui-Ping; Tsai, Ruei-Ying. J. Chem. Educ. 2006, 83, 906.
Aqueous Solution Chemistry |
Chemometrics |
Consumer Chemistry |
Medicinal Chemistry |
Quantitative Analysis |
Titration / Volumetric Analysis |
UV-Vis Spectroscopy
The Discovery and Development of Cisplatin  Rebecca A. Alderden, Matthew D. Hall, and Trevor W. Hambley
Cisplatin is currently one of the most widely used anticancer drugs in the world. The unlikely events surrounding the discovery of its anticancer activity, subsequent introduction into the clinic, and the continuing research into platinum compounds is the subject of this review.
Alderden, Rebecca A.; Hall, Matthew D.; Hambley, Trevor W. J. Chem. Educ. 2006, 83, 728.
Bioinorganic Chemistry |
Coordination Compounds |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Metallic Bonding |
Oxidation State |
Synthesis
Calcium Phosphates and Human Beings  Sergey V. Dorozhkin
This article describes the general importance of calcium phosphates for human beings. The basic information on the structure and chemical properties of the biologically relevant calcium phosphates is summarized.
Dorozhkin, Sergey V. J. Chem. Educ. 2006, 83, 713.
Applications of Chemistry |
Bioinorganic Chemistry |
Biotechnology |
Materials Science |
Medicinal Chemistry |
Natural Products
The History of Element 43—Technetium  Roberto Zingales
The author is grateful for additional information that allowed him to correct an earlier mistake.
Zingales, Roberto. J. Chem. Educ. 2006, 83, 213.
Isotopes |
Nuclear / Radiochemistry |
Periodicity / Periodic Table
The History of Element 43—Technetium  Fathi Habashi
The article From Masurium to Trinacrium: The Troubled Story of Element 43 is the best story so far published about the history of technetium. There is, however, one paragraph on the right column of page 226 that is questionable.
Habashi, Fathi. J. Chem. Educ. 2006, 83, 213.
Isotopes |
Nuclear / Radiochemistry |
Periodicity / Periodic Table
The History of Element 43—Technetium  Fathi Habashi
The article From Masurium to Trinacrium: The Troubled Story of Element 43 is the best story so far published about the history of technetium. There is, however, one paragraph on the right column of page 226 that is questionable.
Habashi, Fathi. J. Chem. Educ. 2006, 83, 213.
Isotopes |
Nuclear / Radiochemistry |
Periodicity / Periodic Table
Stoichiometry of Calcium Medicines  Gabriel Pinto
Calcium supplements provide an excellent context in which to review most of the core content of general chemistry, namely, stoichiometry, concentration units, hydration of salts, inorganic and organic salts, physiological importance of elements, resonance in ions, geometry of polyatomic ions, and isomerism.
Pinto, Gabriel. J. Chem. Educ. 2005, 82, 1509.
Stoichiometry |
Applications of Chemistry |
Drugs / Pharmaceuticals |
Medicinal Chemistry
Based on a True Story: Using Movies as Source Material for General Chemistry Reports  Mark A. Griep and Marjorie L. Mikasen
Presents a list of one dozen, highly rated movies in which the focus is either a scientist's chemical research or the societal impact of some chemical compound. The method by which two of these movies were used as source material for a written report in a general chemistry course is described.
Griep, Mark A.; Mikasen, Marjorie L. J. Chem. Educ. 2005, 82, 1501.
Medicinal Chemistry |
Women in Chemistry |
Applications of Chemistry |
Drugs / Pharmaceuticals |
Industrial Chemistry |
Nonmajor Courses |
Nuclear / Radiochemistry
Measurement of the Isotopic Ratio of 10B/11B in NaBH4 by 1H NMR  Murray Zanger and Guillermo Moyna
A simple and remarkably accurate method for estimating the isotopic ratio between 10B and 11B through the use of 1H nuclear magnetic resonance (NMR) spectroscopy is presented. The experiment relies on the splitting caused by 10B (I = 3) and 11B (I = 3/2) on the 1H signal of a proton directly bound to boron, a phenomenon readily observed on an aqueous sample of NaBH4. In combination with a brief lecture or prelaboratory presentation, this laboratory can serve to introduce students to magnetic properties as well as theoretical and experimental aspects of NMR spectroscopy as early as the freshman-level chemistry.
Zanger, Murray; Moyna, Guillermo. J. Chem. Educ. 2005, 82, 1390.
Instrumental Methods |
Magnetic Properties |
NMR Spectroscopy |
Atomic Properties / Structure |
Isotopes
Some Footnotes on the History of Masurium  H. J. Wagner
Some additional comments on a recent article by R. Zingales about the history of element 43.
Wagner, H. J. J. Chem. Educ. 2005, 82, 1309.
Isotopes |
Nuclear / Radiochemistry |
Periodicity / Periodic Table
A Supramolecular Approach to Medicinal Chemistry: Medicine Beyond the Molecule  David K. Smith
This article emphasizes a conceptual view of medicinal chemistry, which has important implications for the future, as the supramolecular approach to medicinal-chemistry products outlined here is rapidly allowing nanotechnology to converge with medicine. In particular, this article discusses recent developments including the rational design of drugs such as Relenza and Tamiflu, the mode of action of vancomycin, and the mechanism by which bacteria develop resistance, drug delivery using cyclodextrins, and the importance of supramolecular chemistry in understanding protein aggregation diseases such as Alzheimer's and CreutzfieldJacob.
Smith, David K. J. Chem. Educ. 2005, 82, 393.
Drugs / Pharmaceuticals |
Noncovalent Interactions |
Medicinal Chemistry |
Nanotechnology |
Proteins / Peptides
Using Clinical Cases To Teach General Chemistry  Brahmadeo Dewprashad, Charles Kosky, Geraldine S. Vaz, and Charlotte L. Martin
This article describes how a fact-based clinical case was effectively used to motivate and enrich the classroom experience and review many of the concepts covered in general chemistry. The case involves an elderly patient who was brought to the emergency room. The results of his physical examination and laboratory analysis of his blood are presented. The students, in peer-led groups, work through the chemical principles involved in the doctor's diagnosis and treatment options for the patient. The article describes the case study, instructors' observations, and students' perception of the activity.
Dewprashad, Brahmadeo; Kosky, Charles; Vaz, Geraldine S.; Martin, Charlotte L. J. Chem. Educ. 2004, 81, 1471.
Acids / Bases |
Drugs / Pharmaceuticals |
Equilibrium |
Kinetics |
Medicinal Chemistry
How Radioactive Is Your Banana?  David W. Ball
This exercise uses a banana to illustrate the level of radioactivity (in this case, from K-40) in an everyday object.
Ball, David W. J. Chem. Educ. 2004, 81, 1440.
Food Science |
Nuclear / Radiochemistry |
Isotopes
Carbon Dioxide Flooding: A Classroom Case Study Derived from Surgical Practice  Robert C. Kerber
The surgical opening in open-heart surgery is often flooded with carbon dioxide gas to avoid air embolisms when the heart is closed and restarted. This practice can be used in chemistry courses to illustrate concepts of gas density, solubility, and acidbase equilibria, including buffering.
Kerber, Robert C. . J. Chem. Educ. 2003, 80, 1437.
Acids / Bases |
Aqueous Solution Chemistry |
Gases |
Medicinal Chemistry |
Nonmajor Courses |
Applications of Chemistry
An NMR-Smell Module for the First-Semester General Chemistry Laboratory  Erich S. Uffelman, Elizabeth H. Cox, J. Brown Goehring, Tyler S. Lorig, and C. Michele Davis
The series of experiments involves an exploration of organic stereochemistry via hands-on model building, several chemosensory smell tests, and hands-on use of 13C NMR, thus serving as a powerful interdisciplinary lab involving chemistry, physics, and neuroscience. Similarities and differences between NMR and MRI methods are emphasized.
Uffelman, Erich S.; Cox, Elizabeth H.; Goehring, J. Brown; Lorig, Tyler S.; Davis, C. Michele. J. Chem. Educ. 2003, 80, 1368.
NMR Spectroscopy |
Stereochemistry |
Molecular Modeling |
Medicinal Chemistry
Molecules, Miracles and Medicine
   by Andrew Lasslo
  Peggy Geiger
Brief histories of morphine, procaine, aspirin, barbital, sulfanilamide, penicillin, valium, and cortisone.
Geiger, Peggy. J. Chem. Educ. 2002, 79, 805.
Drugs / Pharmaceuticals |
Medicinal Chemistry
Drugs and the Human Body: With Implications for Society, 6th Edition
   by Ken Liska
  David J. A. Schedler
Facts about drug sources, history, action in the body, side effects, interactions, tolerance, abuse potential, dosage, dependency, delivery systems, and alternatives to drug use.
Schedler, David J. A. J. Chem. Educ. 2002, 79, 805.
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Applications of Chemistry
Modeling the Drug Discovery Process: The Isolation and Biological Testing of Eugenol from Clove Oil  William H. Miles and Patricia M. Smiley
Experiment that illustrates the principles of modern drug discovery.
Miles, William H.; Smiley, Patricia M. J. Chem. Educ. 2002, 79, 90.
Acids / Bases |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Natural Products |
Separation Science |
Applications of Chemistry
Blood-Chemistry Tutorials: Teaching Biological Applications of General Chemistry Material  Rachel E. Casiday, Dewey Holten, Richard Krathen, and Regina F. Frey
Four, Web-based tutorials that deal with chemical processes in the blood and provide an integrated biological context for a variety of chemical concepts.
Casiday, Rachel E.; Holten, Dewey; Krathen, Richard; Frey, Regina F. J. Chem. Educ. 2001, 78, 1210.
Applications of Chemistry |
Medicinal Chemistry |
Proteins / Peptides |
Acids / Bases |
Equilibrium |
Molecular Properties / Structure
Combinatorial Synthesis and Discovery of an Antibiotic Compound. An Experiment Suitable for High School and Undergraduate Laboratories  Scott E. Wolkenberg and Andrew I. Su
An experiment designed to introduce students to combinatorial chemistry as applied to drug discovery.
Wolkenberg, Scott E.; Su, Andrew I. J. Chem. Educ. 2001, 78, 784.
Aqueous Solution Chemistry |
Bioorganic Chemistry |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Synthesis |
Combinatorial Chemistry |
Applications of Chemistry
A Strategy for Incorporating Hands-On GC-MS into the General Chemistry Lecture and Laboratory Courses  Perry C. Reeves and Kim L. Pamplin
Students use the GC-MS to obtain spectra of the various halobenzenes. This vividly illustrates the differences in isotopic distributions of the halogens and the complications these differences present in calculating molar masses of compounds. The isotopic distribution of iron is then obtained from the mass spectrum of Fe(CO)5, and the students calculate the atomic mass of iron from this data.
Reeves, Perry C.; Pamplin, Kim L. J. Chem. Educ. 2001, 78, 368.
Chromatography |
Isotopes |
Mass Spectrometry |
Gas Chromatography |
Aromatic Compounds
No, the Molecular Mass of Bromobenzene Is Not 157 amu: An Exercise in Mass Spectrometry and Isotopes for Early General Chemistry  Steven M. Schildcrout
Even with no background in bonding and structure, students can successfully interpret the output of a modern research instrument. They learn to identify an isotope pattern, assign chemical formulas to ions giving mass spectral peaks, calculate an average atomic weight (for bromine) from measured isotopic abundances, and write balanced equations for ion fragmentation reactions.
Schildcrout, Steven M. J. Chem. Educ. 2000, 77, 1433.
Isotopes |
Mass Spectrometry |
Atomic Properties / Structure |
Molecular Properties / Structure
Two Faces of Alkaloids  Jirí Dostál
The article discusses and compares the salts and free bases of six well-known alkaloids: nicotine, morphine, cocaine, sanguinarine, allocryptopine, and magnoflorine. Relevance for the biological and medical uses of these compounds is emphasized.
Dostál, Jirí. J. Chem. Educ. 2000, 77, 993.
Acids / Bases |
Bioorganic Chemistry |
Drugs / Pharmaceuticals |
Natural Products |
Aromatic Compounds |
Medicinal Chemistry
Discovery and Early Uses of Iodine  Louis Rosenfeld
Therapeutic use of iodine, particularly in prevention and treatment of goiter.
Rosenfeld, Louis. J. Chem. Educ. 2000, 77, 984.
Medicinal Chemistry |
Descriptive Chemistry |
Applications of Chemistry
Synthesis of the Sweetener Dulcin from the Analgesic Tylenol  Brian D. Williams, Birute Williams, and Louise Rodino
A sequence suitable for the synthesis of the sweetener dulcin from the analgesic acetaminophen. The analgesic phenacetin is isolated during the synthesis as an intermediate and consequently the experiment can be adopted as a multistep synthesis or as either of two single-period transformations.
Williams, Brian D.; Williams, Birute; Rodino, Louise. J. Chem. Educ. 2000, 77, 357.
Synthesis |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Aromatic Compounds
Microwave Irradiation Reactions: Synthesis of Analgesic Drugs  Gholam A. Mirafzal and Jolene M Summer
Over-the-counter analgesics such as aspirin, acetanilide, phenacetin, and acetaminophen are conveniently prepared in a microwave at 30% power for five minutes. Recrystallization from appropriate solvents results in solid products in good to excellent yields.
Mirafzal, Gholam A.; Summer, Jolene M. J. Chem. Educ. 2000, 77, 356.
Drugs / Pharmaceuticals |
Synthesis |
Medicinal Chemistry |
Aromatic Compounds |
Amines / Ammonium Compounds |
Esters
Experiments with Aspirin  Londa L. Borer and Edward Barry
Experiments include (i) synthesis, purification, and characterization of aspirin by mp and TLC, (ii) percentage composition of a commercial aspirin tablet by titration, (iii) kinetics of the hydrolysis of aspirin to salicylic acid under various conditions, (iv) synthesis and characterization of copper(II) aspirinate and copper(II) salicylate, and (v) reaction of copper(II) aspirinate in aqueous solution.
Borer, Londa L.; Barry, Edward. J. Chem. Educ. 2000, 77, 354.
Synthesis |
Kinetics |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Aromatic Compounds
A Brine Shrimp Bioassay for Measuring Toxicity and Remediation of Chemicals  Marya Lieberman
A bioassay using brine shrimp was adapted to measure the toxicity of household chemicals. One project is described in which students collect dose-response curves for seven commercial flea-killing products. Next, groups of students researched the insecticidal ingredients of the flea products. On the basis of the structures of the active ingredients, they chose remediation methods to make the flea product less toxic to brine shrimp; procedures included copper-catalyzed hydrolysis, adsorption onto activated charcoal, bleach treatment, and photodegradation.
Lieberman, Marya. J. Chem. Educ. 1999, 76, 1689.
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Nonmajor Courses |
Toxicology
Henry's Law and Noisy Knuckles  Doris R. Kimbrough
Presented here is the application of Henry's law to the noise associated with "cracking" knuckles. Gases dissolved in the synovial fluid in joints rapidly come out of solution as the joint is stretched and pressure is decreased. This "cavitation" produces a characteristic noise.
Kimbrough, Doris R. J. Chem. Educ. 1999, 76, 1509.
Gases |
Solutions / Solvents |
Applications of Chemistry |
Medicinal Chemistry
The Chemical Adventures of Sherlock Holmes: The Death Puzzle at 221B Baker Street  Thomas R. Rybolt and Thomas G. Waddell
A chemical mystery featuring Sherlock Holmes and Dr. Watson.
Rybolt, Thomas R.; Waddell, Thomas G. J. Chem. Educ. 1999, 76, 489.
Enrichment / Review Materials |
Aqueous Solution Chemistry |
Medicinal Chemistry |
Qualitative Analysis
A Different Approach to a 3-D Periodic System Including Stable Isotopes  Alexandru T. Balaban
On a Periodic System with the two dimensions represented by Periods and Columns, one may stack each stable nuclide of an element along the third dimension. This "Downtown Area" representation is helpful for interconnecting concepts of: element, isotope or nuclide (stable vs. radioactive), atomic weight, atomic number, mass number.
Balaban, Alexandru T. J. Chem. Educ. 1999, 76, 359.
Periodicity / Periodic Table |
Isotopes |
Nuclear / Radiochemistry
Nucleogenesis! A Game with Natural Rules for Teaching Nuclear Synthesis and Decay  Donald J. Olbris and Judith Herzfeld
Nucleogenesis! is a simple and engaging game designed to introduce undergraduate physics or chemistry students to nuclear synthesis and decay by simulation of these processes. By playing the game, students become more familiar with nuclear reactions and the "geography" of the table of isotopes.
Olbris, Donald J.; Herzfeld, Judith. J. Chem. Educ. 1999, 76, 349.
Isotopes |
Nuclear / Radiochemistry |
Nonmajor Courses
Chemistry of the Heaviest Elements-One Atom at a Time  Darleane C. Hoffman and Diana M. Lee
A 75-year perspective of the chemistry of the heaviest elements, including a 50-year retrospective view of past developments, a summary of current research achievements and applications, and some predictions about exciting, new developments that might be envisioned within the next 25 years.
Hoffman, Darleane C.; Lee, Diana M. J. Chem. Educ. 1999, 76, 331.
Chromatography |
Instrumental Methods |
Isotopes |
Nuclear / Radiochemistry |
Separation Science |
Descriptive Chemistry |
Enrichment / Review Materials |
Atomic Properties / Structure
Enzyme-Linked Antibodies: A Laboratory Introduction to the ELISA  Gretchen L. Anderson and Leo A. McNellis
A fast and economical laboratory exercise is presented that qualitatively demonstrates the power of enzyme-linked antibodies to detect a specific antigen. Although ELISAs are commonly used in disease diagnosis in clinical settings, this application uses biotin, covalently attached to albumin, to take advantage of readily available reagents and avoids problems associated with potentially pathogenic antigens.
Anderson, Gretchen L.; McNellis, Leo A. J. Chem. Educ. 1998, 75, 1275.
Enzymes |
Nonmajor Courses |
Medicinal Chemistry
Production, Extraction, and Qualitative Testing of Penicillin: A Biochemistry Experiment for Health Science Chemistry Courses   Richard E. Stevens and Kara C. Billingsley
This laboratory procedure guides students through the growth of a submerged Penicillium chrysogenum culture. Subsequent steps include extraction of the penicillin by adsorption onto activated charcoal, extraction with acetone, and qualitative testing of the drug on a bacterial culture. The laboratory procedure is designed for freshman-level health science chemistry courses.
Stevens, Richard E.; Billingsley, Kara C. J. Chem. Educ. 1998, 75, 1264.
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Nonmajor Courses
Synthesis of Aspirin: A General Chemistry Experiment  John A. Olmsted III
An experiment is described that is suitable for the early portion of the laboratory in a general chemistry course and integrates organic examples. It is the two-step synthesis of aspirin starting from oil of wintergreen. The mechanism for this synthesis provides examples of three major classes of chemical reactions: hydrolysis, condensation, and proton transfer.
Olmsted, John A., III. J. Chem. Educ. 1998, 75, 1261.
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Mechanisms of Reactions |
Aromatic Compounds |
Carboxylic Acids |
Aldehydes / Ketones
The Art and Science of Organic and Natural Products Synthesis  K. C. Nicolaou, E. J. Sorensen, and N. Winssinger
In this article, the history of the art and science of organic and natural products synthesis is briefly reviewed and the state of the art is discussed. The impact of this discipline on biology and medicine is amply demonstrated with examples, and projections for future developments in the field are made.
Nicolaou, K. C.; Sorensen, E. J.; Winssinger, N. J. Chem. Educ. 1998, 75, 1225.
Natural Products |
Synthesis |
Medicinal Chemistry |
Applications of Chemistry |
Drugs / Pharmaceuticals
Vanillin (the author replies)  Hocking, Martin
Additional information regarding salicylic acid.
Hocking, Martin J. Chem. Educ. 1998, 75, 1203.
Aldehydes / Ketones |
Applications of Chemistry |
Medicinal Chemistry |
Molecular Properties / Structure
Vanillin  Calloway, Dean
Incorrect structural formula for methyl salicylate.
Calloway, Dean J. Chem. Educ. 1998, 75, 1203.
Medicinal Chemistry |
Applications of Chemistry |
Aldehydes / Ketones |
Molecular Properties / Structure
Letters  
Incorrect structural formula for methyl salicylate.
J. Chem. Educ. 1998, 75, 1203.
Medicinal Chemistry |
Applications of Chemistry |
Aldehydes / Ketones |
Molecular Properties / Structure
Fundamentals of General, Organic and Biological Chemistry, 2nd ed. by John McMurry and Mary E. Castellion  Lois B. Krause
This text, mainly intended as a general chemistry text for students in health or life science related majors, does a beautiful job of incorporating topics and examples to which students can relate.
Krause, Lois B. J. Chem. Educ. 1997, 74, 1279.
Medicinal Chemistry
Introduction to General, Organic and Biological Chemistry by Michael S. Matta, Antony C. Wilbraham, and Dennis D. Staley  Lois B. Krause
Intended specifically for undergraduate majors in health sciences, the primary aim of this text is to prepare students to understand the chemistry of the living cell.
Krause, Lois B. J. Chem. Educ. 1997, 74, 1277.
Medicinal Chemistry
Radioactivity in Everyday Life  S. G. Hutchison, F. I. Hutchison
This paper discusses the terminology appropriate to radiation exposure and dose, the three sources of natural background radiation (cosmic radiation, cosmogenic radiation, and terrestrial radiation), and several radioactive isotopes that are significant contributors to the radiation exposure received by individuals.
Hutchison, S. G.; Hutchison, F. I. J. Chem. Educ. 1997, 74, 501.
Learning Theories |
Nuclear / Radiochemistry |
Isotopes |
Consumer Chemistry
From the Research Laboratory to the Classroom: A Partners-in-Science Experience  Robert Zafran
This article describes the usage of two diametrically different, spherically shaped polymer balls known to science educators as Happy/Unhappy Balls. The unique property of the polynorbornene (Norsorex), "Unhappy" ball, its reluctance to bounce, is paired with the normally bouncing polychloroprene (neoprene) "Happy" ball to teach students observational skills necessary for the effective application of scientific reasoning processes needed for investigative analysis.
Zafran, Robert. J. Chem. Educ. 1996, 73, 78.
Isotopes
What Do College Students Know About Illegal Drugs?  Christine K. F. Hermann
Survey of student understanding of illegal drugs.
Hermann, Christine K. F. J. Chem. Educ. 1995, 72, 925.
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Enrichment / Review Materials
Chemistry for the Health Sciences, Seventh Edition (Sackheim, George I.; Lehman, Dennis D.)  Jache, Albert W.
Emphasis is placed on practical aspects of inorganic, organic, and biochemistry; theoretic topics are dealt with only as an aid to try to understand human bodily processes.
Jache, Albert W. J. Chem. Educ. 1994, 71, A132.
Nonmajor Courses |
Medicinal Chemistry
A Tale of Two Isotopes  Thomas, Nicolas C.
A clever tale describing the difference between oxygen and an oxygen isotope.
Thomas, Nicolas C. J. Chem. Educ. 1994, 71, 1013.
Isotopes
Not So Late Night Chemistry with USD  Koppang, Miles D.; Webb, Karl M.; Srinivasan, Rekha R.
Through the program, college students enhance their knowledge and expertise on a chemical topic and gain experience in scientific presentations. They also serve as role models to the high school students who can relate to college students more easily than the chemistry faculty members and their high school students.
Koppang, Miles D.; Webb, Karl M.; Srinivasan, Rekha R. J. Chem. Educ. 1994, 71, 929.
Forensic Chemistry |
Polymerization |
Electrochemistry |
Isotopes |
Acids / Bases
Risks and Chemical Substances  Blumberg, Avrom A.
We are exposed to about 50 thousand of the 12 million different substances that chemists have identified. This paper looks at how we become exposed within our homes, examine three important ways in which we identify and evaluate hazardous substances, and try to suggest a rational picture of the risks we face.
Blumberg, Avrom A. J. Chem. Educ. 1994, 71, 912.
Medicinal Chemistry
An Attack on the AIDS Virus: Inhibition of the HIV-1 Protease. New Drug Development Based on the Structure and Activity of the Protease and its Role in the Replication and Maturation of the Virus  Volker, Eugene J.
Article shows how research into the biochemistry of HIV may lead to a method for controlling its growth and maturation. This research illustrates some basic enzyme chemistry and holds student appeal due to the tie into current affairs.
Volker, Eugene J. J. Chem. Educ. 1993, 70, 3.
Bioorganic Chemistry |
Proteins / Peptides |
Medicinal Chemistry |
Molecular Biology
Argon-potassium atomic weight inversion in the periodic table.  Arnikar, H. J.
An explanation for the Ar-K inversion in terms of the nuclear characteristics of the naturally occurring isotopes of these elements.
Arnikar, H. J. J. Chem. Educ. 1992, 69, 687.
Periodicity / Periodic Table |
Nuclear / Radiochemistry |
Atomic Properties / Structure |
Geochemistry |
Isotopes
Phenol and the importance of dose.  Crute, Thomas D.
Phenol is highly toxic, but the active ingredient in Chloraseptic lozenges.
Crute, Thomas D. J. Chem. Educ. 1992, 69, 553.
Phenols |
Aromatic Compounds |
Alcohols |
Toxicology |
Consumer Chemistry |
Medicinal Chemistry
Views of nursing professionals on chemistry course content for nursing education  Walhout, Justine S.; Heinschel, Judie.
Analysis of survey conducted of deans of schools of nursing, chairs of nursing departments, and registered nurses regarding courses required of nursing students and the importance of different units of measure and 39 chemistry topics to the nursing profession.
Walhout, Justine S.; Heinschel, Judie. J. Chem. Educ. 1992, 69, 483.
Medicinal Chemistry |
Nomenclature / Units / Symbols
Advice from Allied Health faculty to chemistry faculty  Dever, David F.
Finding out what the different health professions would like to see from undergraduate chemistry programs.
Dever, David F. J. Chem. Educ. 1991, 68, 763.
Medicinal Chemistry |
Nuclear / Radiochemistry |
Nutrition |
Vitamins |
Gases
College Chemistry Faculties, Eighth Edition (Talmadge, Cornelia A., editor)  Kauffman, George B.
This book is a directory of two-year college, four-year college, and university teachers of chemistry, biochemistry, medicinal/pharmaceutical chemistry, and chemical engineering in the United States and Canada.
Kauffman, George B. J. Chem. Educ. 1990, 67, A151.
Medicinal Chemistry |
Administrative Issues
Dramatizing isotopes: Deuterated ice cubes sink   Ellis, Arthur B.; Adler, Edward A.; Juergens, Frederick H.
The authors describe a safe, striking demonstration of the effect of isotopic substitution.
Ellis, Arthur B.; Adler, Edward A.; Juergens, Frederick H. J. Chem. Educ. 1990, 67, 159.
Water / Water Chemistry |
Isotopes
A student experiment to demonstrate the energy loss and straggling of electrons in matter  de Bruin, M.; Huijgen, F. W. J.
The experiment described has been applied routinely for several years in introductory courses in the application of radiation and isotopes. The results obtained give direct insight into the characteristics of the phenomena associated with the absorption of energetic electrons in matter.
de Bruin, M.; Huijgen, F. W. J. J. Chem. Educ. 1990, 67, 86.
Atomic Properties / Structure |
Nuclear / Radiochemistry |
Isotopes
American Chemical Society Directory of Graduate Research, 1987 (The ACS Committee on Professional Training)  Kauffman, George B.
This latest edition contains a wealth of information on 668 universities and colleges in the United States and Canada that offer bachelor's and master's curricula in chemistry; chemical engineering; pharmaceutical and medicinal chemistry; clinical chemistry; and polymer science.
Kauffman, George B. J. Chem. Educ. 1989, 66, A47.
Medicinal Chemistry
Predicting nuclear stability using the periodic table  Blanck, Harvey F.
Develops several empirical rules to use with the periodic table as an aid to recalling those nuclides that are stable.
Blanck, Harvey F. J. Chem. Educ. 1989, 66, 757.
Nuclear / Radiochemistry |
Periodicity / Periodic Table |
Isotopes
What is an element?  Roundy, Willard H., Jr.
Problems with using outdated definitions of what constitutes an element.
Roundy, Willard H., Jr. J. Chem. Educ. 1989, 66, 729.
Isotopes |
Atomic Properties / Structure
Teaching the skills of science - gold and anemia  Mattson, William
A student poses a question that leads to classroom inquiry: Why does gold rubbed on the face of an anemic person leave a dark mark?
Mattson, William J. Chem. Educ. 1988, 65, 1000.
Bioinorganic Chemistry |
Medicinal Chemistry |
Applications of Chemistry
Oxalate blockage of calcium and iron: A student learning activity  Walker, Noojin
The topics of iron deficiency anemia and osteoporosis entice student attention and can be used to construct meaningful learning activities about percent composition, mole concept, selective precipitation, and limiting factors.
Walker, Noojin J. Chem. Educ. 1988, 65, 533.
Medicinal Chemistry |
Stoichiometry |
Plant Chemistry |
Bioanalytical Chemistry |
Bioinorganic Chemistry
Determining the solubility of Ca(OH)2 using 45Ca as a tracer  Edmiston, Michael D.; Suter, Robert W.
These authors have developed a simple lab that can be incorporated into freshman chemistry that allows students to understand the power of radiochemistry as an analytical tool as well as gain perspectives about real versus imagined dangers of radioactivity.
Edmiston, Michael D.; Suter, Robert W. J. Chem. Educ. 1988, 65, 279.
Nuclear / Radiochemistry |
Medicinal Chemistry
General, Organic & Biological Chemistry, Study Guide and Solutions Manual (Feigl, Dorothy M.; Hill, John W.)  Taylor, R. Craig
Written for students in the health and life science and intended for students who have had little or no chemistry background.
Taylor, R. Craig J. Chem. Educ. 1987, 64, A327.
Nonmajor Courses |
Medicinal Chemistry
Chemistry for the allied health students  Williams, Donald H.
Review of the recent educational literature regarding chemistry for allied health students; includes a suggested outline for a year-long course.
Williams, Donald H. J. Chem. Educ. 1987, 64, 707.
Nonmajor Courses |
Medicinal Chemistry
A syllabus for a two-semester chemistry course for health professions: Report of the committee on chemical education for the health professions  Daly, John M.; Sarquis, Jerry L.
Outline of a two-semester chemistry course for health professions.
Daly, John M.; Sarquis, Jerry L. J. Chem. Educ. 1987, 64, 699.
Nonmajor Courses |
Medicinal Chemistry
Hemoglobinometry: A biochemistry experiment that utilizes the principles of transition metal chemistry  Giuliano, Vincenzo
Colorimetric measurements are used to determine the concentration of hemoglobin in blood and the effect of the effect that the presence of cyanide ions has on the formation of cyanomethemoglobin.
Giuliano, Vincenzo J. Chem. Educ. 1987, 64, 354.
Transition Elements |
Metals |
Medicinal Chemistry |
Spectroscopy
Radioactive dating: A method for geochronology  Rowe, M. W.
The discovery of radioactivity, radioactive dating, and various dating methods.
Rowe, M. W. J. Chem. Educ. 1985, 62, 580.
Geochemistry |
Nuclear / Radiochemistry |
Isotopes |
Mass Spectrometry
Nuclear synthesis and identification of new elements  Seaborg, Glenn T.
Review of descriptive terms, nuclear reactions, radioactive decay modes, and experimental methods in nuclear chemistry.
Seaborg, Glenn T. J. Chem. Educ. 1985, 62, 392.
Nuclear / Radiochemistry |
Nomenclature / Units / Symbols |
Isotopes
Consumer applications of chemical principles: Drugs  Hill, John W.; Jones, Susan M.
Acid-base chemistry of drugs (nicotine, cocaine, and aspirin), general anesthesia (nitrous oxide, enflurane, isoflurane, halothane), local anesthetics (procaine, lidocaine, cocaine), and intravenous anesthetics (thiopental, ketamine hydrochloride, phencyclidine).
Hill, John W.; Jones, Susan M. J. Chem. Educ. 1985, 62, 328.
Consumer Chemistry |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Acids / Bases |
Applications of Chemistry
Drug stabilization against oxidative degradation  Akers, Michael J.
Describes the process of oxidation and ways in which pharmaceutical preparations can be protected from oxidative degredation.
Akers, Michael J. J. Chem. Educ. 1985, 62, 325.
Drugs / Pharmaceuticals |
Oxidation / Reduction |
Medicinal Chemistry |
Nonmajor Courses
Organic chemistry for health-science students (the authors reply)  Genyea, Julien; Callewaert, Denis
Importance of time limitations in teaching general, organic, and biochemistry in a two-semester course.
Genyea, Julien; Callewaert, Denis J. Chem. Educ. 1985, 62, 272.
Medicinal Chemistry |
Nonmajor Courses
Organic chemistry for health-science students   Schumm, Margot K.
It is important to teach health-science students reaction mechanisms when teaching them organic and biochemistry.
Schumm, Margot K. J. Chem. Educ. 1985, 62, 272.
Medicinal Chemistry |
Nonmajor Courses |
Mechanisms of Reactions
Chemistry instruction using evening news video tape segments  Greenberg, Fred G.
Evening newscasts often provide current, dramatic, and meaningful applications of basic chemical principles.
Greenberg, Fred G. J. Chem. Educ. 1985, 62, 227.
Medicinal Chemistry |
Applications of Chemistry
Chemistry for Health-Related Sciences; Concepts and Correlations, Second Edition (Sears, Curtis T.; Stanitski, Conrad L.)  Meloy, Carl R.
Designed for a two-term chemistry course for students in health-related programs.
Meloy, Carl R. J. Chem. Educ. 1984, 61, A221.
Noncovalent Interactions |
Medicinal Chemistry
A syllabus for a one semester chemistry course for health professions: Report of the Task Force on Chemical Education for Health Professions  Treblow, Mordecai; Daly, John M.; Sarquis, Jerry L.
Goals and outline of topics for a one semester chemistry course for health professions.
Treblow, Mordecai; Daly, John M.; Sarquis, Jerry L. J. Chem. Educ. 1984, 61, 620.
Medicinal Chemistry |
Nonmajor Courses
Chemistry for health-science students: what is an appropriate balance between basic chemical concepts and health-related applications?  Genyea, Julien; Callewaert, Denis M.
The curricular suggestions made in this paper stem from the authors' experience developing, and teaching, a sequence of chemistry courses to meet the needs of nursing students. It is believed that these suggestions apply equally well for students who intend to pursue professional careers in other health-science areas.
Genyea, Julien; Callewaert, Denis M. J. Chem. Educ. 1983, 60, 471.
Nonmajor Courses |
Medicinal Chemistry
General, Organic and Biochemistry (Brown, William H.; Rogers, Elizabeth)  Haag, William L.
Directed toward those interested in the health sciences.
Haag, William L. J. Chem. Educ. 1982, 59, A64.
Nonmajor Courses |
Medicinal Chemistry
Chemistry for the Health Professions (Henrickson, Charles H.; Byrd, L. C.)  Laughlin, Etheireda
A one-year chemistry text for a variety of paramedical programs.
Laughlin, Etheireda J. Chem. Educ. 1982, 59, A26.
Nonmajor Courses |
Medicinal Chemistry
On the use of intravenous solutions to teach some principles of solution chemistry  Shapiro, Irwin L.
A series of laboratory periods are devoted to the chemistry of intravenous solution in a one-semeter course for nursing students.
Shapiro, Irwin L. J. Chem. Educ. 1982, 59, 725.
Solutions / Solvents |
Nonmajor Courses |
Medicinal Chemistry
A method for the determination of half-lives of long lived radioisotopes  Muse, Lowell A.; Safter, Warren J.
It is possible to obtain a rather accurate estimate of the half-life of long-lived radioisotopes by absolute counting of a sample of known mass.
Muse, Lowell A.; Safter, Warren J. J. Chem. Educ. 1982, 59, 431.
Isotopes |
Nuclear / Radiochemistry |
Laboratory Management
"Holey" crystals!   Feinstein, H. I.
Nonstoichiometric compounds have a range of composition, often exhibit unusual color, luster, fluorescence, and semi-conductance. This makes them fascinating compounds for student study.
Feinstein, H. I. J. Chem. Educ. 1981, 58, 638.
Stoichiometry |
Semiconductors |
Crystals / Crystallography |
Physical Properties |
Isotopes
It's beanium!!   Miller, Gregory C.
Pinto, navy, and blackeye beans can be used to help students develop a macroscopic understanding of how isotopes are calculated.
Miller, Gregory C. J. Chem. Educ. 1981, 58, 507.
Isotopes
Some aspects of coordination chemistry   Mickey, Charles D.
The genesis of modern coordination theory; the Wernerian system; experimental support for Werner's coordination theory; amplification of Werner's theory; the nature of complex ions; formation and nomenclature for complexes, complexes in the environment; chelates in medicine; complexing in natural systems; and industrial application of complexes.
Mickey, Charles D. J. Chem. Educ. 1981, 58, 257.
Coordination Compounds |
Medicinal Chemistry |
Metals
California earthquakes: Predicting the next big one using radiocarbon dating  DeLorenzo, Ron
Using real data to predict California earthquakes using radiocarbon dating. [Debut]
DeLorenzo, Ron J. Chem. Educ. 1980, 57, 601.
Applications of Chemistry |
Geochemistry |
Nuclear / Radiochemistry |
Isotopes
Magical sand  Smith, Douglas D.

Smith, Douglas D. J. Chem. Educ. 1980, 57, 363.
Applications of Chemistry |
Medicinal Chemistry
The case of the isotopic artist  O'Connor, Rod
A problem regarding the decay of isotopes in pigments used to determine an art forgery.
O'Connor, Rod J. Chem. Educ. 1980, 57, 271.
Isotopes |
Nuclear / Radiochemistry |
Applications of Chemistry |
Dyes / Pigments
Drugs in the chemistry laboratory: The conversion of acetaminophen into phenacetin  Volker, Eugene J.; Pride, Ernest; Hough, Charles
The phenolic alcohol group of acetaminophen is alkylated with ethyl iodide using the basic catalyst K2CO3.
Volker, Eugene J.; Pride, Ernest; Hough, Charles J. Chem. Educ. 1979, 56, 831.
Nonmajor Courses |
Applications of Chemistry |
Medicinal Chemistry |
Drugs / Pharmaceuticals |
Synthesis |
Catalysis |
Phenols |
Alcohols
Some biochemistry of sedatives  J. Chem. Educ. Staff
Antianxiety agents / sleep reducers, the discovery of sedatives and their chemistry, and biological responses to sedatives.
J. Chem. Educ. Staff J. Chem. Educ. 1979, 56, 402.
Drugs / Pharmaceuticals |
Applications of Chemistry |
Medicinal Chemistry
Medicinal chemistry of aspirin and related drugs  J. Chem. Educ. Staff
Nonprescription analgesics, the discovery of aspirin, pain and analgesic activity, inflammation and the role of chemical agents, fever and its reduction, aspirin in stroke prevention, and toxicity and side effects.
J. Chem. Educ. Staff J. Chem. Educ. 1979, 56, 331.
Applications of Chemistry |
Medicinal Chemistry |
Drugs / Pharmaceuticals |
Toxicology
Thin layer chromatographic separation of common analgesics - A consumer experiment  Cormier, Russell A.; Hudson, William B.; Siegel, Jay A.
A simple method for determining which analgesics have which ingredients.
Cormier, Russell A.; Hudson, William B.; Siegel, Jay A. J. Chem. Educ. 1979, 56, 180.
Consumer Chemistry |
Chromatography |
Separation Science |
Medicinal Chemistry |
Qualitative Analysis
Molar volumes: Microscopic insight from macroscopic data  Davenport, Derek A.; Fosterling, Robert B.; Srinivasan, Viswanathan
The molar volumes of the alkali metal halides; molar volumes of binary hydrogen compounds; molar volumes of the first transition series; molar volumes of the lanthanoids and actinoids; molar volumes of the carbon family; molar volumes of isotopically related species; aquated ions and ions in aqueous solution.
Davenport, Derek A.; Fosterling, Robert B.; Srinivasan, Viswanathan J. Chem. Educ. 1978, 55, 93.
Inner Transition Elements |
Metals |
Periodicity / Periodic Table |
Stoichiometry |
Gases |
Transition Elements |
Aqueous Solution Chemistry |
Isotopes
Elemental evolution and isotopic composition  Rydberg, J.; Choppin, G. R.
Reviews elemental abundances and the processes of elemental creation.
Rydberg, J.; Choppin, G. R. J. Chem. Educ. 1977, 54, 742.
Astrochemistry |
Periodicity / Periodic Table |
Atomic Properties / Structure |
Isotopes |
Nuclear / Radiochemistry |
Geochemistry
What is an element?  Kolb, Doris
Reviews the history of the discovery, naming, and representation of the elements; the development of the spectroscope and the periodic table; radioactive elements and isotopes; allotropes; and the synthesis of future elements.
Kolb, Doris J. Chem. Educ. 1977, 54, 696.
Periodicity / Periodic Table |
Nuclear / Radiochemistry |
Nomenclature / Units / Symbols |
Isotopes
Copper(II) aspirinate project for the general chemistry laboratory  Dudek, Emily
The weight percent of copper in student-prepared copper(II) aspirinate is measured by electrogravimetric, spectrophotometric, and titrimetric methods.
Dudek, Emily J. Chem. Educ. 1977, 54, 329.
Titration / Volumetric Analysis |
Medicinal Chemistry |
Drugs / Pharmaceuticals |
Synthesis |
Quantitative Analysis
The effects of HCl and aspirin on the stomach: An equilibrium review  DeLorenzo, Ronald
The chemical effect and medical implications of taking aspirin.
DeLorenzo, Ronald J. Chem. Educ. 1977, 54, 306.
Equilibrium |
Acids / Bases |
pH |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Applications of Chemistry
Questions [and] Answers  Campbell, J. A.
290-297. Eight questions regarding practical applications of chemistry, primarily in the medical field, and their answers.
Campbell, J. A. J. Chem. Educ. 1977, 54, 247.
Toxicology |
Equilibrium |
Metabolism |
Medicinal Chemistry |
Applications of Chemistry |
Enrichment / Review Materials
Questions [and] Answers  Campbell, J. A.
284-289. Six questions and their answers on practical applications of chemistry.
Campbell, J. A. J. Chem. Educ. 1977, 54, 161.
Medicinal Chemistry |
Enzymes |
Nuclear / Radiochemistry |
Drugs / Pharmaceuticals |
Applications of Chemistry |
Enrichment / Review Materials
Some iron anecdotes  Ainscough, E. W.; Brodie, A. M.
When introducing the bioinorganic chemistry of iron, this anecdote can be use to illustrate one of the earliest applications of iron therapy (1500 B.C.).
Ainscough, E. W.; Brodie, A. M. J. Chem. Educ. 1976, 53, 646.
Bioinorganic Chemistry |
Medicinal Chemistry
Minicourses in chemistry  Lygre, D. G.; Hasbrouck, R. W.; Gaines, R. D.; Duncan, L. C.; Habib, H. S.; Meany, J. E.; Newschwander, W. W.
Briefly describes a variety of minicourses designed to acquaint students with practical applications of chemistry in everyday experiences.
Lygre, D. G.; Hasbrouck, R. W.; Gaines, R. D.; Duncan, L. C.; Habib, H. S.; Meany, J. E.; Newschwander, W. W. J. Chem. Educ. 1975, 52, 735.
Consumer Chemistry |
Medicinal Chemistry |
Nuclear / Radiochemistry |
Plant Chemistry |
Agricultural Chemistry |
Applications of Chemistry |
Food Science
Questions [and] Answers  Campbell, J. A.
193-197. Five biochemical questions and their answers.
Campbell, J. A. J. Chem. Educ. 1975, 52, 457.
Enrichment / Review Materials |
pH |
Isotopes |
Water / Water Chemistry
A new chemistry program for nursing and allied health students  Stanitski, Conrad L.; Sears, Curtis T., Jr.
Outlines and discusses the topics considered in a chemistry program for nursing and allied health students.
Stanitski, Conrad L.; Sears, Curtis T., Jr. J. Chem. Educ. 1975, 52, 226.
Nonmajor Courses |
Applications of Chemistry |
Medicinal Chemistry |
Oxidation / Reduction |
Catalysis |
Acids / Bases |
pH |
Metabolism |
Drugs / Pharmaceuticals
An audio-tutorial program in allied health chemistry  Laughlin, Ethelreda; Kurnath, Norbert
Describes the nature and use of an audio-tutorial program in allied health chemistry.
Laughlin, Ethelreda; Kurnath, Norbert J. Chem. Educ. 1975, 52, 75.
Nonmajor Courses |
Medicinal Chemistry
New directions for the traditional curriculum. Session III-A: Chemistry for the preprofessional students  Plumb, Robert C.; Whidden, Helen L.; Davis, Fred W.
Freshman chemistry for engineers; biology majors in the general chemistry course; undergraduate organic chemistry; chemical concepts in allied health; and chemistry for nursing majors.
Plumb, Robert C.; Whidden, Helen L.; Davis, Fred W. J. Chem. Educ. 1973, 50, 23.
Conferences |
Professional Development |
Nonmajor Courses |
Medicinal Chemistry
Radiometric analysis of ammonia in water  Mehra, M. C.
In this experiment, the silver concentration in aqueous solution is determined radiometrically using silver-110 as the radiotracer.
Mehra, M. C. J. Chem. Educ. 1972, 49, 837.
Water / Water Chemistry |
Nuclear / Radiochemistry |
Isotopes |
Aqueous Solution Chemistry |
Quantitative Analysis
Chemistry in art. Radiochemistry and forgery  Rogers, F. E.
It wasn't until a radiochemical analysis in 1968 that a 1937 forgery of a 17th century Dutch master was confirmed as a fake.
Rogers, F. E. J. Chem. Educ. 1972, 49, 418.
Applications of Chemistry |
Nuclear / Radiochemistry |
Isotopes
Questions [and] Answers  Campbell, J. A.
Five questions requiring an application of basic chemical principles.
Campbell, J. A. J. Chem. Educ. 1972, 49, 328.
Enrichment / Review Materials |
Applications of Chemistry |
Nuclear / Radiochemistry |
Thermodynamics |
Mass Spectrometry |
Isotopes
Pain: A chemical explanation  Plumb, Robert C.; Lindahl, Olov
In sensing pain the nervous system acts like a pH meter.
Plumb, Robert C.; Lindahl, Olov J. Chem. Educ. 1972, 49, 179.
pH |
Acids / Bases |
Applications of Chemistry |
Medicinal Chemistry
Sickle-cell anemia, hemoglobin solubility and resistance to malaria  Martin, David L.; Huheey, James E.
The phenomenon of erythrocytic sickling is of considerable pedagogical usefulness since it provides a bridge of relevance between chemistry and biology.
Martin, David L.; Huheey, James E. J. Chem. Educ. 1972, 49, 177.
Proteins / Peptides |
Medicinal Chemistry |
Applications of Chemistry
Beer, acetone, and diabetes: A story and a demonstration  Isenberg, Norbert
Acetone causes the collapse of beer foam.
Isenberg, Norbert J. Chem. Educ. 1972, 49, 151.
Aldehydes / Ketones |
Medicinal Chemistry
Using alligation alternate to solve composition problems  Mancott, Anatol
Problems involving the composition of mixtures may be solved by using the relatively obscure method of "alligation alternate" in lieu of the standard algebraic procedure with no loss in accuracy; includes five examples.
Mancott, Anatol J. Chem. Educ. 1972, 49, 57.
Chemometrics |
Solutions / Solvents |
Isotopes
Isotopy. A general chemistry experiment  Ehlert, Thomas C.
The author describes an inexpensive paper-and-pencil experiment which has been used successfully as the first experiment in an introductory course for nonmajors.
Ehlert, Thomas C. J. Chem. Educ. 1971, 48, 273.
Nonmajor Courses |
Isotopes
Chemical queries. Especially for introductory chemistry teachers  Young, J. A.; Malik, J. G.; Parris, Michael
(1) Explains how free radicals differ from species such as NO3- and NH4+. (2) Explains why HI is a stronger acid than HF in aqueous solution. - answer by Parris. (3) Explains that it is possible to alter the half-life of a some radioactive processes through chemical means.
Young, J. A.; Malik, J. G.; Parris, Michael J. Chem. Educ. 1970, 47, 697.
Free Radicals |
Acids / Bases |
Aqueous Solution Chemistry |
Nuclear / Radiochemistry |
Isotopes
An introduction to nuclear power in a freshman chemistry course  Teeter, Charles E.
Describes how one instructor has included an introduction to nuclear power in his freshman chemistry course.
Teeter, Charles E. J. Chem. Educ. 1970, 47, 208.
Nuclear / Radiochemistry |
Applications of Chemistry |
Isotopes
Nuclear experiments in the chemistry curriculum  Clark, Herbert M.
Outlines types of nuclear teaching experiments, suggests where they might be placed in the undergraduate chemistry curriculum, and considers the costs of needed instruments and materials.
Clark, Herbert M. J. Chem. Educ. 1970, 47, 203.
Nuclear / Radiochemistry |
Isotopes
Chemical queries. Especially for introductory chemistry teachers  Young, J. A.; Malik, J. G.; Choppin, Gregory R.; Young, J. P.
(1) Is there more to nuclear stability than only the neutron to proton ration? - answer by Choppin. (2) What are the products generated by the electrolysis of molten potassium nitrate with stainless steel electrodes? - answer by Young.
Young, J. A.; Malik, J. G.; Choppin, Gregory R.; Young, J. P. J. Chem. Educ. 1970, 47, 73.
Nuclear / Radiochemistry |
Isotopes |
Atomic Properties / Structure |
Electrochemistry
Stable isotopes of the atmosphere  Eck, C. F.
This article briefly presents the composition of air, the discovery of isotopes, their concentration in air, and reviews their current enrichment status.
Eck, C. F. J. Chem. Educ. 1969, 46, 706.
Atmospheric Chemistry |
Isotopes |
Nuclear / Radiochemistry
Chemistry for the Health Sciences (Sackheim, George I.; Schultz, Ronald M.)  Caraway, Kathryn, P.

Caraway, Kathryn, P. J. Chem. Educ. 1969, 46, 702.
Medicinal Chemistry |
Nonmajor Courses
General chemistry demonstrations based on nuclear and radiochemical phenomena  Herber, Rolfe H.
This paper is intended to provide a brief survey of lecture demonstrations, suitable for a general chemistry course, that incorporate some of the ideas, concepts, techniques, and instrumentation of the field of nuclear and radiochemistry.
Herber, Rolfe H. J. Chem. Educ. 1969, 46, 665.
Nuclear / Radiochemistry |
Isotopes
Radioisotope generators for introductory laboratory use  Crater, H. L.; Macchione, J. B.; Gemmill, W. J.; Kramer, H. H.
Describes the use of simple radioisotope generators in 23 different experiments involving nuclear theory.
Crater, H. L.; Macchione, J. B.; Gemmill, W. J.; Kramer, H. H. J. Chem. Educ. 1969, 46, 287.
Nuclear / Radiochemistry |
Isotopes |
Laboratory Equipment / Apparatus
To the editor  Boig, Fletcher S.
We do non-chemistry majors a serious disservice by attempting to make career chemists of them.
Boig, Fletcher S. J. Chem. Educ. 1968, 45, 813.
Nonmajor Courses |
Medicinal Chemistry
Laboratory design considerationsPart II  Steere, Norman V.
Considers ventilation, illumination, radioisotopes, egress, water supply, and miscellaneous laboratory design features.
Steere, Norman V. J. Chem. Educ. 1965, 42, A665.
Laboratory Management |
Laboratory Equipment / Apparatus |
Nuclear / Radiochemistry |
Isotopes
Solubility in mixed solvents: A radiochemistry experiment  Lochmuller, C.; Cefola, M.
This experiment illustrates the use of radioisotopes in a solubility measurement and demonstrates the effect of solvent dielectric on solubility.
Lochmuller, C.; Cefola, M. J. Chem. Educ. 1964, 41, 604.
Nuclear / Radiochemistry |
Isotopes |
Precipitation / Solubility
Demonstration of a parent-daughter radioactive equilibrium using 137Cs-137mBa  Choppin, Gregory R.; Nealy, Carson L.
Demonstrates the relationship between radioactive half life and both the rate of decay and growth of a radioactive daughter.
Choppin, Gregory R.; Nealy, Carson L. J. Chem. Educ. 1964, 41, 598.
Isotopes |
Nuclear / Radiochemistry |
Equilibrium |
Rate Law
A kinetics experiment for first year chemistry  Shaefer, William P.
The exchange of iodine atoms between organic and inorganic iodides serves as a kinetics experiment for first year chemistry.
Shaefer, William P. J. Chem. Educ. 1964, 41, 558.
Kinetics |
Isotopes |
Rate Law
Dating of uranium minerals by the specific radioactivity of lead  Fairhall, A. W.
This paper discusses a method for estimating the age of a uranium mineral without recourse to elaborate mass-spectrometric techniques and presents an experimental procedure for doing so.
Fairhall, A. W. J. Chem. Educ. 1963, 40, 626.
Nuclear / Radiochemistry |
Isotopes |
Geochemistry
Radioisotope demonstration of common ion effect on solubility  Roig, E.; Rieckehoff, I. C.; Russo, G. S.; Curet, J. D.
This paper reports a direct demonstration of the effect of common ion concentration on the solubility of a uni-univalent salt, thallium(I) chloride.
Roig, E.; Rieckehoff, I. C.; Russo, G. S.; Curet, J. D. J. Chem. Educ. 1961, 38, 350.
Aqueous Solution Chemistry |
Precipitation / Solubility |
Nuclear / Radiochemistry |
Isotopes
Incorporating radioisotope techniques into the chemistry curriculum  Radin, Norman S.
Presents a list of radioisotope experiments suitable for a wide range of different domains and levels in chemistry.
Radin, Norman S. J. Chem. Educ. 1961, 38, 344.
Nuclear / Radiochemistry |
Isotopes
AlkaloidsThe world's pain killers  Ray, R. L.
Examines the history and properties of the alkaloids, including morphine, strychnine, and curare.
Ray, R. L. J. Chem. Educ. 1960, 37, 451.
Medicinal Chemistry
Nuclear and radiochemistry in the curriculum in general chemistry  Garrett, A. B.
The author summarizes how he integrates nuclear and radiochemistry into the general chemistry curriculum.
Garrett, A. B. J. Chem. Educ. 1960, 37, 384.
Nuclear / Radiochemistry |
Isotopes
Acceleration of biochemical research by recent analytical developments  Anthony, David S.
The development of several kinds of chromatography and the wide spread availability of isotopes as well as associated counting equipment permitted experimentation in areas that could not previously be explored.
Anthony, David S. J. Chem. Educ. 1959, 36, 540.
Chromatography |
Ion Exchange |
Gas Chromatography |
Isotopes |
Nuclear / Radiochemistry
A half-life experiment for general chemistry students  Smith, W. T.; Wood, J. H.
This paper describes the authors' experiences with the measurement of the half-life of bismuth-210.
Smith, W. T.; Wood, J. H. J. Chem. Educ. 1959, 36, 492.
Nuclear / Radiochemistry |
Isotopes
Separation of Ce144 from Pr144: A radiochemistry demonstration  Bradley, Arthur; Adamowicz, Michael
This demonstration/experiment involves the separation of two radioisotopes through filtration of an insoluble precipitate.
Bradley, Arthur; Adamowicz, Michael J. Chem. Educ. 1959, 36, 136.
Isotopes |
Separation Science
Use of radioisotopes in the college chemistry laboratory  Phillips, David; Maybury, Robert H.
Provides experiments and experiences working with constructed Geiger counters and radioisotopes.
Phillips, David; Maybury, Robert H. J. Chem. Educ. 1959, 36, 133.
Nuclear / Radiochemistry |
Isotopes |
Instrumental Methods |
Qualitative Analysis |
Kinetics
Radioisotopes on your rooftop  Lockhart, Luther, B., Jr.
The collection, recovery, and measurement of radioactive materials from atomic testing can be done through the use of relatively simple procedures and is a good exercise in tracer chemistry.
Lockhart, Luther, B., Jr. J. Chem. Educ. 1957, 34, 602.
Nuclear / Radiochemistry |
Atmospheric Chemistry |
Isotopes
Demonstration of dynamic nature of ions using I131  Blake, Richard F.
This demonstration presents visual evidence of the ionic nature of solid salts and the dynamic equilibrium existing between dissolved and undissolved ions.
Blake, Richard F. J. Chem. Educ. 1956, 33, 354.
Isotopes |
Aqueous Solution Chemistry |
Solids |
Precipitation / Solubility |
Equilibrium
Atomic-weight variations in nature  Boggs, James E.
Atoms of the same element may have different masses (due to isotopic differences) depending on their source.
Boggs, James E. J. Chem. Educ. 1955, 32, 400.
Atomic Properties / Structure |
Nuclear / Radiochemistry |
Isotopes
The elementary composition of the earth's crust  Asimov, Isaac
Identifies the elementary composition of the earth's crust in terms of atom number, weight, and nuclides.
Asimov, Isaac J. Chem. Educ. 1954, 31, 70.
Geochemistry |
Isotopes
The relative contributions of various elements to the earth's radioactivity  Asimov, Isaac
Describes relative contributions of various elements to the earth's radioactivity.
Asimov, Isaac J. Chem. Educ. 1954, 31, 24.
Nuclear / Radiochemistry |
Geochemistry |
Isotopes
Dating with carbon 14  Kulp, J. Laurence
Examines the principles, technique, results of and problems with radioactive dating using carbon-14.
Kulp, J. Laurence J. Chem. Educ. 1953, 30, 432.
Nuclear / Radiochemistry |
Isotopes
Naturally occurring radioisotopes  Asimov, Isaac
Examines half-life calculations, long-lived radioactive isotopes, and the formation of short-lived radioactive isotopes.
Asimov, Isaac J. Chem. Educ. 1953, 30, 398.
Nuclear / Radiochemistry |
Isotopes |
Geochemistry
Recent history of the notion of a chemical species  Bulloff, Jack J.
Quantum and nuclear chemistry have challenged the doctrine that chemical elements are homogeneous entities while studies of the structure and stoichiometry of solids invite a change in our ideas of definite proportions in chemical combinations.
Bulloff, Jack J. J. Chem. Educ. 1953, 30, 78.
Nuclear / Radiochemistry |
Isotopes |
Stoichiometry |
Solids
Radiations from radioactive materials  Orban, Edward
Lists many radioactive minerals and ores and their sources and describes some simple demonstrations of radioactivity.
Orban, Edward J. Chem. Educ. 1952, 29, 289.
Nuclear / Radiochemistry |
Isotopes
Experiments on radioactivity in the first course in college chemistry  Brown, Charles A.; Rochow, E. G.
Experiments described include the detection and measurement of radioactivity; comparing the penetrative power of beta and gamma radiation; separating thorium from uranium; and determining the half-life of iodine 128.
Brown, Charles A.; Rochow, E. G. J. Chem. Educ. 1951, 28, 521.
Nuclear / Radiochemistry |
Isotopes |
Separation Science