| Journal Articles: 23 results |
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The A1c Blood Test: An Illustration of Principles from General and Organic Chemistry Robert C. Kerber
The glycated hemoglobin blood test is a key measure of the effectiveness of glucose control in diabetics. The chemistry of glucose in the bloodstream, which underlies the test and its impact, provides an illustration of the importance of chemical equilibrium and kinetics to a major health problem.
Kerber, Robert C. . J. Chem. Educ. 2007, 84, 1541.
Applications of Chemistry |
Bioinorganic Chemistry |
Carbohydrates |
Mechanisms of Reactions |
Proteins / Peptides |
Bioorganic Chemistry
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Nature's Way To Make the Lantibiotics Heather A. Relyea and Wilfred A. van der Donk
This article focuses on one class of antimicrobial compounds, the lantibiotics, and discusses their biosynthetic pathways as well as their molecular mode of action. In the course of the review, the meaning of the terms regio-, chemo-, and stereoselectivity are discussed.
Relyea, Heather A.; van der Donk, Wilfred A. J. Chem. Educ. 2006, 83, 1769.
Applications of Chemistry |
Bioorganic Chemistry |
Biotechnology |
Biosynthesis |
Catalysis |
Drugs / Pharmaceuticals |
Proteins / Peptides
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Using Physical Models of Biomolecular Structures To Teach Concepts of Biochemical Structure and Structure Depiction in the Introductory Chemistry Laboratory Gordon A. Bain, John Yi, Mithra Beikmohamadi, Timothy M. Herman, and Michael A. Patrick
Custom-made physical models of alpha-helices and beta-sheets, the zinc finger moiety, beta-globin, and green fluorescent protein are used to introduce students in first-year chemistry to the primary, secondary, and tertiary structure of proteins.
Bain, Gordon A.; Yi, John; Beikmohamadi, Mithra; Herman, Timothy M.; Patrick, Michael A. J. Chem. Educ. 2006, 83, 1322.
Amino Acids |
Proteins / Peptides |
Molecular Modeling |
Molecular Properties / Structure |
Nucleic Acids / DNA / RNA
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Gifts from Mother Earth—The Good, the Bad, and the Ugly Sabine Heinhorst and Gordon C. Cannon
Recent articles from the journal Nature that deal with good, bad, and ugly gifts from Mother Earth are described.
Heinhorst, Sabine; Cannon, Gordon C. J. Chem. Educ. 2006, 83, 196.
Biosynthesis |
Biotechnology |
Natural Products |
Nutrition |
Plant Chemistry |
Polymerization |
Proteins / Peptides
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Blood-Chemistry Tutorials: Teaching Biological Applications of General Chemistry Material Rachel E. Casiday, Dewey Holten, Richard Krathen, and Regina F. Frey
Four, Web-based tutorials that deal with chemical processes in the blood and provide an integrated biological context for a variety of chemical concepts.
Casiday, Rachel E.; Holten, Dewey; Krathen, Richard; Frey, Regina F. J. Chem. Educ. 2001, 78, 1210.
Applications of Chemistry |
Medicinal Chemistry |
Proteins / Peptides |
Acids / Bases |
Equilibrium |
Molecular Properties / Structure
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A Simple Protein Purification and Folding Experiment for General Chemistry Laboratory Robert Bowen, Richard Hartung, and Yvonne M. Gindt
A simple procedure for the crude purification of a chromoprotein suitable for a general chemistry laboratory. The protein, phycocyanin, is easy to purify and very stable. It contains a chromophore that can serve to report the integrity of the protein structure: the chromoprotein is dark blue when the protein is folded in its native conformation, and it turns a very pale blue when the protein is unfolded or denatured.
Bowen, Robert ; Hartung, Richard; Gindt, Yvonne M. J. Chem. Educ. 2000, 77, 1456.
Noncovalent Interactions |
Photochemistry |
Proteins / Peptides |
UV-Vis Spectroscopy
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Analysis of Iron in Ferritin, the Iron-Storage Protein: A General Chemistry Experiment Maureen J. Donlin, Regina F. Frey, Christopher Putnam, Jody Proctor, and James K. Bashkin
The chemical properties of the iron-storage protein ferritin will be examined in this experiment by quantitating the average amount of iron in a ferritin sample, and observing the kinetics of iron release from the protein core under reducing conditions. Students learn and apply the principles of absorption spectroscopy, redox reactions, and metal chelation to study ferritin.
Maureen J. Donlin, Regina F. Frey, Christopher Putnam, Jody Proctor, and James K. Bashkin. J. Chem. Educ. 1998, 75, 437.
Oxidation / Reduction |
UV-Vis Spectroscopy |
Proteins / Peptides
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Analogical demonstrations Fortman, John J.
By illustrating an analogy with a visual demonstration, a student is aided in both understanding and remembering a lesson.
Fortman, John J. J. Chem. Educ. 1992, 69, 323.
Physical Properties |
Atomic Properties / Structure |
Amino Acids |
Proteins / Peptides |
Acids / Bases
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The catalytic function of enzymes Splittgerber, Allan G.
Review of the structure, function, and factors that influence the action of enzymes.
Splittgerber, Allan G. J. Chem. Educ. 1985, 62, 1008.
Catalysis |
Enzymes |
Mechanisms of Reactions |
Proteins / Peptides |
Molecular Properties / Structure
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Perspectives in biochemistry: Methods for DNA sequencing Wood, Anne T.
Describes how DNA is sequenced.
Wood, Anne T. J. Chem. Educ. 1984, 61, 886.
Proteins / Peptides |
Biotechnology |
Electrophoresis
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The chemical composition of the cell Holum, John R.
A broad outline of the chemical substances that occur in most cells.
Holum, John R. J. Chem. Educ. 1984, 61, 877.
Biological Cells |
Lipids |
Carbohydrates |
Proteins / Peptides
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Isoenzymes Daugherty, N. A.
The separation, identification, and measurement of isoenzymes is an appropriate topic for a special lecture in general chemistry.
Daugherty, N. A. J. Chem. Educ. 1979, 56, 442.
Enzymes |
Proteins / Peptides |
pH |
Electrophoresis |
Separation Science |
Electrochemistry |
Applications of Chemistry
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Amino acid sequence diversity in proteins Blackman, David
The number of unique proteins that can be generated from a small number of amino acids is truly enormous.
Blackman, David J. Chem. Educ. 1977, 54, 170.
Proteins / Peptides |
Amino Acids
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Non-covalent interactions: Key to biological flexibility and specificity Frieden, Earl
Summarizes the types of non-covalent interactions found among biomolecules and how they facilitate the function of antibodies, hormones, and hemoglobin.
Frieden, Earl J. Chem. Educ. 1975, 52, 754.
Noncovalent Interactions |
Hydrogen Bonding |
Water / Water Chemistry |
Proteins / Peptides |
Amino Acids |
Molecular Properties / Structure |
Hormones
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Sulfur compounds. Pollution, health effects, and biological function Leh, F.; Chan, K. M.
Reviews the role of sulfur and its compounds in pollution and adverse health effects as well as biological functions.
Leh, F.; Chan, K. M. J. Chem. Educ. 1973, 50, 246.
Nonmetals |
Proteins / Peptides
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Sickle-cell anemia, hemoglobin solubility and resistance to malaria Martin, David L.; Huheey, James E.
The phenomenon of erythrocytic sickling is of considerable pedagogical usefulness since it provides a bridge of relevance between chemistry and biology.
Martin, David L.; Huheey, James E. J. Chem. Educ. 1972, 49, 177.
Proteins / Peptides |
Medicinal Chemistry |
Applications of Chemistry
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Disposable macromolecular model "kits" Nicholson, Isadore
A brief note suggesting the use of colored pipe cleaners for the construction of three dimensional models of polymers, particularly enzymes and other proteins.
Nicholson, Isadore J. Chem. Educ. 1969, 46, 671.
Molecular Modeling |
Enzymes |
Proteins / Peptides
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VI - Biochemistry in the introductory college chemistry course Sturtevant, Julian M.
To whatever extent one wishes in the introductory chemistry course to stimulate students' interest in the subject, it seems important to include illustrations of the role chemical progress plays in biology.
Sturtevant, Julian M. J. Chem. Educ. 1967, 44, 184.
Enzymes |
Proteins / Peptides |
Bioenergetics
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Ribonucleic acid: The simplest information-transmitting molecule Fraenkel-Conrat, H.
Examines the chemical structure of nucleic acids, chemical modification of RNA and mutagenesis, role of RNA in protein structure, the mechanism of information transfer from RNA to protein, and mutants and coding.
Fraenkel-Conrat, H. J. Chem. Educ. 1963, 40, 216.
Proteins / Peptides
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The geometry of giant molecules Price, Charles C.
The author examines a variety of specific examples of natural and synthetic polymer molecules and describes how their geometric molecular arrangements influence their properties.
Price, Charles C. J. Chem. Educ. 1959, 36, 160.
Molecular Properties / Structure |
Proteins / Peptides |
Carbohydrates
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Schematic models of biochemical polymers Blackwell, R. Quentin
Demonstrates the use of plastic necklace beads to represent polysaccharides, peptides and proteins, and nucleotides.
Blackwell, R. Quentin J. Chem. Educ. 1957, 34, 500.
Molecular Modeling |
Molecular Properties / Structure |
Proteins / Peptides |
Carbohydrates
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Model of the alpha helix configuration in polypeptides Whalen, Thomas A.
The alpha helix configuration in polypeptides is modeled using sheets of ordinary paper.
Whalen, Thomas A. J. Chem. Educ. 1957, 34, 136.
Molecular Modeling |
Molecular Properties / Structure |
Proteins / Peptides
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Potentialities of protein isomerism Asimov, Isaac
The permutations generated by structural isomerism in proteins could be demonstrated more convincingly and realistically if the amino acid compositions of actual proteins were taken into consideration.
Asimov, Isaac J. Chem. Educ. 1954, 31, 125.
Proteins / Peptides |
Molecular Properties / Structure |
Amino Acids |
Constitutional Isomers
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