| Journal Articles: 29 results |
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Real-World Topics: Medicinal Chemistry Arrietta Clauss
Instructors often look for real-world topics that interest students when designing labs and preparing lectures. The chemistry associated with drugs is a fertile area, and the archives of the Journal can be a resource for interesting drug-related activities to enhance student learning.
Clauss, Arrietta. J. Chem. Educ. 2008, 85, 1657.
Enrichment / Review Materials |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Applications of Chemistry
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Calcium Phosphates and Human Beings Sergey V. Dorozhkin
This article describes the general importance of calcium phosphates for human beings. The basic information on the structure and chemical properties of the biologically relevant calcium phosphates is summarized.
Dorozhkin, Sergey V. J. Chem. Educ. 2006, 83, 713.
Applications of Chemistry |
Bioinorganic Chemistry |
Biotechnology |
Materials Science |
Medicinal Chemistry |
Natural Products
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Stoichiometry of Calcium Medicines Gabriel Pinto
Calcium supplements provide an excellent context in which to review most of the core content of general chemistry, namely, stoichiometry, concentration units, hydration of salts, inorganic and organic salts, physiological importance of elements, resonance in ions, geometry of polyatomic ions, and isomerism.
Pinto, Gabriel. J. Chem. Educ. 2005, 82, 1509.
Stoichiometry |
Applications of Chemistry |
Drugs / Pharmaceuticals |
Medicinal Chemistry
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Based on a True Story: Using Movies as Source Material for General Chemistry Reports Mark A. Griep and Marjorie L. Mikasen
Presents a list of one dozen, highly rated movies in which the focus is either a scientist's chemical research or the societal impact of some chemical compound. The method by which two of these movies were used as source material for a written report in a general chemistry course is described.
Griep, Mark A.; Mikasen, Marjorie L. J. Chem. Educ. 2005, 82, 1501.
Medicinal Chemistry |
Women in Chemistry |
Applications of Chemistry |
Drugs / Pharmaceuticals |
Industrial Chemistry |
Nonmajor Courses |
Nuclear / Radiochemistry
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Carbon Dioxide Flooding: A Classroom Case Study Derived from Surgical Practice Robert C. Kerber
The surgical opening in open-heart surgery is often flooded with carbon dioxide gas to avoid air embolisms when the heart is closed and restarted. This practice can be used in chemistry courses to illustrate concepts of gas density, solubility, and acidbase equilibria, including buffering.
Kerber, Robert C. . J. Chem. Educ. 2003, 80, 1437.
Acids / Bases |
Aqueous Solution Chemistry |
Gases |
Medicinal Chemistry |
Nonmajor Courses |
Applications of Chemistry
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Drugs and the Human Body: With Implications for Society, 6th Edition
by Ken Liska David J. A. Schedler
Facts about drug sources, history, action in the body, side effects, interactions, tolerance, abuse potential, dosage, dependency, delivery systems, and alternatives to drug use.
Schedler, David J. A. J. Chem. Educ. 2002, 79, 805.
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Applications of Chemistry
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Modeling the Drug Discovery Process: The Isolation and Biological Testing of Eugenol from Clove Oil William H. Miles and Patricia M. Smiley
Experiment that illustrates the principles of modern drug discovery.
Miles, William H.; Smiley, Patricia M. J. Chem. Educ. 2002, 79, 90.
Acids / Bases |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Natural Products |
Separation Science |
Applications of Chemistry
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Blood-Chemistry Tutorials: Teaching Biological Applications of General Chemistry Material Rachel E. Casiday, Dewey Holten, Richard Krathen, and Regina F. Frey
Four, Web-based tutorials that deal with chemical processes in the blood and provide an integrated biological context for a variety of chemical concepts.
Casiday, Rachel E.; Holten, Dewey; Krathen, Richard; Frey, Regina F. J. Chem. Educ. 2001, 78, 1210.
Applications of Chemistry |
Medicinal Chemistry |
Proteins / Peptides |
Acids / Bases |
Equilibrium |
Molecular Properties / Structure
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Combinatorial Synthesis and Discovery of an Antibiotic Compound. An Experiment Suitable for High School and Undergraduate Laboratories Scott E. Wolkenberg and Andrew I. Su
An experiment designed to introduce students to combinatorial chemistry as applied to drug discovery.
Wolkenberg, Scott E.; Su, Andrew I. J. Chem. Educ. 2001, 78, 784.
Aqueous Solution Chemistry |
Bioorganic Chemistry |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Synthesis |
Combinatorial Chemistry |
Applications of Chemistry
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Discovery and Early Uses of Iodine Louis Rosenfeld
Therapeutic use of iodine, particularly in prevention and treatment of goiter.
Rosenfeld, Louis. J. Chem. Educ. 2000, 77, 984.
Medicinal Chemistry |
Descriptive Chemistry |
Applications of Chemistry
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Henry's Law and Noisy Knuckles Doris R. Kimbrough
Presented here is the application of Henry's law to the noise associated with "cracking" knuckles. Gases dissolved in the synovial fluid in joints rapidly come out of solution as the joint is stretched and pressure is decreased. This "cavitation" produces a characteristic noise.
Kimbrough, Doris R. J. Chem. Educ. 1999, 76, 1509.
Gases |
Solutions / Solvents |
Applications of Chemistry |
Medicinal Chemistry
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The Art and Science of Organic and Natural Products Synthesis K. C. Nicolaou, E. J. Sorensen, and N. Winssinger
In this article, the history of the art and science of organic and natural products synthesis is briefly reviewed and the state of the art is discussed. The impact of this discipline on biology and medicine is amply demonstrated with examples, and projections for future developments in the field are made.
Nicolaou, K. C.; Sorensen, E. J.; Winssinger, N. J. Chem. Educ. 1998, 75, 1225.
Natural Products |
Synthesis |
Medicinal Chemistry |
Applications of Chemistry |
Drugs / Pharmaceuticals
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Vanillin (the author replies) Hocking, Martin
Additional information regarding salicylic acid.
Hocking, Martin J. Chem. Educ. 1998, 75, 1203.
Aldehydes / Ketones |
Applications of Chemistry |
Medicinal Chemistry |
Molecular Properties / Structure
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Vanillin Calloway, Dean
Incorrect structural formula for methyl salicylate.
Calloway, Dean J. Chem. Educ. 1998, 75, 1203.
Medicinal Chemistry |
Applications of Chemistry |
Aldehydes / Ketones |
Molecular Properties / Structure
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Letters
Incorrect structural formula for methyl salicylate.
J. Chem. Educ. 1998, 75, 1203.
Medicinal Chemistry |
Applications of Chemistry |
Aldehydes / Ketones |
Molecular Properties / Structure
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Teaching the skills of science - gold and anemia Mattson, William
A student poses a question that leads to classroom inquiry: Why does gold rubbed on the face of an anemic person leave a dark mark?
Mattson, William J. Chem. Educ. 1988, 65, 1000.
Bioinorganic Chemistry |
Medicinal Chemistry |
Applications of Chemistry
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Consumer applications of chemical principles: Drugs Hill, John W.; Jones, Susan M.
Acid-base chemistry of drugs (nicotine, cocaine, and aspirin), general anesthesia (nitrous oxide, enflurane, isoflurane, halothane), local anesthetics (procaine, lidocaine, cocaine), and intravenous anesthetics (thiopental, ketamine hydrochloride, phencyclidine).
Hill, John W.; Jones, Susan M. J. Chem. Educ. 1985, 62, 328.
Consumer Chemistry |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Acids / Bases |
Applications of Chemistry
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Chemistry instruction using evening news video tape segments Greenberg, Fred G.
Evening newscasts often provide current, dramatic, and meaningful applications of basic chemical principles.
Greenberg, Fred G. J. Chem. Educ. 1985, 62, 227.
Medicinal Chemistry |
Applications of Chemistry
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Magical sand Smith, Douglas D.
Smith, Douglas D. J. Chem. Educ. 1980, 57, 363.
Applications of Chemistry |
Medicinal Chemistry
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Drugs in the chemistry laboratory: The conversion of acetaminophen into phenacetin Volker, Eugene J.; Pride, Ernest; Hough, Charles
The phenolic alcohol group of acetaminophen is alkylated with ethyl iodide using the basic catalyst K2CO3.
Volker, Eugene J.; Pride, Ernest; Hough, Charles J. Chem. Educ. 1979, 56, 831.
Nonmajor Courses |
Applications of Chemistry |
Medicinal Chemistry |
Drugs / Pharmaceuticals |
Synthesis |
Catalysis |
Phenols |
Alcohols
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Some biochemistry of sedatives J. Chem. Educ. Staff
Antianxiety agents / sleep reducers, the discovery of sedatives and their chemistry, and biological responses to sedatives.
J. Chem. Educ. Staff J. Chem. Educ. 1979, 56, 402.
Drugs / Pharmaceuticals |
Applications of Chemistry |
Medicinal Chemistry
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Medicinal chemistry of aspirin and related drugs J. Chem. Educ. Staff
Nonprescription analgesics, the discovery of aspirin, pain and analgesic activity, inflammation and the role of chemical agents, fever and its reduction, aspirin in stroke prevention, and toxicity and side effects.
J. Chem. Educ. Staff J. Chem. Educ. 1979, 56, 331.
Applications of Chemistry |
Medicinal Chemistry |
Drugs / Pharmaceuticals |
Toxicology
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The effects of HCl and aspirin on the stomach: An equilibrium review DeLorenzo, Ronald
The chemical effect and medical implications of taking aspirin.
DeLorenzo, Ronald J. Chem. Educ. 1977, 54, 306.
Equilibrium |
Acids / Bases |
pH |
Drugs / Pharmaceuticals |
Medicinal Chemistry |
Applications of Chemistry
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Questions [and] Answers Campbell, J. A.
290-297. Eight questions regarding practical applications of chemistry, primarily in the medical field, and their answers.
Campbell, J. A. J. Chem. Educ. 1977, 54, 247.
Toxicology |
Equilibrium |
Metabolism |
Medicinal Chemistry |
Applications of Chemistry |
Enrichment / Review Materials
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Questions [and] Answers Campbell, J. A.
284-289. Six questions and their answers on practical applications of chemistry.
Campbell, J. A. J. Chem. Educ. 1977, 54, 161.
Medicinal Chemistry |
Enzymes |
Nuclear / Radiochemistry |
Drugs / Pharmaceuticals |
Applications of Chemistry |
Enrichment / Review Materials
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Minicourses in chemistry Lygre, D. G.; Hasbrouck, R. W.; Gaines, R. D.; Duncan, L. C.; Habib, H. S.; Meany, J. E.; Newschwander, W. W.
Briefly describes a variety of minicourses designed to acquaint students with practical applications of chemistry in everyday experiences.
Lygre, D. G.; Hasbrouck, R. W.; Gaines, R. D.; Duncan, L. C.; Habib, H. S.; Meany, J. E.; Newschwander, W. W. J. Chem. Educ. 1975, 52, 735.
Consumer Chemistry |
Medicinal Chemistry |
Nuclear / Radiochemistry |
Plant Chemistry |
Agricultural Chemistry |
Applications of Chemistry |
Food Science
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A new chemistry program for nursing and allied health students Stanitski, Conrad L.; Sears, Curtis T., Jr.
Outlines and discusses the topics considered in a chemistry program for nursing and allied health students.
Stanitski, Conrad L.; Sears, Curtis T., Jr. J. Chem. Educ. 1975, 52, 226.
Nonmajor Courses |
Applications of Chemistry |
Medicinal Chemistry |
Oxidation / Reduction |
Catalysis |
Acids / Bases |
pH |
Metabolism |
Drugs / Pharmaceuticals
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Pain: A chemical explanation Plumb, Robert C.; Lindahl, Olov
In sensing pain the nervous system acts like a pH meter.
Plumb, Robert C.; Lindahl, Olov J. Chem. Educ. 1972, 49, 179.
pH |
Acids / Bases |
Applications of Chemistry |
Medicinal Chemistry
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Sickle-cell anemia, hemoglobin solubility and resistance to malaria Martin, David L.; Huheey, James E.
The phenomenon of erythrocytic sickling is of considerable pedagogical usefulness since it provides a bridge of relevance between chemistry and biology.
Martin, David L.; Huheey, James E. J. Chem. Educ. 1972, 49, 177.
Proteins / Peptides |
Medicinal Chemistry |
Applications of Chemistry
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