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Molecules and Medicine (E. J. Corey, Barbara Czakó, and László Kürti) Robert E. Buntrock Looking for a book on common drugs and pharmaceuticals? On diseases and medical conditions? On pharmacology? In addition, do you need some background in chemistry to handle all of this information? If you want all of this, and in addition want it under one cover, then this is the book for you. Buntrock, Robert E. J. Chem. Educ. 2008, 85, 1495.
Bioorganic Chemistry |
Drugs / Pharmaceuticals |
Molecular Properties / Structure |
Proteins / Peptides |
Synthesis |
Toxicology
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OMLeT—An Alternative Approach to Learning Metabolism: Glycolysis and the TCA Cycle as an Example Charles M. Stevens, Dylan M. Silver, Brad Behm, Raymond J. Turner, and Michael G. Surette Using PHP Hypertext Preprocessor scripting, the dynamic OMLeT (Online Metabolism Learning Tool) Web site is geared towards different learning styles and allows the student to process metabolic pathways (glycolysis and TCA cycle) via a user-defined approach. Stevens, Charles M.; Silver, Dylan M.; Behm, Brad; Turner, Raymond J.; Surette, Michael G. J. Chem. Educ. 2007, 84, 2024.
Bioenergetics |
Enzymes |
Learning Theories |
Metabolism |
Proteins / Peptides
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Illustrating the Concepts of Isotopes and Mass Spectrometry in Introductory Courses: A MALDI-TOF Mass Spectrometry Laboratory Experiment Nancy Carter Dopke and Timothy Neal Lovett This article describes a matrix-assisted laser desorption/ionization (MALDI) mass spectrometry experiment in which students prepare peptide samples for mass analysis and then collect and analyze mass spectral data. The lab provides hands-on experience with research instrumentation and reinforces the concepts of isotopes, molecular masses, and molecular formulas. Dopke, Nancy Carter; Lovett, Timothy Neal. J. Chem. Educ. 2007, 84, 1968.
Isotopes |
Mass Spectrometry |
Proteins / Peptides
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The A1c Blood Test: An Illustration of Principles from General and Organic Chemistry Robert C. Kerber The glycated hemoglobin blood test is a key measure of the effectiveness of glucose control in diabetics. The chemistry of glucose in the bloodstream, which underlies the test and its impact, provides an illustration of the importance of chemical equilibrium and kinetics to a major health problem. Kerber, Robert C. . J. Chem. Educ. 2007, 84, 1541.
Applications of Chemistry |
Bioinorganic Chemistry |
Carbohydrates |
Mechanisms of Reactions |
Proteins / Peptides |
Bioorganic Chemistry
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A Colorimetric Analysis Experiment Not Requiring a Spectrophotometer: Quantitative Determination of Albumin in Powdered Egg White Amanda K. Charlton, Richard S. Sevcik, Dorie A. Tucker, and Linda D. Schultz Albumin in powdered egg white is reacted with bromophenol blue, and the resulting blue color is compared to that formed by an albumin standard using a visual comparator method. Charlton, Amanda K.; Sevcik, Richard S.; Tucker, Dorie A.; Schultz, Linda D. J. Chem. Educ. 2007, 84, 826.
Bioanalytical Chemistry |
Dyes / Pigments |
Proteins / Peptides |
Quantitative Analysis
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Nature's Way To Make the Lantibiotics Heather A. Relyea and Wilfred A. van der Donk This article focuses on one class of antimicrobial compounds, the lantibiotics, and discusses their biosynthetic pathways as well as their molecular mode of action. In the course of the review, the meaning of the terms regio-, chemo-, and stereoselectivity are discussed. Relyea, Heather A.; van der Donk, Wilfred A. J. Chem. Educ. 2006, 83, 1769.
Applications of Chemistry |
Bioorganic Chemistry |
Biotechnology |
Biosynthesis |
Catalysis |
Drugs / Pharmaceuticals |
Proteins / Peptides
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Using Physical Models of Biomolecular Structures To Teach Concepts of Biochemical Structure and Structure Depiction in the Introductory Chemistry Laboratory Gordon A. Bain, John Yi, Mithra Beikmohamadi, Timothy M. Herman, and Michael A. Patrick Custom-made physical models of alpha-helices and beta-sheets, the zinc finger moiety, beta-globin, and green fluorescent protein are used to introduce students in first-year chemistry to the primary, secondary, and tertiary structure of proteins. Bain, Gordon A.; Yi, John; Beikmohamadi, Mithra; Herman, Timothy M.; Patrick, Michael A. J. Chem. Educ. 2006, 83, 1322.
Amino Acids |
Proteins / Peptides |
Molecular Modeling |
Molecular Properties / Structure |
Nucleic Acids / DNA / RNA
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Amino Acids William F. Coleman The Featured Molecules this month are the 20 standard alpha-amino acids found in proteins. The molecules are presented in two formats, the neutral form and the ionized form found in solution at physiologic pH. Coleman, William F. J. Chem. Educ. 2006, 83, 1103.
Amino Acids |
Proteins / Peptides |
Molecular Properties / Structure |
Molecular Modeling |
Molecular Mechanics / Dynamics
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Gifts from Mother Earth—The Good, the Bad, and the Ugly Sabine Heinhorst and Gordon C. Cannon Recent articles from the journal Nature that deal with good, bad, and ugly gifts from Mother Earth are described. Heinhorst, Sabine; Cannon, Gordon C. J. Chem. Educ. 2006, 83, 196.
Biosynthesis |
Biotechnology |
Natural Products |
Nutrition |
Plant Chemistry |
Polymerization |
Proteins / Peptides
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Amino Acid Complementarity: A Biochemical Exemplar of Stoichiometry for General and Health Sciences Chemistry Ed Vitz Calculations demonstrating amino acid complementarity are presented as an interesting application of stoichiometry. Food proteins are said to have complementary amino acids when the proteins combine to provide amino acids in the proper stoichiometric ratios to synthesize human protein. Implications for vegetarian diet, efficiency of food production, and diet adaptations in various cultures are explored briefly. Vitz, Ed. J. Chem. Educ. 2005, 82, 1013.
Amino Acids |
Proteins / Peptides |
Stoichiometry |
Food Science
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A Supramolecular Approach to Medicinal Chemistry: Medicine Beyond the Molecule David K. Smith This article emphasizes a conceptual view of medicinal chemistry, which has important implications for the future, as the supramolecular approach to medicinal-chemistry products outlined here is rapidly allowing nanotechnology to converge with medicine. In particular, this article discusses recent developments including the rational design of drugs such as Relenza and Tamiflu, the mode of action of vancomycin, and the mechanism by which bacteria develop resistance, drug delivery using cyclodextrins, and the importance of supramolecular chemistry in understanding protein aggregation diseases such as Alzheimer's and CreutzfieldJacob. Smith, David K. J. Chem. Educ. 2005, 82, 393.
Drugs / Pharmaceuticals |
Noncovalent Interactions |
Medicinal Chemistry |
Nanotechnology |
Proteins / Peptides
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A Modular Laser Apparatus for Polarimetry, Nephelometry, and Fluorimetry in General Chemistry Scott A. Darveau, Jessica Mueller, April Vaverka, Cheri Barta, Anthony Fitch, Jessica Jurzenski, and Yvonne Gindt We present an apparatus suitable for multiple uses in the general chemistry laboratory including polarimetry, fluorescence, and nephelometry. The open design of the instrument also decreases the chance that students will contract the "black-box syndrome" that seems to develop when using instruments that only provide the final data in an experiment without showing how the measurements are obtained. Darveau, Scott A.; Mueller, Jessica; Vaverka, April; Barta, Cheri; Fitch, Anthony; Jurzenski, Jessica; Gindt, Yvonne. J. Chem. Educ. 2004, 81, 401.
Fluorescence Spectroscopy |
Kinetics |
Laboratory Equipment / Apparatus |
Lasers |
Spectroscopy |
Proteins / Peptides |
Water / Water Chemistry
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A "Polypeptide Demonstrator" Addison Ault I have used a telephone Handset Coil Cord as a simple and convenient model for the structure of a polypeptide. Ault, Addison. J. Chem. Educ. 2004, 81, 196.
Proteins / Peptides |
Molecular Modeling |
Molecular Properties / Structure
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Mass Spectra JCE Editorial Staff Activity in which students solve puzzles analogous to finding the amino acid sequence of a peptide using mass spectrometry. JCE Editorial Staff. J. Chem. Educ. 2003, 80, 176A.
Amino Acids |
Mass Spectrometry |
Proteins / Peptides
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Some Like It Cold: A Computer-Based Laboratory Introduction to Sequence and Tertiary Structure Comparison of Cold-Adapted Lactate Dehydrogenases Using Bioinformatics Tools M. Sue Lowery and Leigh A. Plesniak Students download sequences and structures from appropriate databases, create sequence alignments, and carry out molecular modeling exercises, and then form hypotheses about the mechanism of biochemical adaptation for function and stability. This laboratory is appropriate for biochemistry and molecular biology laboratory courses, special topics, and advanced biochemistry lecture courses, and can be adapted for honors high school programs. Lowery, M. Sue; Plesniak, Leigh A. J. Chem. Educ. 2003, 80, 1300.
Enzymes |
Molecular Modeling |
Proteins / Peptides |
Molecular Properties / Structure
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Simple Recipes for Prebiotic Soup: A High School or Undergraduate Chemistry Laboratory Marisol Martinez-Meeler, Nika Aljinovic, and Dorothy Swain Replicating Stanley Miller's prebiotic soup experiment for introductory chemistry; includes experimental apparatus and analysis of the products. Martinez-Meeler, Marisol; Aljinovic, Nika; Swain, Dorothy. J. Chem. Educ. 2003, 80, 665.
Amino Acids |
Aqueous Solution Chemistry |
Chromatography |
Electrochemistry |
Proteins / Peptides |
Synthesis |
Applications of Chemistry
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Introducing Freshmen Students to the Practice of Solid-Phase Synthesis Alpay Taralp, Can Hulusi Türkseven, Atilla Özgür Çakmak, and Ömer Çengel Procedure to introduce freshmen to the principles and practice of solid-phase (peptide) synthesis. Taralp, Alpay; Türkseven, Can Hulusi; Çakmak, Atilla Özgür; Çengel, Ömer. J. Chem. Educ. 2002, 79, 87.
Biotechnology |
Enzymes |
Synthesis |
Proteins / Peptides |
Undergraduate Research
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Factors Affecting Reaction Kinetics of Glucose Oxidase Kristin A. Johnson Demonstration based on a biochemical kinetics experiment in which the rate of reaction varies with the enzyme concentration, substrate concentration, substrate used in the reaction, and temperature. Johnson, Kristin A. J. Chem. Educ. 2002, 79, 74.
Enzymes |
Kinetics |
Proteins / Peptides |
Carbohydrates |
Catalysis |
Rate Law
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Blood-Chemistry Tutorials: Teaching Biological Applications of General Chemistry Material Rachel E. Casiday, Dewey Holten, Richard Krathen, and Regina F. Frey Four, Web-based tutorials that deal with chemical processes in the blood and provide an integrated biological context for a variety of chemical concepts. Casiday, Rachel E.; Holten, Dewey; Krathen, Richard; Frey, Regina F. J. Chem. Educ. 2001, 78, 1210.
Applications of Chemistry |
Medicinal Chemistry |
Proteins / Peptides |
Acids / Bases |
Equilibrium |
Molecular Properties / Structure
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Protein Structure Wordsearch Terry L. Helser Puzzle with 37 names, terms, prefixes, and acronyms that describe protein structure. Helser, Terry L. J. Chem. Educ. 2001, 78, 474.
Proteins / Peptides |
Nomenclature / Units / Symbols |
Molecular Properties / Structure
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The Chemical Adventures of Sherlock Holmes: The Shroud of Spartacus Thomas G. Waddell and Thomas R. Rybolt A chemical mystery featuring Sherlock Holmes and Dr. Watson. Waddell, Thomas G.; Rybolt, Thomas R. J. Chem. Educ. 2001, 78, 470.
Enrichment / Review Materials |
Forensic Chemistry |
Proteins / Peptides |
Quantitative Analysis
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A Simple Protein Purification and Folding Experiment for General Chemistry Laboratory Robert Bowen, Richard Hartung, and Yvonne M. Gindt A simple procedure for the crude purification of a chromoprotein suitable for a general chemistry laboratory. The protein, phycocyanin, is easy to purify and very stable. It contains a chromophore that can serve to report the integrity of the protein structure: the chromoprotein is dark blue when the protein is folded in its native conformation, and it turns a very pale blue when the protein is unfolded or denatured. Bowen, Robert ; Hartung, Richard; Gindt, Yvonne M. J. Chem. Educ. 2000, 77, 1456.
Noncovalent Interactions |
Photochemistry |
Proteins / Peptides |
UV-Vis Spectroscopy
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A Simple Method for Demonstrating Enzyme Kinetics Using Catalase from Beef Liver Extract Kristin A. Johnson A simple visual method of demonstrating enzyme kinetics using beef liver catalase. Filter paper is saturated with beef liver extract and placed into a solution of hydrogen peroxide. The catalase in the extract decomposes the hydrogen peroxide to water and oxygen. Oxygen forms on the filter paper, and the filter paper rises to the top of the beaker. Catalase activity is measured by timing the rise of the enzyme-soaked filter paper to the top of beakers containing different concentrations of hydrogen peroxide. Johnson, A. Kristin. J. Chem. Educ. 2000, 77, 1451.
Enzymes |
Kinetics |
Proteins / Peptides |
Reactions
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Soup or Salad? Investigating the Action of Enzymes in Fruit on Gelatin Erica Jacobsen Some fruits contain proteases, a group of enzymes that catalyze the cleavage of peptide linkages in proteins. This can have an undesired effect in a gelatin salad containing fruit, because proteases in the fruit can cleave the proteins that make up the structure of gelatin so that it will not set. Jacobsen, Erica. J. Chem. Educ. 1999, 76, 624A.
Enzymes |
Proteins / Peptides
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Analysis of Iron in Ferritin, the Iron-Storage Protein: A General Chemistry Experiment Maureen J. Donlin, Regina F. Frey, Christopher Putnam, Jody Proctor, and James K. Bashkin The chemical properties of the iron-storage protein ferritin will be examined in this experiment by quantitating the average amount of iron in a ferritin sample, and observing the kinetics of iron release from the protein core under reducing conditions. Students learn and apply the principles of absorption spectroscopy, redox reactions, and metal chelation to study ferritin. Maureen J. Donlin, Regina F. Frey, Christopher Putnam, Jody Proctor, and James K. Bashkin. J. Chem. Educ. 1998, 75, 437.
Oxidation / Reduction |
UV-Vis Spectroscopy |
Proteins / Peptides
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Showing Food Foams Properties with Common Dairy Foods Carlos Bravo-Diaz and Elisa Gonzalez-Romero Some easy to carry, inexpensive and safe experiments developed using familiar kitchen materials related with egg foams. Eggs's properties are not only limited to prepare excellent and delicious emulsions like mayonnaise but also makes excellent foams, increasing their volume significantly in two primary ways. Bravo-Diaz, Carlos; Gonzalez-Romero, Elisa. J. Chem. Educ. 1997, 74, 1133.
Learning Theories |
Food Science |
Proteins / Peptides |
Applications of Chemistry
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A Simulated Growth Hormone Analysis Mary Harris Growth hormone is a drug that is sometimes abused by amateur or professional athletes for performance-enhancement. This laboratory is a semi-microscale simulation analysis of a sample of "urine" to detect proteins of two very different molecular weights. Harris, Mary. J. Chem. Educ. 1996, 73, 735.
Hormones |
Proteins / Peptides |
Separation Science |
Microscale Lab |
Drugs / Pharmaceuticals |
Qualitative Analysis
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Use of Tangle Links To Show Globular Protein Structure Marino, Francis Using Tangle Links (a child's toy) to model the primary, secondary, tertiary, and quaternary structure of proteins. Marino, Francis J. Chem. Educ. 1994, 71, 741.
Proteins / Peptides |
Molecular Modeling
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An Attack on the AIDS Virus: Inhibition of the HIV-1 Protease. New Drug Development Based on the Structure and Activity of the Protease and its Role in the Replication and Maturation of the Virus Volker, Eugene J. Article shows how research into the biochemistry of HIV may lead to a method for controlling its growth and maturation. This research illustrates some basic enzyme chemistry and holds student appeal due to the tie into current affairs. Volker, Eugene J. J. Chem. Educ. 1993, 70, 3.
Bioorganic Chemistry |
Proteins / Peptides |
Medicinal Chemistry |
Molecular Biology
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Monitoring self-association of a hydrophobic peptide with high performance liquid chromatography: An undergraduate kinetic experiment using the antibiotic gramicidin A Braco, Lorenzo; Ba, M. Carmen; Abad, Concepcin The authors propose a kinetic experiment that uses high performance liquid chromatography to determine the rate and equilibrium constants in a very simple manner, and separate the molecular species under study. Braco, Lorenzo; Ba, M. Carmen; Abad, Concepcin J. Chem. Educ. 1992, 69, A113.
HPLC |
Kinetics |
Proteins / Peptides |
Rate Law |
Equilibrium
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Analogical demonstrations Fortman, John J. By illustrating an analogy with a visual demonstration, a student is aided in both understanding and remembering a lesson. Fortman, John J. J. Chem. Educ. 1992, 69, 323.
Physical Properties |
Atomic Properties / Structure |
Amino Acids |
Proteins / Peptides |
Acids / Bases
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A less hazardous chromic acid substitute for cleaning glassware Manske, Paul M.; Stimpfel, Teresa M.; Gershey, Edward L. Evaluation of several common cleaning solutions for their ability to remove known amounts of baked-on lipid or protein from glassware. Manske, Paul M.; Stimpfel, Teresa M.; Gershey, Edward L. J. Chem. Educ. 1990, 67, A280.
Laboratory Management |
Lipids |
Proteins / Peptides
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Biochemistry laboratory for the freshman chemistry curriculum Falk, Peter M. Intended to introduce students to two important biochemical principles: the study of biomolecules and metabolism. Falk, Peter M. J. Chem. Educ. 1989, 66, 944.
Metabolism |
Carbohydrates |
Lipids |
Proteins / Peptides |
Plant Chemistry
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Lecture demonstrations for organic/ biochemistry allied health courses Deavor, James P. Simple demonstrations on enantiomeric pairs and protein structure. Deavor, James P. J. Chem. Educ. 1988, 65, 622.
Enantiomers |
Chirality / Optical Activity |
Proteins / Peptides |
Nonmajor Courses |
Amino Acids
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Chemistry of polymers, proteins, and nucleic acids: A short course on macromolecules for secondary schools Lulav, Ilan; Samuel, David Topics considered in a macromolecular chemistry unit for advanced high school chemistry students. Lulav, Ilan; Samuel, David J. Chem. Educ. 1985, 62, 1075.
Polymerization |
Proteins / Peptides
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The catalytic function of enzymes Splittgerber, Allan G. Review of the structure, function, and factors that influence the action of enzymes. Splittgerber, Allan G. J. Chem. Educ. 1985, 62, 1008.
Catalysis |
Enzymes |
Mechanisms of Reactions |
Proteins / Peptides |
Molecular Properties / Structure
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Nutrition and problem solving: Food for thought Denio, Allen A.; Bennett, Charles R. Calculating the number of Calories, carbohydrates, protein, and fat per dollar of various foods. Denio, Allen A.; Bennett, Charles R. J. Chem. Educ. 1984, 61, 1076.
Nutrition |
Carbohydrates |
Proteins / Peptides |
Lipids |
Fatty Acids
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Perspectives in biochemistry: Methods for DNA sequencing Wood, Anne T. Describes how DNA is sequenced. Wood, Anne T. J. Chem. Educ. 1984, 61, 886.
Proteins / Peptides |
Biotechnology |
Electrophoresis
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The chemical composition of the cell Holum, John R. A broad outline of the chemical substances that occur in most cells. Holum, John R. J. Chem. Educ. 1984, 61, 877.
Biological Cells |
Lipids |
Carbohydrates |
Proteins / Peptides
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Lemon meringue pie Smith, Douglas D. The chemistry and physics of lemon meringue pie. Smith, Douglas D. J. Chem. Educ. 1982, 59, 60.
Gases |
Ionic Bonding |
Hydrogen Bonding |
Proteins / Peptides
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Protein denaturation: A physical chemistry project lab Pickering, Miles; Crabtree, Robert H. This experiment links physical chemistry with biology and can be done with in advanced freshman course. Pickering, Miles; Crabtree, Robert H. J. Chem. Educ. 1981, 58, 513.
Proteins / Peptides |
Biophysical Chemistry |
Molecular Properties / Structure
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Isoenzymes Daugherty, N. A. The separation, identification, and measurement of isoenzymes is an appropriate topic for a special lecture in general chemistry. Daugherty, N. A. J. Chem. Educ. 1979, 56, 442.
Enzymes |
Proteins / Peptides |
pH |
Electrophoresis |
Separation Science |
Electrochemistry |
Applications of Chemistry
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Compact Compacts Huebner, Jay S.; Shiflett, R. B.; Blanck, Harvey F. A collection of three suggestions regarding demonstrating the oxidation of hydrocarbons and the primary, secondary, and tertiary structure of proteins and the first law of thermodynamics as applied to air conditioning. Huebner, Jay S.; Shiflett, R. B.; Blanck, Harvey F. J. Chem. Educ. 1979, 56, 389.
Oxidation / Reduction |
Alkanes / Cycloalkanes |
Molecular Properties / Structure |
Proteins / Peptides |
Thermodynamics
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Compact compact Nelson, Gregory V. Using a cardboard mailing tube to demonstrate the rigidity of the folding pattern and the flexibility of a non-helical region in a protein. Nelson, Gregory V. J. Chem. Educ. 1977, 54, 578.
Molecular Modeling |
Molecular Properties / Structure |
Proteins / Peptides
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Molecular membrane model Huebner, J. S. Making a model of a lipid bilayer using polystyrene balls and pipe cleaners. Huebner, J. S. J. Chem. Educ. 1977, 54, 171.
Membranes |
Lipids |
Molecular Modeling |
Proteins / Peptides |
Dyes / Pigments
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Amino acid sequence diversity in proteins Blackman, David The number of unique proteins that can be generated from a small number of amino acids is truly enormous. Blackman, David J. Chem. Educ. 1977, 54, 170.
Proteins / Peptides |
Amino Acids
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Non-covalent interactions: Key to biological flexibility and specificity Frieden, Earl Summarizes the types of non-covalent interactions found among biomolecules and how they facilitate the function of antibodies, hormones, and hemoglobin. Frieden, Earl J. Chem. Educ. 1975, 52, 754.
Noncovalent Interactions |
Hydrogen Bonding |
Water / Water Chemistry |
Proteins / Peptides |
Amino Acids |
Molecular Properties / Structure |
Hormones
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Sulfur compounds. Pollution, health effects, and biological function Leh, F.; Chan, K. M. Reviews the role of sulfur and its compounds in pollution and adverse health effects as well as biological functions. Leh, F.; Chan, K. M. J. Chem. Educ. 1973, 50, 246.
Nonmetals |
Proteins / Peptides
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Questions [and] Answers Campbell, J. A. Five questions requiring an application of chemical principles and their solutions. Campbell, J. A. J. Chem. Educ. 1973, 50, 128.
Enrichment / Review Materials |
Proteins / Peptides |
pH |
Carbohydrates |
Molecular Properties / Structure
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The chlorophyll cat Hardcastle, J. E. A short poem and cartoon representation of the chlorophyll structure. Hardcastle, J. E. J. Chem. Educ. 1972, 49, 364.
Plant Chemistry |
Photosynthesis |
Molecular Properties / Structure |
Proteins / Peptides
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Questions [and] Answers Campbell, J. A. Five questions requiring an application of basic chemical principles. Campbell, J. A. J. Chem. Educ. 1972, 49, 269.
Enrichment / Review Materials |
Agricultural Chemistry |
Metabolism |
Calorimetry / Thermochemistry |
Proteins / Peptides
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Sickle-cell anemia, hemoglobin solubility and resistance to malaria Martin, David L.; Huheey, James E. The phenomenon of erythrocytic sickling is of considerable pedagogical usefulness since it provides a bridge of relevance between chemistry and biology. Martin, David L.; Huheey, James E. J. Chem. Educ. 1972, 49, 177.
Proteins / Peptides |
Medicinal Chemistry |
Applications of Chemistry
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Simple method for demonstrating an enzymatic reaction Tang, Chung-Shih Uses taste sensations of papaya seeds under varying conditions to demonstrate an enzymatic reaction. Tang, Chung-Shih J. Chem. Educ. 1970, 47, 692.
Enzymes |
Proteins / Peptides |
Food Science |
Reactions |
Consumer Chemistry |
Applications of Chemistry
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Hydrogen sulfide under any other name still smells. A poisonous story Brasted, Robert C. The chemistry of hydrogen sulfide affords an excellent opportunity to integrate descriptive inorganic and coordination chemistry with biochemistry. Brasted, Robert C. J. Chem. Educ. 1970, 47, 574.
Descriptive Chemistry |
Molecular Properties / Structure |
Coordination Compounds |
Enzymes |
Proteins / Peptides
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Disposable macromolecular model "kits" Nicholson, Isadore A brief note suggesting the use of colored pipe cleaners for the construction of three dimensional models of polymers, particularly enzymes and other proteins. Nicholson, Isadore J. Chem. Educ. 1969, 46, 671.
Molecular Modeling |
Enzymes |
Proteins / Peptides
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Disc electrophoresis Brewer, John M.; Ashworth, Raymond B. Describes the procedures involved in separating proteins or nucleic acids through disc electrophoresis. Brewer, John M.; Ashworth, Raymond B. J. Chem. Educ. 1969, 46, 41.
Electrochemistry |
Electrophoresis |
Proteins / Peptides |
Separation Science
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Simple construction to determine protein molecular weights by the osmotic pressure method Candlish, John K. This short note presents a simple device to determine protein molecular weights through osmotic pressure. Candlish, John K. J. Chem. Educ. 1968, 45, 93.
Molecular Properties / Structure |
Proteins / Peptides |
Physical Properties
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The use of talc as a tlc adsorbent Walsh, Brother Joseph M. Describes the use of talc as a thin layer chromatography adsorbent, particularly with respect to the separation of flavonoids, sugars, and proteins. Walsh, Brother Joseph M. J. Chem. Educ. 1967, 44, 294.
Thin Layer Chromatography |
Chromatography |
Separation Science |
Proteins / Peptides |
Carbohydrates
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VI - Biochemistry in the introductory college chemistry course Sturtevant, Julian M. To whatever extent one wishes in the introductory chemistry course to stimulate students' interest in the subject, it seems important to include illustrations of the role chemical progress plays in biology. Sturtevant, Julian M. J. Chem. Educ. 1967, 44, 184.
Enzymes |
Proteins / Peptides |
Bioenergetics
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Ribonucleic acid: The simplest information-transmitting molecule Fraenkel-Conrat, H. Examines the chemical structure of nucleic acids, chemical modification of RNA and mutagenesis, role of RNA in protein structure, the mechanism of information transfer from RNA to protein, and mutants and coding. Fraenkel-Conrat, H. J. Chem. Educ. 1963, 40, 216.
Proteins / Peptides
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Student experiment with filter paper electrophoresis Garvin, James E. The effect of electrical charge in determining some of the properties of amino acids and proteins can be simply and convincingly demonstrated to the student by means of filter paper electrophoresis. Garvin, James E. J. Chem. Educ. 1961, 38, 36.
Separation Science |
Electrophoresis |
Amino Acids |
Proteins / Peptides |
Electrochemistry
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The geometry of giant molecules Price, Charles C. The author examines a variety of specific examples of natural and synthetic polymer molecules and describes how their geometric molecular arrangements influence their properties. Price, Charles C. J. Chem. Educ. 1959, 36, 160.
Molecular Properties / Structure |
Proteins / Peptides |
Carbohydrates
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Schematic models of biochemical polymers Blackwell, R. Quentin Demonstrates the use of plastic necklace beads to represent polysaccharides, peptides and proteins, and nucleotides. Blackwell, R. Quentin J. Chem. Educ. 1957, 34, 500.
Molecular Modeling |
Molecular Properties / Structure |
Proteins / Peptides |
Carbohydrates
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Model of the alpha helix configuration in polypeptides Whalen, Thomas A. The alpha helix configuration in polypeptides is modeled using sheets of ordinary paper. Whalen, Thomas A. J. Chem. Educ. 1957, 34, 136.
Molecular Modeling |
Molecular Properties / Structure |
Proteins / Peptides
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Potentialities of protein isomerism Asimov, Isaac The permutations generated by structural isomerism in proteins could be demonstrated more convincingly and realistically if the amino acid compositions of actual proteins were taken into consideration. Asimov, Isaac J. Chem. Educ. 1954, 31, 125.
Proteins / Peptides |
Molecular Properties / Structure |
Amino Acids |
Constitutional Isomers
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