Enzyme Activity as a Function of pH©
Paul Krause
Department of Chemistry
University of Central Arkansas
Conway, AK 72035
United States
mail to: paulk@mail.uca.edu



Abstract
This matched pair of documents provide an introduction to the role of pH in the regulation of enzyme activity. In the EnzymeTutorial document the full exercise is developed. This document contains all the equations and graphs for students to use to study the role of pH in enzyme kinetics. Students will also learn some of the skills required for further use of the Mathcad software. The EnzymeExercise document is a twin of the tutorial document. In the Exercise document all equations are omitted so that students can develop these interactively. This provides for a richer more intense learning experience that fits with modern pedagogy. The Exercise document is also ideal for display during lecture where, with the aid of a computer projection system, the ideas can be developed interactively with the class as a whole. The documents come with ample student exercises designed to promote critical thinking about enzyme kinetics and the role of pH with respect to optimal enzyme function. These documents can be use to incorporate a biochemistry topic into the physical chemistry curriculum or as part of an enzyme kinetics unit in a biochemistry course. Development of this document was made possible by the NSF supported 1997 "Workshop for Integration of Numerical Methods into the Undergraduate Physical Chemistry Curriculum Using the Mathcad Software" at the University of South Alabama, Mobile Alabama.
Keywords
Audiences: Upper-Division Undergraduate
Pedagogies: Computer-Based Learning, Computer-Based Learning
Domains: Physical Chemistry, Biochemistry, Laboratory Instruction
Topics: Enzymes, Kinetics, Mathematics / Symbolic Mathematics, Mechanisms of Reactions
Documents
File NameDescriptionSoftware TypeSoftware Version
EnzymeTutorial.mcd Mathcad Computational Document Mathcad
EnzymeExercise.mcd Mathcad Computational Document Mathcad
EnzymeTutorial.pdf Read-Only Document
EnzymeExercise.pdf Read-Only Document
Comments to: Paul Krause at paulk@mail.uca.edu.
©Copyright Paul Krause, 1998. All rights reserved. You are welcome to use this document in your own classes but commercial use is not allowed without the permission of the author.