11 Results
The Amino Acids   
(Other (1))
A section of ChemPrime, the Chemical Educations Digital Library's free General Chemistry textbook.
Properties of Alkanes   
(Other (1))
A section of ChemPrime, the Chemical Educations Digital Library's free General Chemistry textbook.
Polarized Light and Organic Molecules   
(Movie/Animation, Audio/Visual (6))
Polarizing filters and the rotation of polarized light by chiral compounds are demonstrated and a polarimeter is shown. Several everyday objects are examined between polarizing filters.
Polarized Light and Organic Molecules: Everyday Objects   
(Movie/Animation, Audio/Visual (6))
The liquid crystal display of a calculator and several plastic objects are examined between polarizing filters.
Chiral and Achiral Objects   
(Movie/Animation, Audio/Visual (6))
A snail shell, pencil, glove, hand, and molecular models are shown with their mirror reflections.
Chirality   
(Movie/Animation, Audio/Visual (5))
A series of chiral and achiral objects, the interaction of polarized light with organic molecules, the assignment of R- and S- configuration, Fisher projections, and a stereospecific reaction are demonstrated.
Glyceraldehyde and the Fischer Projection   
(Movie/Animation, Audio/Visual (2))
Molecular models are used to demonstrate chirality of glyceraldehyde and drawing its Fischer Projection.
Collection of Chiral Drug, Pesticide, and Fragrance Molecular Models   
(Interactive Simulation (1))
The article by Mannschreck, Kiessewetter, and von Angerer on the differential interactions between enantiomers and biological receptors (1) is the source for this month's Featured Molecules. Included in the molecule collection are all of the molecules described in the paper. In many instances we have included structures of multiple optical isomers of the same molecule so that students can not only see the forms that are active, but those that are less active, inactive, or act in an undesirable manner. These molecules will serve as good practice in determining optical configurations, and will also introduce additional forms of isomerism that students may be less familiar with than they are with R and S. Since multiple enantiomers and diastereomers are provided, students may use these molecules, together with an appropriate computational package, to verify that enantiomers have the same energy while diastereomers do not. The tuberculosis drug ethambutol provides an interesting case as both nitrogen atoms are also chiral as well as the two chiral carbon atoms. A calculation on a given structure will include the effect of that nitrogen chirality, although nitrogen inversion is expected to be quite rapid in this molecule. The conformations for the ethambutol molecules that are included here consider all four chiral atoms and are of the form (CNNC). A reasonable computational exercise would be to find the transition state for nitrogen inversion and the barrier height for that process. The supplemental material that is included with the featured article (1) includes a number of molecules that we will add to the collection as time permits. The result, including enantiomers and diastereomers, will be well over 200 additional molecules. A notice will appear in the JCE Featured Molecules column when this new set of molecules is available in JCE Online.
Stereochemistry Tutorial   
(Instructional Material (1))
Master the concepts organic stereochemistry with this interactive tutorial. It includes definitions, different three dimensional representations, assigning priorities to stereocenters, and determining the stereochemical relationship between molecules. Each section is followed by a question set that tests knowledge and understanding.
Organic : IDChiralAtoms (20 Variations)   
(Assessment Material (1))
Identify the chiral carbon atom(s), if any, in the following structure. The carbon atoms have been numbered for easier identification.


Stereochemistry (21 Variations)   
()
A collection of 21 assessment questions about Stereochemistry